Vivek Sharma
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View article: Current Status of Multi Drug Resistance- Tuberculosis: A Major Public-Health Threat
Current Status of Multi Drug Resistance- Tuberculosis: A Major Public-Health Threat Open
Background: Rifampicin is the most effective first-line antibiotic for tuberculosis (TB). However, drug resistance, particularly multidrug-resistant TB (MDR-TB), poses a significant global health challenge. According to the World Health Or…
View article: Acute poisoning with <i>Jatropha curcas</i> in North Eastern Himalayan region – A case series and review of literature
Acute poisoning with <i>Jatropha curcas</i> in North Eastern Himalayan region – A case series and review of literature Open
Plant poisoning is one of the common accidental sources of poisoning amongst the villagers and the troops going on long-range patrolling. Seeds of Jatropha curcas a/k/a biodiesel pant mimicking nuts are an uncommon source of poisoning, man…
View article: Linked PDF of Table of Contents
Linked PDF of Table of Contents Open
Stereochemical Aspects of the C-Glycosylation of Pyranosides and Furanosides
View article: Recharge the cells to overcome the debilitating symptoms in long-COVID
Recharge the cells to overcome the debilitating symptoms in long-COVID Open
Department of Respiratory Medicine, Institute of Medical Sciences and Research Centre, Kuntikana, Mangalore, Karnataka, India Address for correspondence: Dr. Sharma V, E-mail: [email protected]
View article: Self-medication: A Mechanistic Review of Common Drugs
Self-medication: A Mechanistic Review of Common Drugs Open
Migraine is a neurological disorder and a common chronic primary headache disorder characterized by acute episodes of recurrent, unilateral, pulsating, throbbing headache.The migraine attack lasts for 4-72 hours associated with or without …
View article: PIC50: An open source tool for interconversion of PIC<sub>50</sub>values and IC<sub>50</sub>for efficient data representation and analysis
PIC50: An open source tool for interconversion of PIC<sub>50</sub>values and IC<sub>50</sub>for efficient data representation and analysis Open
Half-maximal inhibitory concentration (IC 50 ) is used to determine the potency of a drug against a variety of enzymes/ biological targets associated with the pathogenesis of multiple disorders. The IC 50 values can be depicted in multiple…
View article: 2D-QSAR and Molecular Docking based virtual screening of the herbal molecules against Alzheimer’s Disorder: An approach to predict CNS activity
2D-QSAR and Molecular Docking based virtual screening of the herbal molecules against Alzheimer’s Disorder: An approach to predict CNS activity Open
Acetylcholinesterase (AChE) is one of the key enzyme targets that have been used clinically for the management of Alzheimer’s Disorder (AD). Numerous reports in the literature predict and demonstrate in-vitro , and in-silico anticholinergi…
View article: Plasmodium vivax Malaria Associated with Severe Autoimmune Hemolytic Anemia
Plasmodium vivax Malaria Associated with Severe Autoimmune Hemolytic Anemia Open
Background: Severe and/or persistent anemia due to autoimmune hemolytic anemia (AIHA) secondary to vivax malaria is a rare association. Very few cases are reported worldwide, and even less from India. AIHA occurs when immunoglobulins and/o…
View article: Endodontic management of a mandibular molar with self implanted foreign bodies and repair of furcural perforation using biodentin – A case report
Endodontic management of a mandibular molar with self implanted foreign bodies and repair of furcural perforation using biodentin – A case report Open
Foreign Bodies, whether accidently trapped or self-introduced by the patient in the tooth can not only act as a potential source of infection but may also interfere with proper cleaning and shaping and subsequent obturation of the root can…
View article: Effects of Sub-threshold Transcutaneous Auricular Vagus Nerve Stimulation on Cingulate Cortex and Insula Resting-state Functional Connectivity
Effects of Sub-threshold Transcutaneous Auricular Vagus Nerve Stimulation on Cingulate Cortex and Insula Resting-state Functional Connectivity Open
Transcutaneous auricular vagus nerve stimulation (taVNS), a non-invasive alternative to vagus nerve stimulation (VNS) with implantable devices, has shown promise in treating disorders such as depression, migraine, and insomnia. Studies of …
View article: Effect of Resonance Breathing on Heart Rate Variability and Cognitive Functions in Young Adults: A Randomised Controlled Study
Effect of Resonance Breathing on Heart Rate Variability and Cognitive Functions in Young Adults: A Randomised Controlled Study Open
View article: Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping
Cinnamomum verum-derived bioactives-functionalized gold nanoparticles for prevention of obesity through gut microbiota reshaping Open
View article: Microbial polysaccharides: An emerging family of natural biomaterials for cancer therapy and diagnostics
Microbial polysaccharides: An emerging family of natural biomaterials for cancer therapy and diagnostics Open
View article: Dysbiosis and Alzheimer’s Disease: A Role for Chronic Stress?
Dysbiosis and Alzheimer’s Disease: A Role for Chronic Stress? Open
Alzheimer’s disease (AD) is an incurable, neuropsychiatric, pathological condition that deteriorates the worth of geriatric lives. AD is characterized by aggregated senile amyloid plaques, neurofibrillary tangles, neuronal loss, gliosis, o…
View article: The Night Wanderer
The Night Wanderer Open
Lymphatic filariasis (LF) is caused by Wuchereria bancrofti (90%), Brugia malayi (<10%), and Brugia timori. Over 250 million children are exposed to LF worldwide. Common pediatric manifestations in endemic areas are asymptomatic infection …
View article: Determination of the presence of metabolic syndrome in patients of erectile dysfunction and assess correlation of its components with erectile dysfunction in a tertiary care hospital in central India
Determination of the presence of metabolic syndrome in patients of erectile dysfunction and assess correlation of its components with erectile dysfunction in a tertiary care hospital in central India Open
Background: Erectile dysfunction (ED) is a common medical condition that affects approximately 100 million men worldwide and is currently recognized as a major public health problem. Metabolic syndrome (Met S) is a complex entity consistin…
View article: ROLE OF GLUTEN FREE DIET IN CELIAC DISEASE WITH CHILDREN SUFFERING FROM SEVERE ACUTE MALNUTRITION.
ROLE OF GLUTEN FREE DIET IN CELIAC DISEASE WITH CHILDREN SUFFERING FROM SEVERE ACUTE MALNUTRITION. Open
Background: Diagnosis of celiac disease in children suffering from severe acute malnutrition without duodenal biopsy or HLA typing is a dilemma. The objective of this study was to study the response to gluten free diet in sero-positive Cel…
View article: Complications of intravesical BCG therapy in non-muscle invasive bladder cancer: our tertiary care centre experience
Complications of intravesical BCG therapy in non-muscle invasive bladder cancer: our tertiary care centre experience Open
View article: Role of microsurgical varicocelectomy in the management of non-obstructive azoospermia with varicocele: our tertiary care centre experience
Role of microsurgical varicocelectomy in the management of non-obstructive azoospermia with varicocele: our tertiary care centre experience Open
Background Varicocele is an abnormal dilation and tortuosity of the internal spermatic veins within the pampiniform plexus of the spermatic cord. Varicocele is associated with progressive testicular damage and infertility. Azoospermia is a…
View article: Tempering Macrophage Plasticity for Controlling SARS-CoV-2 Infection for Managing COVID-19 Disease
Tempering Macrophage Plasticity for Controlling SARS-CoV-2 Infection for Managing COVID-19 Disease Open
OPINION article Front. Pharmacol., 16 October 2020Sec. Inflammation Pharmacology Volume 11 - 2020 | https://doi.org/10.3389/fphar.2020.570698
View article: Role of mammary serotonin during lactational calcium homeostasis in dairy cows: Review
Role of mammary serotonin during lactational calcium homeostasis in dairy cows: Review Open
Lactation is the terminal stage of the bovine reproductive cycle and constitutes an important reproductive strategy to ensure greater survivability of newborn. One of the limitations in the production economy is postpartum disorders as inc…
View article: Aetiology, Evaluation and Management of Penile Fracture: Experience at a Teaching Hospital in Central India
Aetiology, Evaluation and Management of Penile Fracture: Experience at a Teaching Hospital in Central India Open
Introduction: Penile fracture is rupture of corpora cavernosa which occurs when the rigid penis is forcibly bent against resistance, leading to the disruption of tunica albuginea. There is classical history and physical examination before …
View article: IMPACT OF CORONAVIRUS DISEASE-19 (COVID-19) OUTBREAK ON DENTAL MEDICINE & PATIENT CARE
IMPACT OF CORONAVIRUS DISEASE-19 (COVID-19) OUTBREAK ON DENTAL MEDICINE & PATIENT CARE Open
<p>During past 3 months COVID-19 has rapidly expanded across various countries. This is a zoonotic disease which is believed to have originated in bats and pangolins and later transmitted to humans. Human transmission occurs via resp…
View article: Alzheimer’s Disorder: Epigenetic Connection and Associated Risk Factors
Alzheimer’s Disorder: Epigenetic Connection and Associated Risk Factors Open
The gene based therapeutics and drug targets have shown incredible and appreciable advances in alleviating human sufferings and complexities. Epigenetics simply means above genetics or which controls the organism beyond genetics. At presen…
View article: Long-term follow-up of traumatized immature necrotic permanent teeth treated with regenerative endodontic protocol using platelet-rich fibrin: A prospective case series
Long-term follow-up of traumatized immature necrotic permanent teeth treated with regenerative endodontic protocol using platelet-rich fibrin: A prospective case series Open
The purpose of this prospective case series was to report the long-term clinical and radiographic outcomes of regenerative endodontic procedures (REP) using platelet-rich fibrin (PRF), in traumatized immature permanent teeth with necrotic …
View article: Myositis ossificans in the diabetic foot: a review of the literature with an illustrative case series
Myositis ossificans in the diabetic foot: a review of the literature with an illustrative case series Open
Objective Myositis ossificans is a rare non-neoplastic form of heterotopic ossification most commonly described after trauma or surgery, in the diabetic foot. Design We provide a review of the literature including three illustrative cases.…
View article: Amyloid Beta Mediated Mitochondrial Dysfunction in Alzheimer's disease: A Mini Review.
Amyloid Beta Mediated Mitochondrial Dysfunction in Alzheimer's disease: A Mini Review. Open
View article: Table of contents
Table of contents Open
View article: ALZHEIMER’S DISEASE: A CONSEQUENCE OF IMPAIRED MITOPHAGY?
ALZHEIMER’S DISEASE: A CONSEQUENCE OF IMPAIRED MITOPHAGY? Open
Neurodegenerative disorders involve complexities of the pathologies, characterized by the progressive loss of neuronal viability, leading to severe physical and cognitive impairments in affected patients. These disorders although may diffe…
View article: A REVIEW ON MITOCHONDRIA AND REACTIVE OXYGEN SPECIES: THE BETTER SIDE
A REVIEW ON MITOCHONDRIA AND REACTIVE OXYGEN SPECIES: THE BETTER SIDE Open
Ever since the reactive oxygen species (ROS) were discovered in biology, the researchers have tried to understand the impact of these molecules in physiological pathways.They are known to be toxic since they are involved in plethora of dis…