Explanipedia

NCCP-ICS joint consensus-based clinical practice guidelines on medical thoracoscopy Open

Rakesh K. Chawla, Mahendra Kumar, A. Madan, Raja Dhar, Richa Gupta , et al. · 2024

Medical Thoracoscopy (MT) is commonly performed by respiratory physicians for diagnostic as well as therapeutic purposes. The aim of the study was to provide evidence-based information regarding all aspects of MT, both as a diagnostic tool…

The rising tsunami of poor muscle health and sarcopenia in Asia-Pacific: Time for focused attention and targeted interventions Open

Samuel Teong Huang Chew, Hoai Thi Thu Nguyen, Shashank Joshi, Shahrul Bahyah Kamaruzzaman, Francesco Landi , et al. · 2023

Guidelines for endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA): Joint Indian Chest Society (ICS)/Indian Association for Bronchology (IAB) recommendations Open

Anant Mohan, Karan Madan, Vijay Hadda, Saurabh Mittal, Tejas Menon Suri , et al. · 2023

Over the past decade, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become an indispensable tool in the diagnostic armamentarium of the pulmonologist. As the expertise with EBUS-TBNA has evolved and sever…

Insomnia: An Under-recognized Mental Health Catastrophe during the COVID-19 Era Open

Vivek Nangia, Amina Mobashir, Shriram Sudhakar Shenoy, Navin Dalal, Rohit R Chandran · 2023

Introduction:The coronavirus pandemic (COVID-19) has affected individuals globally in varied manners.It has also affected the psychosocial well-being, particularly of persons residing in the countries that were worst affected.In India, com…

Consensus Statement for the Diagnosis and Treatment of Idiopathic Pulmonary Fibrosis in Resource Constrained Settings Open

Randeep Guleria, Dhruva Chaudhry, Virendra Singh, Raj Kumar, Vivek Nangia , et al. · 2022

Background.Idiopathic pulmonary fibrosis (IPF) is a specific type of chronic fibrosing interstitial lung disease (ILD) that is progressive in course.Although evidence-based guidelines for IPF are available, these are difficult to interpret…

COVID-19 Risk Stratification and Mortality Prediction in Hospitalized Indian Patients: Harnessing clinical data for public health benefits Open

Shanmukh Alle, Akshay Kanakan, Samreen Siddiqui, Akshit Garg, A. Karthikeyan , et al. · 2022

The variability of clinical course and prognosis of COVID-19 highlights the necessity of patient sub-group risk stratification based on clinical data. In this study, clinical data from a cohort of Indian COVID-19 hospitalized patients is u…

Secondary infections modify the overall course of hospitalized patients with COVID-19: a retrospective study from a network of hospitals across North India Open

Sandeep Budhiraja, Bansidhar Tarai, Dinesh Kumar Jain, Mona Aggarwal, Abhaya Indrayan , et al. · 2022

Secondary infections modify the overall course of hospitalized COVID-19 patients: A retrospective study from a network of hospitals across North India Open

Sandeep Budhiraja, Bansidhar Tarai, Dinesh Kumar Jain, Mona Aggarwal, Abhaya Indrayan , et al. · 2021

Introduction SARS-CoV-2 infection increases the risk of secondary bacterial and fungal infections and contributes to adverse outcomes. The present study was undertaken to get better insights into the extent of secondary bacterial and funga…

Outcome of ventilation in patients with hypercapnic respiratory failure in IPF patients: A prospective study Open

Manjunath Hunasenahalli Krishnappa, Prasanna Kumar Thimmarayappa, Vivek Nangia, Rajat Chatterji · 2021

Background: Diffuse parenchymal lung disease (DPLD) is the inflammation and fibrosis of lung interstitium, resulting in respiratory failure. The rate of hypoxic respiratory failure is high as the disease progresses. In idiopathic pulmonary…

Profile of Mucormycosis Cases from a Network of Hospitals in North India Amidst COVID-19 Pandemic Open

Sandeep Budhiraja, Mona Aggarwal, Monica Mahajan, Abhaya Indrayan, Vinita Jha , et al. · 2021

Incidence of mucormycosis suddenly surged in India after the second wave of COVID-19. This is a crippling disease and needs to be studied in detail to understand the disease, its course, and the outcomes. Between 1 st March and 15 th July …

Differentials in the characteristics of COVID-19 cases in Wave-1 and Wave-2 admitted to a network of hospitals in North India Open

Sandeep Budhiraja, Abhaya Indrayan, Mona Aggarwal, Vinita Jha, Dinesh Kumar Jain , et al. · 2021

Second wave of COVID-19 pandemic in India came with unexpected quick speed and intensity, creating an acute shortage of beds, ventilators, and oxygen at the peak of occurrence. This may have been partly caused by emergence of new variant d…

Respiratory Co-Infections: Modulators of SARS-CoV-2 Patients’ Clinical Sub-Phenotype Open

Priyanka Mehta, Shweta Sahni, Samreen Siddiqui, Neha Mishra, Pooja Sharma , et al. · 2021

Co-infection with ancillary pathogens is a significant modulator of morbidity and mortality in infectious diseases. There have been limited reports of co-infections accompanying SARS-CoV-2 infections, albeit lacking India specific study. T…

Management of serious infections caused by metallo β-lactamases with or without OXA-48-like expressing Enterobacterales with aztreonam and ceftazidime/avibactam combination: Dosing strategy for better clinical outcome Open

Balaji Veeraraghavan, Yamuna Devi Bakthavatchalam, Rajeev Soman, S. Subramanian, A Javad Manesh , et al. · 2021

Serious infections caused by MBLs with or without OXA-48-like expressing Enterobacterales remain challenging to treat. Since aztreonam is stable to MBLs, it can be combined with ceftazidime/avibactam to protect against concurrently express…

Conventional flexible bronchoscopy during the COVID pandemic Open

Prashant N. Chhajed, Amita Nene, Nitin Abhyankar, Jayachandra Akkaraju, Ritesh Agarwal , et al. · 2021

During the times of the ongoing COVID pandemic, aerosol-generating procedures such as bronchoscopy have the potential of transmission of severe acute respiratory syndrome coronavirus 2 to the healthcare workers. The decision to perform bro…

Performance of cytology, acid-fast bacilli smear, gene Xpert and mycobacterial cultures in endobronchial ultrasound-transbronchial needle aspiration aspirate in diagnosing mediastinal tuberculous lymphadenitis Open

Venugopal Mohan, Vivek Nangia, Anoop Singh, Rahul Behl, Nitin Dumeer · 2021

Background: Diagnosis of isolated mediastinal tuberculosis (TB) can be challenging. Endobronchial ultrasound (EBUS) increases the diagnostic yield by direct sonographic visualization of mediastinal and hilar lymph nodes. With the advent of…

COVID-19 Risk Stratification and Mortality Prediction in Hospitalized Indian Patients Open

Shanmukh Alle, Samreen Siddiqui, Akshay Kanakan, Akshit Garg, A. Karthikeyan , et al. · 2020

The clinical course of coronavirus disease 2019 (COVID-19) infection is highly variable with the vast majority recovering uneventfully but a small fraction progressing to severe disease and death. Appropriate and timely supportive care can…

Consensus statement on the management of invasive candidiasis in Indian scenario Open

Prakash Shastri, Vivek Nangia, Prachee Sathe, Rajesh Pande, Abi Abraham , et al. · 2019

Invasive fungal infections in critically ill patients are associated with increased morbidity and mortality. Candida species are among the most common causes of nosocomial bloodstream infections and of invasive infections in intensive care…

1676. Incidence and Outcomes of Pulmonary Involvement in Patients with Scrub Typhus: A Clinical Study from India Open

Vivek Nangia, Amina Mobashir · 2019

Background Scrub typhus is a tropical fever caused by orrientia tsutsugamushi and is probably the most under-recognized of all the febrile illnesses leading to hospitalization, especially in India. Although the most common presenting sympt…

A Comparative Assessment of Clinical, Pharmacological and Antimicrobial Profile of Novel Anti-methicillin-resistant Staphylococcus aureus Agent Levonadifloxacin: Therapeutic Role in Nosocomial and Community Infections Open

Yamuna Devi Bakthavatchalam, Shoma V. Rao, Barney Isaac, Abi Manesh, Senthur Nambi , et al. · 2019

Staphylococcus aureus is of significant clinical concern in both community- and hospital-onset infections. The key to the success of S. aureus as a pathogen is its ability to swiftly develop antimicrobial resistance. Methicillin-resistant …

Bronchoscopic lung cryobiopsy: An Indian association for bronchology position statement Open

Ritesh Agarwal, Sahajal Dhooria, InderpaulSingh Sehgal, AshutoshNath Aggarwal, Rajiv Goyal , et al. · 2019

This position statement is an attempt to provide practical recommendations for the performance of BLC in DPLDs.

Recurrent heart failure in pulmonary tuberculosis patients on antitubercular therapy: A case of protector turning predator Open

Animesh Ray, Vivek Nangia, R Chatterji, Navin Dalal, Ruchismita Satpathy Ray · 2017

Respiratory failure in a patient with treated thymoma: A blast from the past Open

Animesh Ray, Vivek Nangia, Rajat Chatterji, Nikhil Bante · 2017

Bronchoscopy as a salvage therapy in a mechanically ventilated status asthmaticus patient: A case report Open

Animesh Ray, Vivek Nangia, Rajat Chatterji, Navin Dalal · 2017

A 23-year-old male patient presented with acute exacerbation of asthma with type 2 respiratory failure. He was mechanically ventilated and started on intensive medical therapy including nebulization with β2 agonists and antimuscarinic drug…

Convergence of Minds: For Better Patient Outcome in Intensive Care Unit Infections Open

Sarman Singh, Ashok Rattan, Neeraj Goel, Vivek Nangia, Vikas Manchanda , et al. · 2017

A close coordination between clinical microbiology and critical care medicine opens up avenues to improve antimicrobial prescription practices.

Scrub typhus infection presenting as acute heart failure: A case report and systematic review of literature of cardiopulmonary involvement in scrub typhus infection Open

Animesh Ray, Vivek Nangia, R Chatterji, Navin Dalal · 2016

We describe a middle aged previoulsy healthy female patient who presented with clinical features suggestive of acute heart failure. Investigations revealed very high NT pro-BNP, right heart enlargement, bilateral pulmonary alveolar edema a…

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