Pankaj Kumar Singh
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View article: Etiology of Anemia in Patients with Heart Failure
Etiology of Anemia in Patients with Heart Failure Open
View article: Development and standardization of iron deficient anaemic model in Wistar albino rats using laboratory prepared iron deficit diet
Development and standardization of iron deficient anaemic model in Wistar albino rats using laboratory prepared iron deficit diet Open
The current study sought to elucidate and complete the development of an iron deficiency anaemia) IDA animal model by investigating various factors such as hematology levels and histological analysis using the AIN-93G iron deficit diet.In …
View article: Adipose-derived stem cells: a pain relief treatment for intervertebral disc degeneration
Adipose-derived stem cells: a pain relief treatment for intervertebral disc degeneration Open
Intervertebral Disk Degeneration, or IVDD, refers to the natural process in which an intervertebral disk deteriorates (i.e., degenerates) over time-years and decades of life. It could result from the natural aging process or due to simple …
View article: C-45 | Effectiveness of Posterior Pericardiotomy in Reducing Postoperative Atrial Fibrillation (POAF) Following Coronary Artery Bypass Grafting (CABG): A Systematic Review & Meta-Analysis of RCTs
C-45 | Effectiveness of Posterior Pericardiotomy in Reducing Postoperative Atrial Fibrillation (POAF) Following Coronary Artery Bypass Grafting (CABG): A Systematic Review & Meta-Analysis of RCTs Open
View article: Traumatic Cervical Spondyloptosis: A Comprehensive Analysis of 16 Cases at a Level 1 Trauma Center in a Developing Nation
Traumatic Cervical Spondyloptosis: A Comprehensive Analysis of 16 Cases at a Level 1 Trauma Center in a Developing Nation Open
Background: Traumatic cervical spondyloptosis (TCS) is a rare and the most severe form of cervical spine injury. Aims/Objective: The primary and secondary objectives were assessment of improvement in neurological status and rate of complic…
View article: Prevalence of Tobacco and Alcohol Consumption and its Association with Incident Hypertension among Young Adults Residing in an Urban Area of West Bengal
Prevalence of Tobacco and Alcohol Consumption and its Association with Incident Hypertension among Young Adults Residing in an Urban Area of West Bengal Open
Background: This study was conducted to estimate the prevalence of tobacco and alcohol use among young adults and also to evaluate their association with incident hypertension in an urban area of West Bengal, India. Materials and Methods: …
View article: 38P Targeting autophagy in tumor-associated macrophages effects the phenotype and tumor progression in urothelial carcinoma of bladder
38P Targeting autophagy in tumor-associated macrophages effects the phenotype and tumor progression in urothelial carcinoma of bladder Open
Bladder cancer is common genitourinary cancer wherein Urothelial Carcinoma of Bladder (UBC) presents the major histological subtype associated with high mortality and recurrence. Tumor-associated macrophages (TAMs) constitute a large propo…
View article: A Study of the Anatomy of the Eustachian Tube for Its Surgical Approach in Otorhinolaryngology
A Study of the Anatomy of the Eustachian Tube for Its Surgical Approach in Otorhinolaryngology Open
The present study will help to locate the position of the pharyngeal opening of the ET during otorhinolaryngological evaluation for performing various surgeries in the middle ear.
View article: Primary amebic pulmonary abscess with concurrent pulmonary adenocarcinoma
Primary amebic pulmonary abscess with concurrent pulmonary adenocarcinoma Open
Amebic lung abscess without involving another system like liver or colon is immensely uncommon. We want to report a case of a 72-year-old woman who presented in emergency with complaints of shortness of breath, loss of weight, right-side c…
View article: Data from YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer
Data from YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer Open
Purpose:Esophageal cancer is a lethal disease that is often resistant to therapy. Alterations of YAP1 and CDK6 are frequent in esophageal cancer. Deregulation of both molecules may be responsible for therapy resistance.Experimental Design:…
View article: Data from YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer
Data from YAP1-Mediated CDK6 Activation Confers Radiation Resistance in Esophageal Cancer – Rationale for the Combination of YAP1 and CDK4/6 Inhibitors in Esophageal Cancer Open
Purpose:Esophageal cancer is a lethal disease that is often resistant to therapy. Alterations of YAP1 and CDK6 are frequent in esophageal cancer. Deregulation of both molecules may be responsible for therapy resistance.Experimental Design:…
View article: Technique of Distraction, Compression, Extension, Reduction to Reduce and Realign Old Displaced Odontoid Fracture From Posterior Approach: A Novel Technique
Technique of Distraction, Compression, Extension, Reduction to Reduce and Realign Old Displaced Odontoid Fracture From Posterior Approach: A Novel Technique Open
Objective: Chronic ‘displaced’ displaced type II fractures, though uncommon, are difficult to manage. They usually require a transoral procedure followed by a posterior instrumented fusion. We describe here, a new method to reduce the frac…
View article: Robotic Total Knee Arthroplasty in Post-Traumatic Osteoarthritis: A Report of Three Cases
Robotic Total Knee Arthroplasty in Post-Traumatic Osteoarthritis: A Report of Three Cases Open
Background:The purpose of this case study is to present three cases in which the robotic assisted TKA device was used to correct a severe post traumatic osteoarthritis.Routine conventional TKA in complex PTOA can be challenging and difficu…
View article: Managing Traumatic Brain Injury During the Coronavirus Disease 2019 Pandemic–A Case-Matched Controlled Analysis of Immediate Outcomes
Managing Traumatic Brain Injury During the Coronavirus Disease 2019 Pandemic–A Case-Matched Controlled Analysis of Immediate Outcomes Open
View article: Anthropometric assessment of human auricle in North Indian population
Anthropometric assessment of human auricle in North Indian population Open
Introduction: Morphometric studies of the auricle find its place in many areas, such as esthetics, forensic medicine, biology, anthropology, mythology, arts, and acupuncture. Aims and Objective: This study aims at establishing the anatomic…
View article: Timely diagnosis and intervention in a case of portal vein thrombosis: A life saved!
Timely diagnosis and intervention in a case of portal vein thrombosis: A life saved! Open
Dear Editor, A 51-year female patient with ca sigmoid colon and liver metastasis who underwent synchronous sigmoid colectomy with right hepatectomy. Preoperative CT scan revealed aberrant arterial anatomy (right anterior and posterior sect…
View article: Micro (mi) RNA and Diabetic Retinopathy
Micro (mi) RNA and Diabetic Retinopathy Open
View article: CASC5 is a potential cancer-testis gene in human urinary bladder transitional cell carcinoma
CASC5 is a potential cancer-testis gene in human urinary bladder transitional cell carcinoma Open
Urinary Bladder cancer (UBC) is a diversified disease with an array of clinicopathological attributes. Several studies have shown that cancer susceptibility candidate 5 (CASC5) plays important roles in various types of malignancies; howeve…
View article: Sagittal and Coronal Plane Fracture of Talar Body, An Unusual Combination with Medial Malleolus Fracture: A Case Report
Sagittal and Coronal Plane Fracture of Talar Body, An Unusual Combination with Medial Malleolus Fracture: A Case Report Open
Introduction: Fractures of the talus are relatively uncommon injuries with majority of them involving the neck region. Talar body fracture in sagittal plane in combination with medial malleolus fracture is very rare with few cases being re…
View article: Patient Characteristics and Clinical and Intraoperative Variables Affecting Outcome in Pediatric Traumatic Brain Injury
Patient Characteristics and Clinical and Intraoperative Variables Affecting Outcome in Pediatric Traumatic Brain Injury Open
Background Pediatric traumatic brain injury (TBI) has distinctive pathophysiology and characteristics that differ from adults. These can be attributed to age-related anatomical and physiological differences and distinct patterns of injurie…
View article: Frequent expression of a novel cancer testis antigen, protein kinase human monopolar spindle 1 (hMps1/TTK) in human urinary bladder transitional cell carcinoma
Frequent expression of a novel cancer testis antigen, protein kinase human monopolar spindle 1 (hMps1/TTK) in human urinary bladder transitional cell carcinoma Open
Urothelial bladder cancer (UBC) is a frequently occurring malignancy of the urinary tract. The present study was undertaken to evaluate the mRNA and immunohistochemical (IHC) expression of protein kinase human monopolar spindle 1 (hMps1/TT…
View article: Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population
Leptin DNA Methylation and Its Association with Metabolic Risk Factors in a Northwest Indian Obese Population Open
The leptin epigenetic profile may be associated with obesity and its associated metabolic risk factors.
View article: Respiratory morbidity and mortality of traumatic cervical spinal cord injury at a level I trauma center in India
Respiratory morbidity and mortality of traumatic cervical spinal cord injury at a level I trauma center in India Open
View article: Surgery for Vertebral Hemangioma in Resource-Constrained Environment
Surgery for Vertebral Hemangioma in Resource-Constrained Environment Open
View article: Spontaneous external rupture of hydrocephalus after fontanelle closure: a case report and review of literature
Spontaneous external rupture of hydrocephalus after fontanelle closure: a case report and review of literature Open
View article: Esophageal Fistula following Anterior Cervical Discectomy and Fusion in Traumatic Cervical Injury Cases: A Review
Esophageal Fistula following Anterior Cervical Discectomy and Fusion in Traumatic Cervical Injury Cases: A Review Open
Background Esophageal fistula is a very rare complication associated with anterior approaches to the cervical spine. Timely diagnosis and early intervention are associated with favorable outcomes. There is a dilemma in the literature for i…
View article: Management of neglected complex hangman’s fracture by reforming the C2 pedicle: new innovative technique of motion preservation at the C1–2 joint in 2 cases
Management of neglected complex hangman’s fracture by reforming the C2 pedicle: new innovative technique of motion preservation at the C1–2 joint in 2 cases Open
Hangman’s fracture, also known as traumatic spondylolisthesis of the axis, causes widening of the neural canal and thus a low rate of neurological deficits. This low rate is one of the reasons it is neglected and patients present with late…
View article: Diametral Growth and Hardness Variation in Al6101 T6 during Flow Forming
Diametral Growth and Hardness Variation in Al6101 T6 during Flow Forming Open
Flow forming is an emerging process being widely used for manufacturing axisymmetric components that are used in the aerospace industry and automobile industries. In the present investigation, the mechanical response of the Al6101 T6 workp…
View article: Letter to Editor. Giant intracranial aneurysms of the posterior circulation
Letter to Editor. Giant intracranial aneurysms of the posterior circulation Open
regarding the potential role of annexin A7 (ANXA7) in the pathological process of subarachnoid hemorrhage (SAH) in a rat model.In this article, the data demonstrated that ANXA7 was upregulated after SAH and caused the overproduction of glu…
View article: Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants
Basilar Invagination and Atlantoaxial Dislocation: Reduction, Deformity Correction and Realignment Using the DCER (Distraction, Compression, Extension, and Reduction) Technique With Customized Instrumentation and Implants Open
Occipito-C2 pseudo-joints are important in determining the severity of BI. Asymmetrical pseudo-joint causes coronal/neck tilt. Type of pseudo-joint can strategize by DCER. Customized instruments and implants make technique safe, effective …