Vladimir Bogin
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View article: We Need to Talk About Quality of Life with Cancer Patients: Primum Non Nocere in Oncology
We Need to Talk About Quality of Life with Cancer Patients: Primum Non Nocere in Oncology Open
The Hippocratic principle primum non nocere, or “first, do no harm”, serves as a vital lens through which to re-evaluate modern oncology practices. While recent advances such as immunotherapy, targeted agents, and precision medicine have t…
View article: Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment Elevation Myocardial Infarction: Secondary End Points From an International, Double-Blind, Randomized, Placebo-Controlled, Phase 2a Study
Interleukin-1 Blockade With RPH-104 (Goflikicept) in Patients With ST-Segment Elevation Myocardial Infarction: Secondary End Points From an International, Double-Blind, Randomized, Placebo-Controlled, Phase 2a Study Open
In a randomized double-blinded clinical trial of patients with ST segment elevation myocardial infarction (STEMI), goflikicept, an interleukin-1 blocker, significantly reduced systemic inflammation, measured as the area under the curve (AU…
View article: Effects of inhaled low-concentration xenon gas on naltrexone-precipitated withdrawal symptoms in morphine-dependent mice
Effects of inhaled low-concentration xenon gas on naltrexone-precipitated withdrawal symptoms in morphine-dependent mice Open
View article: Lasagna's law: A dish best served early
Lasagna's law: A dish best served early Open
It has been over 40 years since Lasagna's Law was first introduced and its main postulates are still permeating the clinical trial arena. This article attempts to identify the most pressing roadblocks in patient recruitment, categorizes th…
View article: Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale
Interleukin-1 blockade with RPH-104 in patients with acute ST-elevation myocardial infarction: study design and rationale Open
View article: Interleukin-1 Blockade With RPH-104 in Patients With Acute ST-Elevation Myocardial Infarction: Study Design and Rationale.
Interleukin-1 Blockade With RPH-104 in Patients With Acute ST-Elevation Myocardial Infarction: Study Design and Rationale. Open
Background Myocardial injury of ST-segment elevation myocardial infarction (STEMI) initiates an intense inflammatory response that contributes to further damage and is a predictor of increased risk of death or heart failure (HF). Interleuk…
View article: Clinical characteristics of dermatologic manifestations of COVID‐19 infection: case series of 15 patients, review of literature, and proposed etiological classification
Clinical characteristics of dermatologic manifestations of COVID‐19 infection: case series of 15 patients, review of literature, and proposed etiological classification Open
Presently, the exact dermatologic manifestations of COVID-19 infection, its characteristics, prevalence, temporal relationship to other clinical findings, and severity of underlying illness are still being evaluated. The first report on su…
View article: Master protocols: New directions in drug discovery
Master protocols: New directions in drug discovery Open
View article: Beneficial effects of xenon inhalation on behavioral changes in a valproic acid-induced model of autism in rats
Beneficial effects of xenon inhalation on behavioral changes in a valproic acid-induced model of autism in rats Open
View article: Argon Mitigates Impaired Wound Healing Process and Enhances Wound Healing <i>In Vitro</i> and <i>In Vivo</i>
Argon Mitigates Impaired Wound Healing Process and Enhances Wound Healing <i>In Vitro</i> and <i>In Vivo</i> Open
Diabetic foot ulcers are associated with significant morbidity and mortality, and current treatments are far from optimal. Chronic wounds in diabetes are characterised by impaired angiogenesis, leukocyte function, fibroblast proliferation,…
View article: Xenon in the treatment of panic disorder: an open label study
Xenon in the treatment of panic disorder: an open label study Open
View article: Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine
Induction and characterization of anti-tumor endothelium immunity elicited by ValloVax therapeutic cancer vaccine Open
ValloVax is a placental endothelium derived vaccine which induces tissue-nonspecific antitumor immunity by blocking tumor angiogesis. To elucidate mechanisms of action, we showed that production of ValloVax, which involves treating placent…
View article: DRUGS PROVIDED TO BREAST CANCER PATIENTS WITHIN THE STATE PROGRAMS OF DRUG SUPPLY
DRUGS PROVIDED TO BREAST CANCER PATIENTS WITHIN THE STATE PROGRAMS OF DRUG SUPPLY Open
The purpose of our research was to analyze the actual practice of medicine in patients with breast cancer in various regions of the Russian Federation in the framework of state programs of drug provision (procurement of essential drugs (ED…
View article: Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?
Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique? Open
Angiogenesis is essential for the growth and metastasis of solid tumors. The tumor endothelium exists in a state of chronic activation and proliferation, fueled by the tumor milieu where angiogenic mediators are aberrantly over-expressed. …