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View article: Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus
Breaking the cycle: considerations for a life-course vaccination strategy against varicella-zoster virus Open
Varicella and HZ pose significant burdens. The availability of effective vaccines with established safety profiles means that prevention of both manifestations of VZV disease is now largely possible. Reasons why National Immunization Techn…
View article: Toward elimination of hepatitis A and B in Europe: vaccination successes, challenges, and opportunities
Toward elimination of hepatitis A and B in Europe: vaccination successes, challenges, and opportunities Open
Awareness of at-risk populations and HBV/HAV vaccination recommendations should be raised among healthcare providers and the general population to increase access to vaccination. Increasing awareness that HBV vaccination contributes to red…
View article: Response letter Re: The burden of seasonal influenza: improving vaccination coverage to mitigate morbidity and its impact on healthcare systems
Response letter Re: The burden of seasonal influenza: improving vaccination coverage to mitigate morbidity and its impact on healthcare systems Open
KEYWORDS: COVID-19 pandemicinfectious diseasesvaccinepreventable diseasesrhinovirusresurgencerespiratory syncytial virusnorovirusoutbreaksnonpharmaceutical interventionsinfluenza
View article: 571. A Report of the Postmarketing Spontaneous Safety Data over 24 Years for GSK’s Measles-Mumps-Rubella (MMR) Vaccine
571. A Report of the Postmarketing Spontaneous Safety Data over 24 Years for GSK’s Measles-Mumps-Rubella (MMR) Vaccine Open
Background GSK’s measles-mumps-rubella (MMR) vaccine is indicated for active immunization of individuals aged 12 months and older against these 3 serious illnesses. It is licensed in > 100 countries worldwide not including the US. In cl…
View article: Lifting non-pharmaceutical interventions following the COVID-19 pandemic – the quiet before the storm?
Lifting non-pharmaceutical interventions following the COVID-19 pandemic – the quiet before the storm? Open
Awareness must be raised of the risk of vaccine-preventable disease resurgence, and efforts need to be made to mitigate this risk, where possible, by increasing vaccination coverage. Research and regulatory opportunities brought on by the …
View article: Recommendations for the ethical conduct of vaccination awareness campaigns by biopharmaceutical companies
Recommendations for the ethical conduct of vaccination awareness campaigns by biopharmaceutical companies Open
Health awareness campaigns educate and inform the public about particular health conditions with the aim of either changing behavior or enhancing uptake of appropriate healthcare, such as vaccination or screening. The campaigns may be run …
View article: Systematic review of the efficacy, effectiveness and impact of high-valency pneumococcal conjugate vaccines on otitis media
Systematic review of the efficacy, effectiveness and impact of high-valency pneumococcal conjugate vaccines on otitis media Open
Otitis media (OM) is a common disease of childhood and available pneumococcal conjugate vaccines (PCVs), with different compositions, could have different impact on OM reduction. This systematic literature review evaluated available data d…
View article: Measles, mumps, rubella prevention: how can we do better?
Measles, mumps, rubella prevention: how can we do better? Open
While vaccines against measles, mumps, and rubella (including trivalent vaccines) are widely used and effective, challenges to control these diseases are mainly related to insufficient immunization coverage and changing vaccination needs o…
View article: Established and new rotavirus vaccines: a comprehensive review for healthcare professionals
Established and new rotavirus vaccines: a comprehensive review for healthcare professionals Open
Robust scientific evidence related to two rotavirus (RV) vaccines available worldwide demonstrates their significant impact on RV disease burden. Improving RV vaccination coverage may result in better RV disease control. To make RV vaccina…
View article: Underlying factors in paediatric invasive pneumococcal disease in Belgium
Underlying factors in paediatric invasive pneumococcal disease in Belgium Open
View article: Fifteen years of experience with the oral live-attenuated human rotavirus vaccine: reflections on lessons learned
Fifteen years of experience with the oral live-attenuated human rotavirus vaccine: reflections on lessons learned Open
In clinical trials, HRV displayed an acceptable safety profile and efficacy against RV-gastroenteritis, providing broad protection against heterotypic RV strains by reducing the consequences of severe RV disease in infants. Real-world evid…
View article: Association between rotavirus gastroenteritis and intussusception: suggested evidence from a retrospective study in claims databases in the United States
Association between rotavirus gastroenteritis and intussusception: suggested evidence from a retrospective study in claims databases in the United States Open
The etiology of intussusception (IS), a serious gastrointestinal obstruction, remains unclear. Limited evidence suggests a role for viral infection. We investigated the risk of IS after rotavirus gastroenteritis (RV GE) in the first year o…
View article: Rotavirus vaccination and intussusception: a paradigm shift?
Rotavirus vaccination and intussusception: a paradigm shift? Open
Rotavirus (RV) is one of the leading causes of severe childhood gastroenteritis in children <5 years of age. Several countries have successfully implemented vaccination against RV disease; however, hesitancy to include RV vaccination in th…
View article: Association between rotavirus gastroenteritis and intussusception: suggested evidence from a retrospective study in claims databases in the United States. Corresponding author: Corinne Willame, MPH, GSK, 20 Avenue Fleming, Wavre, Belgium
Association between rotavirus gastroenteritis and intussusception: suggested evidence from a retrospective study in claims databases in the United States. Corresponding author: Corinne Willame, MPH, GSK, 20 Avenue Fleming, Wavre, Belgium Open
Background: The etiology of intussusception (IS), a serious medical condition of acute gastrointestinal obstruction, remains unclear. Limited evidence suggests a role for viral infections, including rotavirus infection. This study aimed to…
View article: Role of healthcare practitioners in rotavirus disease awareness and vaccination – insights from a survey among caregivers
Role of healthcare practitioners in rotavirus disease awareness and vaccination – insights from a survey among caregivers Open
An online survey was designed to assess awareness and understanding of Rotavirus (RV) gastroenteritis (RVGE), and knowledge and attitudes towards RV vaccination in Germany, Poland, Turkey, Indonesia, the Philippines and Thailand. Survey pa…
View article: Reply to Lee et al.’s letter to the editor pertaining to our publication entitled “Pain caused by measles, mumps, and rubella vaccines: A systematic literature review”
Reply to Lee et al.’s letter to the editor pertaining to our publication entitled “Pain caused by measles, mumps, and rubella vaccines: A systematic literature review” Open
View article: Impact of history of febrile convulsions on the risk difference of febrile convulsions with the tetravalent measles–mumps–rubella–varicella vaccine: Post-hoc exploratory analysis of results from a matched-cohort study
Impact of history of febrile convulsions on the risk difference of febrile convulsions with the tetravalent measles–mumps–rubella–varicella vaccine: Post-hoc exploratory analysis of results from a matched-cohort study Open
This post-hoc analysis of data from a matched cohort study investigated the risk of febrile convulsions (FC) 5-12 days post-first dose of measles-mumps-rubella-varicella vaccine (MMRV) in a low-risk population, compared to measles-mumps-ru…
View article: Understanding modern-day vaccines: what you need to know
Understanding modern-day vaccines: what you need to know Open
Vaccines are considered to be one of the greatest public health achievements of the last century. Depending on the biology of the infection, the disease to be prevented, and the targeted population, a vaccine may require the induction of d…
View article: Pain caused by measles, mumps, and rubella vaccines: A systematic literature review
Pain caused by measles, mumps, and rubella vaccines: A systematic literature review Open
To our knowledge, this review summarizes for the first time the available scientific evidence on the intensity of pain following different MMR vaccines. It highlights that MMR vaccines can differ in terms of immediate pain. Further researc…
View article: Parents' insights after pediatric hospitalization due to rotavirus gastroenteritis in Italy
Parents' insights after pediatric hospitalization due to rotavirus gastroenteritis in Italy Open
Most of the severe cases of acute gastroenteritis in infants and children under 5 globally are caused by rotavirus infection. There are nearly 15,000 rotavirus gastroenteritis (RVGE) hospitalizations in Italy each year, which could be redu…
View article: Erratum to: ‘Identification and characterization of the bacterial etiology of clinically problematic acute otitis media after tympanocentesis or spontaneous otorrhea in German children’
Erratum to: ‘Identification and characterization of the bacterial etiology of clinically problematic acute otitis media after tympanocentesis or spontaneous otorrhea in German children’ Open
View article: Routinely vaccinating adolescents against meningococcus: targeting transmission & disease
Routinely vaccinating adolescents against meningococcus: targeting transmission & disease Open
Adolescents have the highest rates of meningococcal carriage and transmission. Interrupting the adolescent habitat in order to reduce carriage and transmission within adolescents and to other age groups could help to control meningococcal …