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Desulfovibrio bacteria enhance alpha-synuclein aggregation in a Caenorhabditis elegans model of Parkinson’s disease Open

Vy A. Huynh, Timo M. Takala, Kari Murros, Bidhi Diwedi, Per E. J. Saris · 2023

Introduction The aggregation of the neuronal protein alpha-synuclein (alpha-syn) is a key feature in the pathology of Parkinson’s disease (PD). Alpha-syn aggregation has been suggested to be induced in the gut cells by pathogenic gut micro…

Desulfovibrio Bacteria Are Associated With Parkinson’s Disease Open

Kari Murros, Vy A. Huynh, Timo M. Takala, Per E. J. Saris · 2021

Parkinson’s disease (PD) is the most prevalent movement disorder known and predominantly affects the elderly. It is a progressive neurodegenerative disease wherein α-synuclein, a neuronal protein, aggregates to form toxic structures in ner…