W. J. Burke
YOU?
Author Swipe
View article: Ecological and evolutionary dynamics to design and improve ovarian cancer treatment
Ecological and evolutionary dynamics to design and improve ovarian cancer treatment Open
Ovarian cancer ecosystems are exceedingly complex, consisting of a high heterogeneity of cancer cells. Development of drugs such as poly ADP‐ribose polymerase (PARP) inhibitors, targeted therapies and immunotherapies offer more options for…
View article: Blood‐based biomarkers for predicting treatment response in the Apathy in Dementia Methylphenidate Trial 2 randomized clinical trial
Blood‐based biomarkers for predicting treatment response in the Apathy in Dementia Methylphenidate Trial 2 randomized clinical trial Open
Background The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2) found that methylphenidate (MPH) was modestly efficacious is treating apathy in Alzheimer’s disease (AD) with 66% response (> = 4 point decrease on Neuropsychiatric Invent…
View article: Executive Summary of the Lower Anogenital Tract Cancer Evidence Review Conference
Executive Summary of the Lower Anogenital Tract Cancer Evidence Review Conference Open
The Centers for Disease Control and Prevention sponsored a project conducted by the American College of Obstetricians and Gynecologists to develop educational materials for clinicians on the prevention and early diagnosis of gynecologic ca…
View article: Health Disparities in Ovarian Cancer
Health Disparities in Ovarian Cancer Open
Health disparity , defined by the Centers for Disease Control and Prevention (CDC) as “preventable differences in the burden of disease, injury, violence, or opportunities to achieve optimal health that are experienced by socially disadvan…
View article: EP417/#795 Value of surgical lymph node assessment for patients with vulvar melanoma
EP417/#795 Value of surgical lymph node assessment for patients with vulvar melanoma Open
Objectives Investigate the utilization and outcomes of lymphadenectomy (LND) for patients with vulvar melanoma. Methods Patients with vulvar melanoma, known depth of tumor invasion, no distant metastases, with/without inguinal lymph node s…
View article: EP141/#791 Does positive peritoneal cytology alter oncologic outcomes of patients with clinical early stage low-grade endometrioid endometrial carcinoma?
EP141/#791 Does positive peritoneal cytology alter oncologic outcomes of patients with clinical early stage low-grade endometrioid endometrial carcinoma? Open
Objectives Investigate the prevalence and outcomes of positive peritoneal cytology among patients with clinical early stage low-grade endometrioid endometrial carcinoma (EEC). Methods Patients with no history of another tumor diagnosed bet…
View article: Design and Development of a Community-Based, Interdisciplinary, Collaborative Dementia Care Program
Design and Development of a Community-Based, Interdisciplinary, Collaborative Dementia Care Program Open
A pilot Dementia Care Partners demonstrated feasibility and suggested acceptability, and high satisfaction among primary care providers and caregivers.
View article: Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease
Effect of Methylphenidate on Apathy in Patients With Alzheimer Disease Open
ClinicalTrials.gov Identifier: NCT02346201.
View article: Health Outcomes Associated with Adherence to Antidepressant Use during Acute and Continuation Phases of Depression Treatment among Older Adults with Dementia and Major Depressive Disorder
Health Outcomes Associated with Adherence to Antidepressant Use during Acute and Continuation Phases of Depression Treatment among Older Adults with Dementia and Major Depressive Disorder Open
Objectives: To examine health outcomes associated with adherence to Healthcare Effectiveness Data and Information Set (HEDIS) antidepressant medication management (AMM) during acute and continuation phases of depression treatment among old…
View article: <p>Extent and Factors Associated with Adherence to Antidepressant Treatment During Acute and Continuation Phase Depression Treatment Among Older Adults with Dementia and Major Depressive Disorder</p>
Extent and Factors Associated with Adherence to Antidepressant Treatment During Acute and Continuation Phase Depression Treatment Among Older Adults with Dementia and Major Depressive Disorder Open
Approximately, 74% and 64% older adults with dementia and MDD were adherent to acute and continuation phase antidepressant treatment in this nationally representative sample of Medicare beneficiaries, and we identified several modifiable a…
View article: Auroral hydrogen emissions: a historic survey
Auroral hydrogen emissions: a historic survey Open
Auroral spectroscopy provided the first tool for remotely sensing the compositions and dynamics of the high-latitude ionosphere. In 1885, Balmer discovered that the visible hydrogen spectrum consists of a series of discrete lines whose wav…
View article: Alzheimer's disease medication and risk of all‐cause mortality and all‐cause hospitalization: A retrospective cohort study
Alzheimer's disease medication and risk of all‐cause mortality and all‐cause hospitalization: A retrospective cohort study Open
Introduction Identifying Alzheimer's disease (AD) pharmacologic treatment options that effectively reduce the risk of mortality and hospitalization in real‐world settings is critical. Methods We compared donepezil, galantamine, memantine, …
View article: Machine learning models to predict onset of dementia: A label learning approach
Machine learning models to predict onset of dementia: A label learning approach Open
Introduction The study objective was to build a machine learning model to predict incident mild cognitive impairment, Alzheimer's Disease, and related dementias from structured data using administrative and electronic health record sources…
View article: Thermospheric Dynamics during the March 1989 Magnetic Storm
Thermospheric Dynamics during the March 1989 Magnetic Storm Open
During the magnetic superstorm of 13-14 March 1989, approximately 2500 space objects in low Earth orbits (LEO) were "lost" by the U.S. Space Surveillance Network.Modeling disturbance effects on satellite drag intensified throughout the fol…
View article: Identification of Baseline Characteristics Associated With Development of Depression Among Patients With Head and Neck Cancer
Identification of Baseline Characteristics Associated With Development of Depression Among Patients With Head and Neck Cancer Open
Baseline symptoms and initial radiotherapy-based treatment may be associated with development of moderate or greater depression in patients with HNC. Patients with QIDS-SR baseline scores of 2 or higher may benefit the most from pharmacolo…
View article: P3‐027: RECRUITMENT STRATEGIES FOR ALZHEIMER'S PREVENTION TRIALS
P3‐027: RECRUITMENT STRATEGIES FOR ALZHEIMER'S PREVENTION TRIALS Open
Recruitment remains a significant obstacle to the successful execution of most AD clinical trials, even more so in an era where persons with preclinical AD are sought who possess very specific profiles based on risk factors such as age, ge…
View article: Timing of mass spawning in corals: potential influence of the coincidence of lunar factors and associated changes in atmospheric pressure from northern and southern hemisphere case studies
Timing of mass spawning in corals: potential influence of the coincidence of lunar factors and associated changes in atmospheric pressure from northern and southern hemisphere case studies Open
Synchronised multispecies mass spawning events are striking features of reproduction in corals. This synchronous gamete release of thousands of animals over vast stretches of reef is thought to be cued by rhythms of the Moon. However, the …
View article: Timing of mass spawning in corals: potential influence of the coincidence of lunar factors and associated changes in atmospheric pressure from northern and southern hemisphere case studies
Timing of mass spawning in corals: potential influence of the coincidence of lunar factors and associated changes in atmospheric pressure from northern and southern hemisphere case studies Open
Synchronised multispecies mass spawning events are striking features of reproduction in corals. This synchronous gamete release of thousands of animals over vast stretches of reef is thought to be cued by rhythms of the Moon. However, the …
View article: Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer’s Disease: A Double-Blind, Randomized, Placebo-Controlled Trial
Methylphenidate for Apathy in Community-Dwelling Older Veterans With Mild Alzheimer’s Disease: A Double-Blind, Randomized, Placebo-Controlled Trial Open
Methylphenidate improved apathy in a group of community-dwelling veterans with mild Alzheimer's disease. Methylphenidate also improved cognition, functional status, caregiver burden, CGI scores, and depression.
View article: [O1–01–06]: MEASURING APATHY IN ALZHEIMER'S DISEASE IN THE APATHY IN DEMENTIA METHYLPHENIDATE TRIAL 2 (ADMET 2): A COMPARISON OF INSTRUMENTS
[O1–01–06]: MEASURING APATHY IN ALZHEIMER'S DISEASE IN THE APATHY IN DEMENTIA METHYLPHENIDATE TRIAL 2 (ADMET 2): A COMPARISON OF INSTRUMENTS Open
Apathy is the most commonly observed neuropsychiatric syndrome (NPS) in Alzheimer's disease (AD), occurring in approximately 49% of individuals with AD. However, diagnosis of apathy is particularly difficult, as its symptoms can overlap wi…
View article: Storm time coupling between the magnetosheath and the polar ionosphere
Storm time coupling between the magnetosheath and the polar ionosphere Open
The present study demonstrates the feasibility of using plasma and magnetic field data from Defense Meteorological Satellite Program (DMSP) satellites to estimate the Alfvénic reflectances ( α ) in the polar cap ionosphere during periods o…
View article: C/NOFS remote sensing of ionospheric reflectance
C/NOFS remote sensing of ionospheric reflectance Open
Alfvén waves play critical roles in the electrodynamic coupling of plasmas at magnetically conjugate regions in near‐Earth space. Associated electric ( E* ) and magnetic ( δB* ) field perturbations sampled by sensors on satellites in low‐E…
View article: O<sup>+</sup> ion conic and plasma sheet dynamics observed by Van Allen Probe satellites during the 1 June 2013 magnetic storm
O<sup>+</sup> ion conic and plasma sheet dynamics observed by Van Allen Probe satellites during the 1 June 2013 magnetic storm Open
The Van Allen Probe satellites were near apogee in the late evening local time sector during the 1 June 2013 magnetic storm's main phase. About an hour after crossing the ring current's “nose structure” into the plasma sheet, the satellite…