Richard Morris
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View article: Impact of Nebulized BromAc® on Mucus Plug Clearance in a Mechanically Ventilated Ex Vivo Ovine Lung Model of Obstructive Respiratory Conditions
Impact of Nebulized BromAc® on Mucus Plug Clearance in a Mechanically Ventilated Ex Vivo Ovine Lung Model of Obstructive Respiratory Conditions Open
Mucus plugging of the respiratory tract occurs in airway diseases, including asthma, chronic obstructive pulmonary disease, and cystic fibrosis. It can cause blockage of the airways, leading to breathlessness and lung failure. Here, we use…
View article: External validation of a prognostic model to improve prediction of psychosis: a retrospective cohort study in primary care
External validation of a prognostic model to improve prediction of psychosis: a retrospective cohort study in primary care Open
Background Early detection could reduce the duration of untreated psychosis. GPs are a vital part of the psychosis care pathway, but find it difficult to detect the early features. An accurate risk prediction tool, P Risk, was developed to…
View article: Effect of Nebulised BromAc<sup>®</sup> on Mucus Plug in a Mechanically Ventilated Ex-Vivo Ovine Lung Model for Obstructive Respiratory Tract
Effect of Nebulised BromAc<sup>®</sup> on Mucus Plug in a Mechanically Ventilated Ex-Vivo Ovine Lung Model for Obstructive Respiratory Tract Open
Mucus plugging of the respiratory tract occurs in airway diseases, including asthma, chronic obstructive pulmonary disease and cystic fibrosis. It can cause blockage of airways, leading to breathlessness and lung failure. Here, we demonstr…
View article: Adrenal cortical adenoma arising in the setting of renal–adrenal fusion: a case report and review of the literature
Adrenal cortical adenoma arising in the setting of renal–adrenal fusion: a case report and review of the literature Open
Background Renal–adrenal fusion is a rare entity resulting from incomplete encapsulation of the adrenal gland and kidney. Only 18 cases have been reported in English literature to date. Case presentation Our patient is a 77-year-old Africa…
View article: Antidepressants in pregnancy: applying causal epidemiological methods to understand service-use outcomes in women and long-term neurodevelopmental outcomes in exposed children
Antidepressants in pregnancy: applying causal epidemiological methods to understand service-use outcomes in women and long-term neurodevelopmental outcomes in exposed children Open
Background Antidepressants are commonly prescribed during pregnancy, despite a lack of evidence from randomised trials on the benefits or risks. Some studies have reported associations of antidepressants during pregnancy with adverse offsp…
View article: Listening to the patient voice on home-based cardiac rehabilitation: a qualitative audit mapping patient-reported outcomes to current european guidelines
Listening to the patient voice on home-based cardiac rehabilitation: a qualitative audit mapping patient-reported outcomes to current european guidelines Open
Funding Acknowledgements Type of funding sources: Public Institution(s). Main funding source(s): NHS Lothian. Background and Purpose Increasing evidence supports the efficacy of facilitated home-based cardiac rehabilitation as an alternati…
View article: Effectiveness of Project ECHO Programs in Improving Clinician Knowledge and Confidence in Managing Complex Psychiatric Patients: a Waitlist-Controlled Study
Effectiveness of Project ECHO Programs in Improving Clinician Knowledge and Confidence in Managing Complex Psychiatric Patients: a Waitlist-Controlled Study Open
Objective The authors aimed to determine if Project Extension for Community Healthcare Outcomes (ECHO), a health-education model utilising teleconferencing technology, improves the capacity of clinicians in assessing and managing complex p…
View article: Developing and internally validating a prognostic model (P Risk) to improve the prediction of psychosis in a primary care population using electronic health records: The MAPPED study
Developing and internally validating a prognostic model (P Risk) to improve the prediction of psychosis in a primary care population using electronic health records: The MAPPED study Open
NIHR, School for Primary Care Research, Biomedical Research Centre.
View article: The cognitive, neural, and social aspects of regulatory mode and its implications on well-being and decision-making
The cognitive, neural, and social aspects of regulatory mode and its implications on well-being and decision-making Open
Regulatory mode theory distinguishes between two components, or modes, of effective self-regulation: locomotion and assessment. Locomotion refers to psychological state-to-state movement. Assessment refers to goal evaluation and means of g…
View article: Multi-disciplinary Evaluation of Sexual Assault Referral Centres (SARCs) for better Health (MESARCH): protocol for a 1-year cohort study examining health, well-being and cost outcomes in adult survivors of sexual assault attending SARCs in England
Multi-disciplinary Evaluation of Sexual Assault Referral Centres (SARCs) for better Health (MESARCH): protocol for a 1-year cohort study examining health, well-being and cost outcomes in adult survivors of sexual assault attending SARCs in England Open
Introduction Sexual violence is commonplace and has serious adverse consequences for physical and mental health. Sexual Assault Referral Centres (SARCs) are viewed as a best practice response. Little is known about their effectiveness and …
View article: Impact of e-cigarette retail displays on attitudes to smoking and vaping in children: an online experimental study
Impact of e-cigarette retail displays on attitudes to smoking and vaping in children: an online experimental study Open
Objectives To estimate the impact of electronic cigarette (e-cigarette) retail display exposure on attitudes to smoking and vaping (susceptibility to tobacco smoking and using e-cigarettes, and perceptions of the harms of smoking and e-cig…
View article: An intervention to improve teacher well-being support and training to support students in UK high schools (the WISE study): A cluster randomised controlled trial
An intervention to improve teacher well-being support and training to support students in UK high schools (the WISE study): A cluster randomised controlled trial Open
Background Teachers are at heightened risk of poor mental health and well-being, which is likely to impact on the support they provide to students, and student outcomes. We conducted a cluster randomised controlled trial, to test whether a…
View article: Mental health support and training to improve secondary school teachers’ well-being: the WISE cluster RCT
Mental health support and training to improve secondary school teachers’ well-being: the WISE cluster RCT Open
Background Health and Safety Executive data show that teachers are at heightened risk of mental health difficulties, yet few studies have attempted to address this. Poor teacher mental health may impact on the quality of support provided t…
View article: Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT
Immediate oral versus immediate topical versus delayed oral antibiotics for children with acute otitis media with discharge: the REST three-arm non-inferiority electronic platform-supported RCT Open
Background Acute otitis media is a painful infection of the middle ear that is commonly seen in children. In some children, the eardrum spontaneously bursts, discharging visible pus (otorrhoea) into the outer ear. Objective To compare the …
View article: Electronic cigarette and smoking paraphernalia point of sale displays: an observational study in England
Electronic cigarette and smoking paraphernalia point of sale displays: an observational study in England Open
Background Tobacco point of sale (POS) retail displays are banned in many countries, including in England, due in part to evidence linking them to greater susceptibility to smoking in children. There is no equivalent ban on displays of ele…
View article: Research Study Protocol: Using health information systems to address patients concerns in general practice: the COAC Intervention development and feasibility study
Research Study Protocol: Using health information systems to address patients concerns in general practice: the COAC Intervention development and feasibility study Open
Background Problems are missed in up to 50% of primary care consultations. This is costly for the NHS, both in terms of reconsultation rates and in missed opportunities to increase patient empowerment. Research suggests that interventions …
View article: P62 Educational inequalities in statin treatment: cross-sectional analysis of UK biobank
P62 Educational inequalities in statin treatment: cross-sectional analysis of UK biobank Open
Background Despite reductions in the rates of cardiovascular disease in high income countries, individuals who are the most socioeconomically deprived remain at the highest risk of disease. Although intermediate lifestyle and behavioural r…
View article: 145Educational inequalities in primary prevention statin use in UK Biobank
145Educational inequalities in primary prevention statin use in UK Biobank Open
Background Socioeconomic inequalities in cardiovascular disease are well documented, but the association of socioeconomic position with treatment for cardiovascular disease prevention is unclear. Methods Using data from a large prospective…
View article: Detecting Heterogeneity of Intervention Effects Using Analysis and Meta-analysis of Differences in Variance Between Trial Arms
Detecting Heterogeneity of Intervention Effects Using Analysis and Meta-analysis of Differences in Variance Between Trial Arms Open
Background: Randomized controlled trials (RCTs) with continuous outcomes usually only examine mean differences in response between trial arms. If the intervention has heterogeneous effects, then outcome variances will also differ between a…
View article: Effect of health warning labels on motivation towards energy-dense snack foods: Two experimental studies
Effect of health warning labels on motivation towards energy-dense snack foods: Two experimental studies Open
Health warning labels (HWLs) show promise in reducing motivation towards energy-dense snack foods. Understanding the underlying mechanisms could optimise their effectiveness. In two experimental studies in general population samples (Study…
View article: Lagged Association between Climate Variables and Hospital Admissions for Pneumonia in South Africa
Lagged Association between Climate Variables and Hospital Admissions for Pneumonia in South Africa Open
Pneumonia is a leading cause of hospitalization in South Africa. Climate change could potentially affect its incidence via changes in meteorological conditions. We investigated the delayed effects of temperature and relative humidity on pn…
View article: Equity-specific effects of interventions to promote physical activity among middle-aged and older adults: results from applying a novel equity-specific re-analysis strategy
Equity-specific effects of interventions to promote physical activity among middle-aged and older adults: results from applying a novel equity-specific re-analysis strategy Open
Background Reducing inequalities in physical activity (PA) and PA-associated health outcomes is a priority for public health. Interventions to promote PA may reduce inequalities, but may also unintentionally increase them. Thus, there is a…
View article: Health warning labels and alcohol selection: a randomised controlled experiment in a naturalistic shopping laboratory
Health warning labels and alcohol selection: a randomised controlled experiment in a naturalistic shopping laboratory Open
Background and aims Health warning labels (HWLs) on tobacco products reduce smoking. There is an absence of evidence concerning the impact of alcohol HWLs on selection or purchasing in naturalistic settings. Using a commercial‐standard nat…
View article: Investigating the Use of Electronic Well-being Diaries Completed Within a Psychoeducation Program for University Students: Longitudinal Text Analysis Study
Investigating the Use of Electronic Well-being Diaries Completed Within a Psychoeducation Program for University Students: Longitudinal Text Analysis Study Open
Background Psychoeducation has the potential to support students experiencing distress and help meet the demand for support; however, there is a need to understand how these programs are experienced. Web-based diaries are a useful activity…
View article: Cigarette pack size and consumption: an adaptive randomised controlled trial
Cigarette pack size and consumption: an adaptive randomised controlled trial Open
BackgroundObservational evidence suggests that cigarette pack size – the number of cigarettes in a single pack – is associated with consumption but experimental evidence of a causal relationship is lacking. The tobacco industry is introduc…