W. Reith
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View article: Safety, Technical and Clinical Success of the Aperio Hybrid Thrombectomy Device in Acute Ischemic Stroke, a Prospective Post-market Clinical Follow-up Study (HYBRID)
Safety, Technical and Clinical Success of the Aperio Hybrid Thrombectomy Device in Acute Ischemic Stroke, a Prospective Post-market Clinical Follow-up Study (HYBRID) Open
Purpose Stentretrievers are key devices for endovascular treatment of acute ischemic stroke. Aim of this post market clinical follow-up study was to asses safety and outcomes of interventions using the APERIO® Hybrid/Hybrid 17|21 thrombect…
Curved trajectories in stereotactic neurosurgery using continuum robots: first steps towards feasibility Open
Objective Stereotactic procedures are planned and performed with straight trajectories. However, brain sulci with vessels and ventricles have to be avoided for bleeding and deviation risks. In distinct pathologies such as insular or pineal…
ACTIVITY IN HUMAN DORSAL RAPHE NUCLEUS SIGNALS CHANGES IN BEHAVIOURAL POLICY Open
The dorsal raphe nucleus (DRN) is an important source of serotonin to the human forebrain, however there is little consensus about its behavioural function. We build on recent results from animal models to demonstrate that activity in huma…
Evaluation of a novel polymer coil for endovascular occlusion of intracranial aneurysms in a rabbit model Open
Background and Purpose The results of the preclinical study of a novel polymer coil in treatment of elastase induced aneurysms will be presented in this paper. Material and Methods We induced 16 aneurysms in 16 New Zealand white rabbits at…
Recurrent reversible in-stent-stenosis after flow diverter treatment Open
Flow diverter stents (FDS) are well established in the treatment of intracranial aneurysms which are difficult to treat with conventional endovascular techniques. However, they carry a relatively high risk of specific complications compare…
View article: Learning Curve for Flow Diversion of Posterior Circulation Aneurysms: A Long-Term International Multicenter Cohort Study
Learning Curve for Flow Diversion of Posterior Circulation Aneurysms: A Long-Term International Multicenter Cohort Study Open
This multicenter experience revealed a trend toward treating fewer basilar aneurysms, smaller aneurysms, and increased usage of a single flow diverter, leading to a decrease in the rate of thromboembolic and hemorrhagic complications.
Cranial MRI in Childhood Acute Leukemia during Treatment and Follow-Up Including the Impact of Intrathecal MTX—A Single-Center Study and Review of the Literature Open
Due to high survival rates, long-term sequelae, especially neurotoxicity, need to be considered in childhood acute leukemias. In this retrospective analysis of morphologic changes of the brain in children treated for acute leukemias, we in…
Schwannoma of the Hypoglossal Nerve Mimicking Carotid Body Paraganglioma Open
Carotid body paragangliomas (CBPs) clinically present as highly vascularized cervical masses with a pathognomonic localization at the carotid artery bifurcation. Following ultrasonography and MRI/CT imaging, surgical resection with optiona…
Long-term follow-up MRI shows no hastening of adjacent segment degeneration following cervical disc arthroplasty Open
Cervical disc arthroplasty is an established procedure, but studies with data on long-term clinical outcome, reoperation for symptomatic adjacent segment degeneration (sASD), and degenerative changes based on MRI findings are rare. Thus, a…
Transorbital embolization of cavernous sinus dural arterio-venous malformations with surgical exposure and catheterization of the superior ophthalmic vein Open
Purpose Cavernous sinus dural arterio-venous malformations (dAVF) represent a pathologic connection between branches of the internal and/or external carotid artery and the cavernous sinus. Standard endovascular approaches for dAVF treatmen…
Endovascular treatment of unruptured intracranial aneurysms with flow diverters: A retrospective long-term single center analysis Open
Purpose The introduction of flow diverters (FDs) in 2007 greatly enhanced the treatment of intracranial aneurysms. Here, we present our long-term clinical experience in treating unruptured intracranial aneurysms with FDs. Methods 107 patie…
Vascular Response on a Novel Fibrin-Based Coated Flow Diverter Open
Purpose Due to thromboembolic complications and in-stent-stenosis after flow diverter (FD) treatment, the long-term use of dual antiplatelet treatment (DAPT) is mandatory. The tested nano-coating has been shown to reduce material thromboge…
Retrospective analysis of intracranial aneurysms after flow diverter treatment including color-coded imaging (syngo iFlow) as a predictor of aneurysm occlusion Open
Purpose Flow Diverters (FD) have immensely extended the treatment of cerebral aneurysms in the past years. Complete aneurysm occlusion is a process that often takes a certain amount of time and is usually difficult to predict. Our aim was …
Treatment of experimental aneurysms with a GPX embolic agent prototype: preliminary angiographic and histological results Open
Background Recently, liquid embolic agents have emerged for the endovascular treatment of cerebral aneurysms. Here we describe the in vivo performance of a novel liquid embolization agent (GPX Embolic Device). Methods Elastase-induced aneu…
The Individual Inclination to an Occupation and its Neuronal Correlate Open
Many young people decide their professional direction during adolescence. This often coincides with vulnerable phases of puberty-related maturation that is usually accompanied by difficulties in assessing one’s personal inclinations and co…
Correction to: In vivo comparison of braided (Accero) and laser-cut intracranial stents (Acclino, Credo): evaluation of vessel responses at subacute and mid-term follow-up in a rabbit model Open
A Correction to this paper has been published: https://doi.org/10.1007/s10856-021-06518-6
View article: Derivo embolization device in the treatment of unruptured intracranial aneurysms: a prospective multicenter study
Derivo embolization device in the treatment of unruptured intracranial aneurysms: a prospective multicenter study Open
Background Flow diverters (FD) are used regularly for the endovascular treatment of unruptured intracranial aneurysms. We aimed to assess the safety and effectiveness of the Derivo embolization device (DED) with respect to long-term clinic…
View article: Gastric Motility in Parkinson’s Disease is Altered Depending on the Digestive Phase and Does Not Correlate with Patient-Reported Motor Fluctuations
Gastric Motility in Parkinson’s Disease is Altered Depending on the Digestive Phase and Does Not Correlate with Patient-Reported Motor Fluctuations Open
Background: Altered gastric motility is a frequent non-motor symptom of Parkinson’s disease (PD). It has been hypothesized that disturbed gastric motility contributes to motor fluctuations in PD due to an erratic gastro-duodenal transport …
Decline of emergency admissions for cardiovascular and cerebrovascular events after the outbreak of COVID-19 Open
Background The spread of the novel coronavirus SARS-CoV-2 and the guidance from authorities for social distancing and media reporting lead to significant uncertainty in Germany. As concerns have been expressed regarding the underdiagnosing…
Embolisation of sinus cavernosus fistulas via transorbital approach of the ophtalmic vein Open
Background The Sinus cavernosus fistula is a vascular malformation, meaning an abnormal connection between the arteria carotis interna or externa with the sinus cavernosus. Established Methods to obturate such fistulas are at the moment th…
Rescue of migrated Woven Endobridge devices using a stent-retriever-technique in a porcine model Open
Purpose The Woven Endobridge device (WEB) has become widely applied for the treatment of intracranial aneurysms. Complications are rare, however, especially dislocations and migrations can potentially increase poor clinical outcome. The ai…
View article: The FRED for Cerebral Aneurysms of the Posterior Circulation: A Subgroup Analysis of the EuFRED Registry
The FRED for Cerebral Aneurysms of the Posterior Circulation: A Subgroup Analysis of the EuFRED Registry Open
The largest cohort of posterior circulation aneurysms treated with the FRED to date demonstrated favorable safety and efficacy profiles of the device for this indication. Treatment in the setting of acute subarachnoid hemorrhage was strong…