Wei Zhan
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View article: First development of a 100 K SNP array for small yellow croaker and its application in genomic selection for growth and disease resistance
First development of a 100 K SNP array for small yellow croaker and its application in genomic selection for growth and disease resistance Open
View article: Analysis and comparison of the trends in the burden of migraine in China and globally from 1990 to 2021, with a forecast to 2031
Analysis and comparison of the trends in the burden of migraine in China and globally from 1990 to 2021, with a forecast to 2031 Open
Background Migraine is a prevalent neurological disorder in China and globally, imposing significant burdens on individuals and societies. The goal of this study was to characterize age- and sex-specific temporal patterns in migraine burde…
View article: Short-chain fatty acids affect skeletal muscle composition, fiber recruitment, and metabolism of the small yellow croaker (Larimichthys polyactis)
Short-chain fatty acids affect skeletal muscle composition, fiber recruitment, and metabolism of the small yellow croaker (Larimichthys polyactis) Open
Recent studies have revealed that intestinal short-chain fatty acids (SCFAs) can affect muscles muscle metabolism in mammals by promoting glycogen metabolism and lipid oxidation. It is still not clear the distinct effect of acetate, propio…
View article: Prognostic Value of Life’s Essential 8 for Multiple Disease Mortality in a Southwestern Chinese Cohort: A Novel Application of AFT and PAF Models
Prognostic Value of Life’s Essential 8 for Multiple Disease Mortality in a Southwestern Chinese Cohort: A Novel Application of AFT and PAF Models Open
Background: To investigate Life’s Essential 8(LE8) , a measure of cardiovascular health (CVH),and itsassociation with all-cause and disease-specific mortality. Methods: CVH and LE8 were categorized into 0-49 (low), 50-74 (moderate), and 75…
View article: Movement Mechanisms Harness Lévy Flight for Energy‐Efficient Wastewater Treatment in Microalgae–Bacteria Systems
Movement Mechanisms Harness Lévy Flight for Energy‐Efficient Wastewater Treatment in Microalgae–Bacteria Systems Open
Microalgae–bacteria symbiosis system is significant for sustainable and low‐carbon wastewater treatment, with self‐aggregation being key to its stable operation and effective pollutant removal. Cellular motility is the main driving force b…
View article: Physical information entropy-driven performance deterioration diagnosis for control systems of coal power plant
Physical information entropy-driven performance deterioration diagnosis for control systems of coal power plant Open
This article primarily focuses on addressing the problem of performance deterioration diagnosis for coal power plant control systems. First, a digital twin dynamics model of real industrial control systems driven by physical state variable…
View article: Comparative Analysis of DVT Incidence After Posterior Lumbar Interbody Fusion（PLIF）and percutaneous endoscopic lumbar interbody fusion (PELIF): Identifying Risk Factors and Developing a Predictive Model
Comparative Analysis of DVT Incidence After Posterior Lumbar Interbody Fusion（PLIF）and percutaneous endoscopic lumbar interbody fusion (PELIF): Identifying Risk Factors and Developing a Predictive Model Open
Objective: This study aims to compare the incidence of deep vein thrombosis (DVT) between patients undergoing Posterior Lumbar Interbody Fusion（PLIF）and percutaneous endoscopic lumbar interbody fusion (PELIF) , identify independent risk fa…
View article: Resilient Leadership and SME Performance in Times of Crisis: The Mediating Roles of Temporal Psychological Capital and Innovative Behavior
Resilient Leadership and SME Performance in Times of Crisis: The Mediating Roles of Temporal Psychological Capital and Innovative Behavior Open
Small and medium-sized enterprises (SMEs) often face severe resource constraints and operational fragility during crises. However, little is known about how managerial resilience (MR) translates into performance through time-related psycho…
View article: MolGlueDB: an online database of molecular glues
MolGlueDB: an online database of molecular glues Open
Molecular glue degraders (MGDs) and proteolysis-targeting chimeras (PROTACs) are two prominent approaches in targeted protein degradation, both leveraging the ubiquitin-proteasome system to induce selective protein degradation. While PROTA…
View article: FGFR1-amplified colorectal cancer: a distinct prognostic subtype identified through integrated genomic and immunohistochemical profiling
FGFR1-amplified colorectal cancer: a distinct prognostic subtype identified through integrated genomic and immunohistochemical profiling Open
This study provides the first comprehensive characterization of FGFR genomic alterations in CRC through large-scale profiling (n = 7606), establishing FGFR1 amplification as the predominant alteration. Unlike FGFR2/3-driven malignancies, F…
View article: The Impact of Intelligent Medical Systems Combined with Interdisciplinary Care Teams on Home-Based Elderly Population’s Quality of Life
The Impact of Intelligent Medical Systems Combined with Interdisciplinary Care Teams on Home-Based Elderly Population’s Quality of Life Open
The intelligent care model proves effective in enhancing functional capacity and reducing care dependency among homebound elderly, offering valuable insights for elderly care service optimization. Further research should explore long-term …
View article: Effects of monochromatic light on eye growth regulation and Myopia control
Effects of monochromatic light on eye growth regulation and Myopia control Open
View article: The difference of variation types between late-onset multiple acyl-CoA dehydrogenase deficiency patients carrying biallelic and single heterozygous variations in ETFDH: a systematic review and meta-analysis
The difference of variation types between late-onset multiple acyl-CoA dehydrogenase deficiency patients carrying biallelic and single heterozygous variations in ETFDH: a systematic review and meta-analysis Open
Background Late-onset multiple acyl-CoA dehydrogenase deficiency (MADD) is an autosomal recessive disease chiefly caused by mutations in ETFDH gene. Mutations in the ETFDH gene lead to abnormal structure, impaired function, and increased d…
View article: Shifting regional development scenarios amplify legacy phosphorus threats to water quality
Shifting regional development scenarios amplify legacy phosphorus threats to water quality Open
Legacy phosphorus, accumulated from past anthropogenic activities, poses persistent and complex threats to global water quality. Despite extensive efforts to control phosphorus inputs, legacy phosphorus can persist for decades and undermin…
View article: Chromosome-level genome assembly of the synanthropic fly Chrysomya megacephala: insights into oviposition location
Chromosome-level genome assembly of the synanthropic fly Chrysomya megacephala: insights into oviposition location Open
The oriental latrine fly, Chrysomya megacephala (Diptera: Calliphoridae), is a medically important synanthropic blow fly species characterized by its necrophagy and coprophagy, often observed near carrion and animal feces. Notably, C. mega…
View article: The dissection of genotype × tissue interactions in mud crab Scylla paramamosain indicates the sexual differences in parental selection
The dissection of genotype × tissue interactions in mud crab Scylla paramamosain indicates the sexual differences in parental selection Open
Studying the impact of genotype, tissue type, and their interaction on key sexual factor expression provides valuable insights into the spectrum and consequence of sex differences, particularly for maternal and paternal selection in the br…
View article: Study on Dynamic Response of Saturated Asphalt Pavement Under Multi Factor Interaction
Study on Dynamic Response of Saturated Asphalt Pavement Under Multi Factor Interaction Open
In order to solve the water damage phenomenon of asphalt pavement in humid, hot and rainy areas, the mechanism of dynamic water pressure on asphalt pavement was studied. Firstly, a model of the relationship between frequency, air void, per…
View article: High-Throughput Computation of ab initio Raman Spectra for Two-Dimensional Materials
High-Throughput Computation of ab initio Raman Spectra for Two-Dimensional Materials Open
Raman spectra play an important role in characterizing two-dimensional materials, as they provide a direct link between the atomic structure and the spectral features. In this work, we present an automatic computational workflow for Raman …
View article: Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster
Molecular mechanism on autophagy associated cardiovascular dysfunction in Drosophila melanogaster Open
As a highly conserved cellular process, autophagy has been the focus of extensive research due to its critical role in maintaining cellular homeostasis and its implications in cardiovascular pathogenesis. The decline in muscular function, …
View article: Measuring Intra-Urban Innovation Space from the Unit-Network Perspective: A Case Study of Guangzhou
Measuring Intra-Urban Innovation Space from the Unit-Network Perspective: A Case Study of Guangzhou Open
Three spatial turns have occurred in innovation research, including focuses on regional, urban, and intra-urban scales. The primary focus of this study was to determine the spatial distribution of innovation and the innovation networks wit…
View article: Extracellular vesicle-mediated gene therapy targets BRAFV600E-mutant colorectal cancer by inhibiting the MEK1/2-ERK1/2 pathway
Extracellular vesicle-mediated gene therapy targets BRAFV600E-mutant colorectal cancer by inhibiting the MEK1/2-ERK1/2 pathway Open
The therapeutic EVs we constructed are effective and specific for the BRAFV600E-mutant CRC. This study provides a novel strategy for the treatment of CRC patients with BRAFV600E mutation.
View article: Impact of metakaolin to partially replace granulated blast furnace slag on the performance of alkali-activated slag grouting materials and evaluation of grouting effectiveness
Impact of metakaolin to partially replace granulated blast furnace slag on the performance of alkali-activated slag grouting materials and evaluation of grouting effectiveness Open
In recent years, alkali-activated slag materials have garnered widespread attention in the construction field due to their environmental friendliness and excellent mechanical strength. However, optimizing their composition to reduce autoge…
View article: Acellular and Cellular Health Implications of Wintertime Fine Particulate Matter from Southwestern China
Acellular and Cellular Health Implications of Wintertime Fine Particulate Matter from Southwestern China Open
View article: Short-Chain Fatty Acids Affect Skeletal Muscle Composition, Fiber Recruitment, and Metabolism of the Small Yellow Croaker (Larimichthys Polyactis)
Short-Chain Fatty Acids Affect Skeletal Muscle Composition, Fiber Recruitment, and Metabolism of the Small Yellow Croaker (Larimichthys Polyactis) Open
View article: Hierarchically Engineered Ti-Fe Prussian Blue Analogue Membranes with Photocatalytic Regeneration for Ultra-Selective Thallium(I) Trapping in Real Water Matrices
Hierarchically Engineered Ti-Fe Prussian Blue Analogue Membranes with Photocatalytic Regeneration for Ultra-Selective Thallium(I) Trapping in Real Water Matrices Open
View article: Β-Feooh Modified Polyurethane Foam for Efficient Adsorption of Arsenite and Arsenate from Contaminated Water
Β-Feooh Modified Polyurethane Foam for Efficient Adsorption of Arsenite and Arsenate from Contaminated Water Open
View article: Short-chain fatty acids affect skeletal muscle composition, fiber recruitment, and metabolism of the small yellow croaker (Larimichthys polyactis)
Short-chain fatty acids affect skeletal muscle composition, fiber recruitment, and metabolism of the small yellow croaker (Larimichthys polyactis) Open
View article: Short-Chain Fatty Acids Affect Skeletal Muscle Composition, Fiber Recruitment, and Metabolism of the Small Yellow Croaker (Larimichthys Polyactis)
Short-Chain Fatty Acids Affect Skeletal Muscle Composition, Fiber Recruitment, and Metabolism of the Small Yellow Croaker (Larimichthys Polyactis) Open
View article: MYB represses ζ-globin expression through upregulating ETO2
MYB represses ζ-globin expression through upregulating ETO2 Open
Reactivating the embryonic ζ-globin gene represents a potential therapeutic approach to ameliorate the severe clinical phenotype of α-thalassemia and sickle cell disease. The transcription factor MYB has been extensively proven to be a mas…
View article: Driv3R: Learning Dense 4D Reconstruction for Autonomous Driving
Driv3R: Learning Dense 4D Reconstruction for Autonomous Driving Open
Realtime 4D reconstruction for dynamic scenes remains a crucial challenge for autonomous driving perception. Most existing methods rely on depth estimation through self-supervision or multi-modality sensor fusion. In this paper, we propose…