Wahram Andrikyan
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View article: Physicians' and pharmacists' perspective on clarity and clinical relevance of absolute contraindications in “Summaries of Product Characteristics”
Physicians' and pharmacists' perspective on clarity and clinical relevance of absolute contraindications in “Summaries of Product Characteristics” Open
Aims Previous work has identified several limitations in “Summaries of Product Characteristics” (SmPCs), which are associated with risks for patients. The aim of this study was to evaluate pharmacists' and physicians' interpretation of con…
View article: Artificial intelligence-powered chatbots in search engines: a cross-sectional study on the quality and risks of drug information for patients
Artificial intelligence-powered chatbots in search engines: a cross-sectional study on the quality and risks of drug information for patients Open
Background Search engines often serve as a primary resource for patients to obtain drug information. However, the search engine market is rapidly changing due to the introduction of artificial intelligence (AI)-powered chatbots. The conseq…
View article: Detection of elevated risk for drug-related problems in the hospital
Detection of elevated risk for drug-related problems in the hospital Open
View article: Pseudo‐Worsening of Kidney Function Due to Inhibition of Renal Creatinine Secretion: Quality of Information Provided in Prescribing Information/<scp>SmPC</scp>
Pseudo‐Worsening of Kidney Function Due to Inhibition of Renal Creatinine Secretion: Quality of Information Provided in Prescribing Information/<span>SmPC</span> Open
Determination of serum creatinine concentrations and subsequent calculation of estimated glomerular filtration rates (eGFR) is a cornerstone of clinical medicine. Crucial clinical decisions such as drug treatment discontinuations are based…
View article: INTERPOLAR – prospektive, interventionelle Studien im Rahmen der Medizininformatik-Initiative zur Verbesserung der Arzneimitteltherapiesicherheit in der Krankenversorgung
INTERPOLAR – prospektive, interventionelle Studien im Rahmen der Medizininformatik-Initiative zur Verbesserung der Arzneimitteltherapiesicherheit in der Krankenversorgung Open
Zusammenfassung Medikationsanalysen durch Stationsapotheker:innen sind eine wichtige Maßnahme der Arzneimitteltherapiesicherheit (AMTS). Dabei werden medikationsbezogene Probleme (Medication Related Problems [MRPs]) identifiziert und zusam…
View article: Inconsistencies of absolute drug–drug contraindication reports: Analysis of Summaries of Product Characteristics of commonly prescribed drugs
Inconsistencies of absolute drug–drug contraindication reports: Analysis of Summaries of Product Characteristics of commonly prescribed drugs Open
Aims Prescribing information should follow a defined structure to help prescribers easily find required information. Often information appears in different sections of Summaries of Product Characteristics (SmPCs) in an inconsistent way. St…
View article: Documentation of Drug-Related Problems with ICD-11: Application of the New WHO Code-Set to Clinical Routine Data
Documentation of Drug-Related Problems with ICD-11: Application of the New WHO Code-Set to Clinical Routine Data Open
Drug-related problems (DRPs), i.e., adverse drug reactions (ADRs) and medication errors (MEs), constitute a serious threat to the patient’s safety. DRPs are often insufficiently captured by clinical routine documentation, and thus, they fr…
View article: POLAR – „POLypharmazie, Arzneimittelwechselwirkungen und Risiken“ – wie können Daten aus der stationären Krankenversorgung zur Beurteilung beitragen?
POLAR – „POLypharmazie, Arzneimittelwechselwirkungen und Risiken“ – wie können Daten aus der stationären Krankenversorgung zur Beurteilung beitragen? Open
Zusammenfassung Hintergrund Mit der zunehmenden Anzahl eingenommener Arzneimittel steigt die Prävalenz von Medikationsrisiken. Hierzu zählen beispielsweise Arzneimittelwechselwirkungen, welche erwünschte und unerwünschte Wirkungen einzelne…
View article: Use of medication data alone to identify diagnoses and related contraindications: Application of algorithms to close a common documentation gap
Use of medication data alone to identify diagnoses and related contraindications: Application of algorithms to close a common documentation gap Open
Aims Automated checks for medication‐related problems have become a cornerstone of medication safety. In many clinical settings medication checks remain confined to drug–drug interactions because only medication data are available in an ad…
View article: Comprehensibility of Contraindications in German, UK and US Summaries of Product Characteristics/Prescribing Information—A Comparative Qualitative and Quantitative Analysis
Comprehensibility of Contraindications in German, UK and US Summaries of Product Characteristics/Prescribing Information—A Comparative Qualitative and Quantitative Analysis Open
Contraindications (CIs) in Summaries of Product Characteristics (SmPCs)/Prescribing Information (PI) that lack clarity may pose a risk to medication safety and increase the risk for adverse drug reactions. We assessed and compared SmPCs/PI…
View article: The CredibleMeds<sup>®</sup> list: Usage of QT interval prolonging drugs in Germany and discordances with prescribing information
The CredibleMeds<sup>®</sup> list: Usage of QT interval prolonging drugs in Germany and discordances with prescribing information Open
Aims A substantial number of Summaries of Product Characteristics (SmPCs)/Prescribing Information (PI) have warnings or contraindications on QT interval prolongation. The goal of this work was to quantify usage of QT interval prolonging dr…