Wahyu Wijaya Hadiwikarta
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View article: A Unified Single-Cell Atlas of HNSCC: Uncovering HPV and Sex Variability in the Tumor Microenvironment
A Unified Single-Cell Atlas of HNSCC: Uncovering HPV and Sex Variability in the Tumor Microenvironment Open
Head and neck squamous cell carcinoma (HNSCC) is highly heterogeneous, with variations driven by HPV status and sex. However, existing single-cell RNA sequencing (scRNA-seq) studies are often limited in sample size and lack standardized me…
View article: Semantic Representation of Preclinical Data in Radiation Oncology.
Semantic Representation of Preclinical Data in Radiation Oncology. Open
Background: In radiation oncology, the data generated from preclinical trials serve as initial validation for treatment effectiveness and optimizing clinical approaches by unraveling molecular mechanisms underlying different treatment resp…
View article: Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer
Epigenetic Targeting to Overcome Radioresistance in Head and Neck Cancer Open
(1) Background: The sensitivity of head and neck squamous cell carcinoma (HNSCC) to ionizing radiation, among others, is determined by the number of cells with high clonogenic potential and stem-like features. These cellular characteristic…
View article: The Role of SOX2 and SOX9 in Radioresistance and Tumor Recurrence
The Role of SOX2 and SOX9 in Radioresistance and Tumor Recurrence Open
Head and neck squamous cell carcinoma (HNSCC) exhibits considerable variability in patient outcome. It has been reported that SOX2 plays a role in proliferation, tumor growth, drug resistance, and metastasis in a variety of cancer types. A…
View article: Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity Open
Proton radiotherapy has been implemented into the standard-of-care for cancer patients within recent years. However, experimental studies investigating cellular and molecular mechanisms are lacking, and prognostic biomarkers are needed. Ca…
View article: Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: A multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG)
Evaluation of prognostic factors after primary chemoradiotherapy of anal cancer: A multicenter study of the German Cancer Consortium-Radiation Oncology Group (DKTK-ROG) Open
View article: 2021-10-05 Lecture JUB
2021-10-05 Lecture JUB Open
Lecture slide of "Current Topics in Data Engineering Colloquium", JUB, 5 October 2021
View article: Thermodynamic framework to assess low abundance DNA mutation detection by hybridization
Thermodynamic framework to assess low abundance DNA mutation detection by hybridization Open
The knowledge of genomic DNA variations in patient samples has a high and increasing value for human diagnostics in its broadest sense. Although many methods and sensors to detect or quantify these variations are available or under develop…
View article: Transient loading of CD34<sup>+</sup>&nbsp;hematopoietic progenitor cells with polystyrene nanoparticles
Transient loading of CD34<sup>+</sup> hematopoietic progenitor cells with polystyrene nanoparticles Open
CD34+ hematopoietic progenitor cells (HPCs) offer great opportunities to develop new treatments for numerous malignant and non-malignant diseases. Nanoparticle (NP)-based strategies can further enhance this potential, and theref…
View article: CONSTANd : A Normalization Method for Isobaric Labeled Spectra by Constrained Optimization
CONSTANd : A Normalization Method for Isobaric Labeled Spectra by Constrained Optimization Open