Walaa H. Moustafa
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View article: Downregulation of Klebsiella pneumoniae RND efflux pump following indole signal produced by Escherichia coli
Downregulation of Klebsiella pneumoniae RND efflux pump following indole signal produced by Escherichia coli Open
Background More than a century has passed since it was discovered that many bacteria produce indole, but research into the actual biological roles of this molecule is just now beginning. The influence of indole on bacterial virulence was e…
View article: Prevalence and Antibiotic Resistance Patterns of Multidrug-Resistant (MDR) Bacteria Isolated from Pediatric Intensive Care Units
Prevalence and Antibiotic Resistance Patterns of Multidrug-Resistant (MDR) Bacteria Isolated from Pediatric Intensive Care Units Open
Background: The escalating prevalence of antibiotic-resistant organisms, coupled with limited discovery efforts of novel drugs, poses a critical challenge. Particularly pediatrics are at an elevated risk, making periodic updates on antibio…
View article: Design, Synthesis, In Vitro, and In Silico Studies of New N5-Substituted-pyrazolo[3,4-d]pyrimidinone Derivatives as Anticancer CDK2 Inhibitors
Design, Synthesis, In Vitro, and In Silico Studies of New N5-Substituted-pyrazolo[3,4-d]pyrimidinone Derivatives as Anticancer CDK2 Inhibitors Open
CDK2 is a key player in cell cycle processes. It has a crucial role in the progression of various cancers. Hepatocellular carcinoma (HCC) and colorectal cancer (CRC) are two common cancers that affect humans worldwide. The available therap…
View article: Assessing Women’s Knowledge and Practice Regarding Urinary Incontinence and Pelvic Floor Muscles Exercises
Assessing Women’s Knowledge and Practice Regarding Urinary Incontinence and Pelvic Floor Muscles Exercises Open
Background: Urinary incontinence is a serious problem that deteriorate women's life at any age specially if neglected.However, there are many actions to solve this problem the most important is pelvic floor muscles exercises which is regis…
View article: Comparative Analysis of Human and Animal E. coli: Serotyping, Antimicrobial Resistance, and Virulence Gene Profiling
Comparative Analysis of Human and Animal E. coli: Serotyping, Antimicrobial Resistance, and Virulence Gene Profiling Open
Widespread multidrug-resistant (MDR) and multi-virulent diarrheagenic E. coli create several crises among human and animal populations worldwide. For this reason, we looked forward to a breakthrough with this issue and tried to highlight t…
View article: Clostridium perfringens Associated with Foodborne Infections of Animal Origins: Insights into Prevalence, Antimicrobial Resistance, Toxin Genes Profiles, and Toxinotypes
Clostridium perfringens Associated with Foodborne Infections of Animal Origins: Insights into Prevalence, Antimicrobial Resistance, Toxin Genes Profiles, and Toxinotypes Open
Several food-poisoning outbreaks have been attributed to Clostridium perfringens (C. perfringens) worldwide. Despite that, this crisis was discussed in a few studies, and additional studies are urgently needed in this field. Therefore, we …
View article: Expression of Tyrosinase, Tyrp1 and Tyrp2 in vitiligo
Expression of Tyrosinase, Tyrp1 and Tyrp2 in vitiligo Open
Vitiligo, an acquired idiopathic pigmentary disorder of skin and hair, is characterized by wellcircumscribed asymptomatic white cutaneous macules and patches, where selective destruction of functioning melanocytes.Tyrosinase (TYR) gene fam…
View article: Detection of blaSPM-1 and blaSIM-2 Metallo-β-Lactamases Genes in Imipenem-Resistant Pseudomonas aeruginosa Clinical Isolates Recovered from Two University Hospitals in Egypt
Detection of blaSPM-1 and blaSIM-2 Metallo-β-Lactamases Genes in Imipenem-Resistant Pseudomonas aeruginosa Clinical Isolates Recovered from Two University Hospitals in Egypt Open
Objectives: Unraveling mechanisms whereby Pseudomonas aeruginosa becomes resistant to carbapenems through testing 114 non-duplicate P. aeruginosa clinical isolates for their susceptibility to various classes of antibiotics and scrutinizing…