Karim Yaqub Ibrahim
YOU?
Author Swipe
View article: Advancing HIV and Cancer Research: Implementing an AIDS and Cancer Specimen Resource in Latin America
Advancing HIV and Cancer Research: Implementing an AIDS and Cancer Specimen Resource in Latin America Open
The AIDS and Cancer Specimen Resource (ACSR) has developed a global biorepository network to support research on AIDS-defining and non-AIDS-defining cancers. This article details the establishment of a dedicated HIV-associated cancer biore…
View article: Anal cancer impact among people with HIV infection – a matched cohort study
Anal cancer impact among people with HIV infection – a matched cohort study Open
Anal carcinoma HIV+ patients treated with CRT presented similar cCR, RFS and OS compared with HIV- patients. Optimal therapy should be attempted in the HIV+ population; however, close clinical monitoring due to higher hospital admission is…
View article: Human immunodeficiency virus pretreatment drug resistance to first line antiretroviral therapy: a single center study
Human immunodeficiency virus pretreatment drug resistance to first line antiretroviral therapy: a single center study Open
Background Human immunodeficiency virus (HIV) infection is a worldwide health problem that contributes to hundreds of thousands of deaths each year. In Egypt, all infected people are offered treatment on diagnosis, free of charge, regardle…
View article: Retroperitoneal Ewing Sarcoma among Asian Patients: A Case Report and Review of Literature
Retroperitoneal Ewing Sarcoma among Asian Patients: A Case Report and Review of Literature Open
Retroperitoneal Extraosseous Ewing Sarcoma (EES) is a rare malignancy and poses diagnostic and management challenges. We present a case report of a 32-year-old Malay male who experienced persistent abdominal distension with constitutional …
View article: Safety of two-dose schedule of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan) and heterologous additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised and immunocompetent individuals
Safety of two-dose schedule of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan) and heterologous additional doses of mRNA BNT162b2 (Pfizer/BioNTech) in immunocompromised and immunocompetent individuals Open
Immunocompromised individuals were considered high-risk for severe disease due to SARS COV-2 infection. This study aimed to describe the safety of two doses of COVID-19 adsorbed inactivated vaccine (CoronaVac; Sinovac/Butantan), followed b…
View article: Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint Open
The aminopeptidase, endoplasmic reticulum aminopeptidase 1 (ERAP1), trims peptides for loading into major histocompatibility complex class I (MHC class I), and loss of this activity has broad effects on the MHC class I peptidome. Here, we …
View article: Efficacy and Safety of Chemoradiation with Cisplatin plus Capecitabine in Localized Squamous Cell Anal Cancer
Efficacy and Safety of Chemoradiation with Cisplatin plus Capecitabine in Localized Squamous Cell Anal Cancer Open
Background Localized Squamous Cell Anal Cancer (SCCAC) is a rare disease. The standard of care treatment with curative intent is chemoradiation (CRT) with mitomycin (MMC) or cisplatin (CDDP) plus infusional 5-Fluoracil (5-FU). Capecitabine…
View article: Septic paravertebral abscess and inferior vena cava thrombosis complicated by uro-sepsis: Case report
Septic paravertebral abscess and inferior vena cava thrombosis complicated by uro-sepsis: Case report Open
Paravertebral abscess is an uncommon and potentially dangerous illness characterized by the buildup of pus in the anatomical area surrounding the spinal column. A 65-year-old female, who has diabetes and high blood pressure, came in with i…
View article: Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons
Immunogenicity of COVID-19 adsorbed inactivated vaccine (CoronaVac) and additional doses of mRNA BNT162b2 vaccine in immunocompromised adults compared with immunocompetent persons Open
Inactivated COVID-19 vaccines data in immunocompromised individuals are scarce. This trial assessed the immunogenicity of two CoronaVac doses and additional BNT162b2 mRNA vaccine doses in immunocompromised (IC) and immunocompetent (H) indi…
View article: Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer
Validation of the North America expert consensus statement on reporting CT findings for COVID-19 in individuals with lung cancer Open
The aim of our study was to validate the use of the standardized Radiological Society of North America (RSNA) reporting system in individuals with known lung cancer who presented to the emergency department with suspected COVID-19. We incl…
View article: Facilitating access to pneumococcal vaccine for people living with HIV: an experience report
Facilitating access to pneumococcal vaccine for people living with HIV: an experience report Open
The article describes a strategy to facilitate access to pneumococcal conjugate vaccine 13 (PCV-13) for people living with HIV/AIDS (PLHIV) during the COVID-19 pandemic. Method: report on the experience regarding the organization of a care…
View article: Clinical presentation and in-hospital prognosis of lung cancer patients presenting with suspected and confirmed COVID-19
Clinical presentation and in-hospital prognosis of lung cancer patients presenting with suspected and confirmed COVID-19 Open
We sought to compare the clinical presentation and prognosis of patients with lung cancer and confirmed COVID-19 infection to those with negative RT-PCR SARS-CoV-2 results. We included patients with confirmed lung cancer and suspected COVI…
View article: Adverse events following yellow fever vaccination in immunocompromised persons
Adverse events following yellow fever vaccination in immunocompromised persons Open
This observational retrospective study conducted during an yellow fever (YF) outbreak in Sao Paulo, Brazil, in 2017-2018, describes adverse events (AE) following YF vaccination of immunocompromised persons. Risks and benefits of vaccinatio…
View article: Impact of antibiotic resistance on outcomes of neutropenic cancer patients with <i>Pseudomonas aeruginosa</i> bacteraemia (IRONIC study): study protocol of a retrospective multicentre international study
Impact of antibiotic resistance on outcomes of neutropenic cancer patients with <i>Pseudomonas aeruginosa</i> bacteraemia (IRONIC study): study protocol of a retrospective multicentre international study Open
Introduction Pseudomonas aeruginosa (PA) has historically been one of the major causes of severe sepsis and death among neutropenic cancer patients. There has been a recent increase of multidrug-resistant PA (MDRPA) isolates that may deter…
View article: Urinary infection or radiation cystitis? A prospective evaluation of urinary symptoms in patients submitted to pelvic radiotherapy
Urinary infection or radiation cystitis? A prospective evaluation of urinary symptoms in patients submitted to pelvic radiotherapy Open
OBJECTIVES:The purpose of this study was to evaluate the incidence of urinary tract infection (UTI) in patients with cystitis symptoms who underwent pelvic radiation therapy and identify correlated predictive factors.METHODS:A prospective …
View article: Role of Lock Therapy for Long-Term Catheter-Related Infections by Multidrug-Resistant Bacteria
Role of Lock Therapy for Long-Term Catheter-Related Infections by Multidrug-Resistant Bacteria Open
The management of long-term central venous catheter (LTCVC) infections by multidrug-resistant (MDR) bacteria in cancer patient is a challenge. The objectives of this study were to analyze outcomes in cancer patients with LTCVC-associated i…
View article: Does the Gram-negative Bacteria Colonization Impact on the Risk of Develop Infection by Those Organisms During Neutropenia?
Does the Gram-negative Bacteria Colonization Impact on the Risk of Develop Infection by Those Organisms During Neutropenia? Open
The febrile neutropenia (FN) is a common morbidity among cancer patients and effective initial antimicrobial therapy is associated to low mortality. The aim of this study was to analyze the impact of colonization by multidrug-resistant Gra…
View article: Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma
Genotypic distribution of HHV-8 in AIDS individuals without and with Kaposi sarcoma Open
AIDS-associated Kaposi's sarcoma (AIDS-KS) caused by human herpes virus 8 (HHV-8) is the most severe and resistant form of KS tumor. Our aim was to verify whether there is an association between HHV-8 variability and development of AIDS-KS…