Walid Zaher
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View article: Research Productivity of Health Sciences Institutions in the UAE: 20-Year-Based Bibliometric Analysis
Research Productivity of Health Sciences Institutions in the UAE: 20-Year-Based Bibliometric Analysis Open
The United Arab Emirates (UAE) has undergone a significant transition over the past two decades toward a diversified, knowledge-based economy. These transitions have been driven by governmental policy changes with the vision of placing the…
View article: Psychosocial Needs of Breast Cancer Survivors in the United Arab Emirates (UAE)
Psychosocial Needs of Breast Cancer Survivors in the United Arab Emirates (UAE) Open
Background: Despite the high prevalence of breast cancer, there is limited understanding of the psychosocial needs of cancer survivors in the United Arab Emirates (UAE). Methods: A survey was conducted to assess the psychosocial needs amon…
View article: Clinical Cancer Research in the UAE
Clinical Cancer Research in the UAE Open
The United Arab Emirates (UAE) has cancer as the third leading cause of death. This chapter features clinical research in oncology, focusing on clinical trials in the UAE. Based on the last 10 years of data, the number of cancer-based clin…
View article: Efficacy and Safety of a Booster Vaccination with Two Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: Results of a Double-Blind, Randomized, Placebo-Controlled, Phase 3 Trial in Abu Dhabi
Efficacy and Safety of a Booster Vaccination with Two Inactivated SARS-CoV-2 Vaccines on Symptomatic COVID-19 Infection in Adults: Results of a Double-Blind, Randomized, Placebo-Controlled, Phase 3 Trial in Abu Dhabi Open
Importance: The protective efficacy of COVID-19 vaccinations has declined over time such that booster doses are required. Objective: To evaluate the efficacy and adverse events of booster doses of two inactivated COVID-19 vaccines. Design:…
View article: Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial
Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial Open
An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine candidate, named NVSI-06-09, as a booster dose in subjects aged 18 years and older f…
View article: Diagnostic accuracy of the Cobas 6800 RT-PCR assay for detection of SARS-CoV-2 RNA
Diagnostic accuracy of the Cobas 6800 RT-PCR assay for detection of SARS-CoV-2 RNA Open
Introduction: The COVID-19 pandemic has led to the rapid development and launch of several commercial RT-PCR-based assays for identification of SARS-CoV-2. However, there is need for peer-reviewed evaluation of these assays that can suppor…
View article: Safety and immunogenicity of a broad-spectrum mosaic vaccine as a booster dose against SARS-CoV-2 Omicron and other circulating variants
Safety and immunogenicity of a broad-spectrum mosaic vaccine as a booster dose against SARS-CoV-2 Omicron and other circulating variants Open
BACKGROUND The rising breakthrough infections caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, especially Omicron and its sub-lineages, have raised an urgent need to develop broad-spectrum vaccines against c…
View article: VEGF subtype A and B Gene Expression, Clues to a Temporal Signature in Kawasaki Disease, Implications for Coronary Pathogenesis through a Secondary analysis of Clinical Datasets
VEGF subtype A and B Gene Expression, Clues to a Temporal Signature in Kawasaki Disease, Implications for Coronary Pathogenesis through a Secondary analysis of Clinical Datasets Open
Background and Aim An essential issue for Kawasaki Disease (KD) is the development of coronary artery disease. We decided to investigate (VEGF) subtype gene expression in KD due to the proangiogenic nature of Vasoactive Endothelial Growth …
View article: Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients in a randomized phase 2 trial
Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients in a randomized phase 2 trial Open
NVSI-06-08 is a potential broad-spectrum recombinant COVID-19 vaccine that integrates the antigens from multiple SARS-CoV-2 strains into a single immunogen. Here, we evaluate the safety and immunogenicity of NVSI-06-08 as a heterologous bo…
View article: Vaccine Side Effects Following COVID-19 Vaccination Among the Residents of the UAE—An Observational Study
Vaccine Side Effects Following COVID-19 Vaccination Among the Residents of the UAE—An Observational Study Open
COVID-19 vaccines have proven to be very safe in the clinical trials, however, there is less evidence comparing the safety of these vaccines in real-world settings. Therefore, we aim to investigate the nature and severity of the adverse ef…
View article: Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients: a randomized controlled phase 2 trial
Safety and immunogenicity of a hybrid-type vaccine booster in BBIBP-CorV recipients: a randomized controlled phase 2 trial Open
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants with immune escape ability raises the urgent need for developing cross-neutralizing vaccines against the virus. NVSI-06-08 is a potential broad-spectrum…
View article: Safety and immunogenicity of a heterologous boost with a recombinant vaccine, NVSI-06-07, in the inactivated vaccine recipients from UAE: a phase 2 randomised, double-blinded, controlled clinical trial
Safety and immunogenicity of a heterologous boost with a recombinant vaccine, NVSI-06-07, in the inactivated vaccine recipients from UAE: a phase 2 randomised, double-blinded, controlled clinical trial Open
Summary Background The increased coronavirus disease 2019 (COVID-19) breakthrough cases pose the need of booster vaccinations. In this study, we reported the safety and immunogenicity of a heterologous boost with a recombinant COVID-19 vac…
View article: Response to COVID-19 pandemic in the UAE: A public health perspective
Response to COVID-19 pandemic in the UAE: A public health perspective Open
In the current pandemic of COVID-19 affecting countries across the globe, there are wide variations on how each country is handling the crisis.World leadership, economic status of the country, health care infrastructure, established public…
View article: Evaluation of pooling of samples for testing SARS-COV- 2 for mass screening of COVID-19
Evaluation of pooling of samples for testing SARS-COV- 2 for mass screening of COVID-19 Open
Background The current pandemic of SARS- COV- 2 virus, widely known as COVID-19 has affected millions of people around the world. The World Health Organization (WHO) has recommended vigorous testing to differentiate SARS-CoV-2 from other r…
View article: Clinical prediction system of complications among COVID-19 patients: a development and validation retrospective multicentre study
Clinical prediction system of complications among COVID-19 patients: a development and validation retrospective multicentre study Open
Existing prognostic tools mainly focus on predicting the risk of mortality among patients with coronavirus disease 2019. However, clinical evidence suggests that COVID-19 can result in non-mortal complications that affect patient prognosis…
View article: TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1-p38 Signaling
TAFA2 Induces Skeletal (Stromal) Stem Cell Migration Through Activation of Rac1-p38 Signaling Open
Understanding the mechanisms regulating recruitment of human skeletal (stromal or mesenchymal) stem cells (hMSC) to sites of tissue injury is a prerequisite for their successful use in cell replacement therapy. Chemokine-like protein TAFA2…
View article: CD146/MCAM defines functionality of human bone marrow stromal stem cell populations
CD146/MCAM defines functionality of human bone marrow stromal stem cell populations Open
Background Identification of surface markers for prospective isolation of functionally homogenous populations of human skeletal (stromal, mesenchymal) stem cells (hMSCs) is highly relevant for cell therapy protocols. Thus, we examined the …
View article: Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling
Pharmacological Inhibition of Protein Kinase G1 Enhances Bone Formation by Human Skeletal Stem Cells Through Activation of RhoA-Akt Signaling Open
Development of novel approaches to enhance bone regeneration is needed for efficient treatment of bone defects. Protein kinases play a key role in regulation of intracellular signal transduction pathways, and pharmacological targeting of p…
View article: Additional file 1: of Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells
Additional file 1: of Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells Open
Figure S1. Showing generation and differentiation of hBMSC-TERT-Luc cell lines, Table S1 presenting a list of primers used for RT-PCR, and Table S2 presenting genes upregulated by group 1 (hMSC-TERT+Bone and three HBF clones) over group 2 …