Wei Wu
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Single-Cell Analysis Links C7+ Cancer-Associated Fibroblasts with Incomplete Resection in Platinum-Sensitive Relapsed Ovarian Cancer Open
Background/Objectives: Achieving complete resection (R0) during secondary cytoreduction (SCR) is a pivotal prognostic factor for patients with platinum-sensitive relapsed ovarian cancer (PSROC). Methods: By integrating single-cell RNA sequ…
View article: Landslide detection using multimodal data fusion and an improved Deeplabv3+ model
Landslide detection using multimodal data fusion and an improved Deeplabv3+ model Open
Accurate and efficient detection of landslide hazards is recognized as a critical requirement for both disaster emergency response and long-term land-use planning. However, conventional semantic segmentation models still present notable li…
Comprehensive evaluation and progress of colorectal cancer screening methods Open
The evolution of colorectal cancer (CRC) follows a progression from polyp to adenoma and eventually to cancer. The implementation of CRC screening is an effective strategy to interrupt the disease process and reduce morbidity and mortality…
Xiaozheng Decoction Inhibits Bladder Cancer Progression by Regulating the miR-21/SMAD7 Signaling Axis Open
Background Bladder cancer (BCa) is the most common malignant tumor of the urinary system, and there remains an urgent need for more effective therapeutic strategies. Xiaozheng Decoction has been reported to prevent postoperative recurrence…
Dynamic Nurse Staffing for Better Accompanying Services in Outpatient Departments: Insight from West China Hospital Open
Background: Over the past decade, the demand for accompanying services, which can be provided by both professional nurses and unskilled workers in major general hospitals, escalates significantly. Although nurses can provide higher value a…
View article: Neuropathological comorbidity, genetics and cognition in a Chinese community-based autopsy cohort
Neuropathological comorbidity, genetics and cognition in a Chinese community-based autopsy cohort Open
Neurodegenerative comorbidities are common and critical, yet data specific to the Chinese population remains limited. In this study, we aimed to investigate the prevalence and associations of neuropathological changes and comorbidities and…
A Predictive Model for Acute Kidney Injury Based on Leukocyte‐Related Indicators in Hepatocellular Carcinoma Patients Admitted to the Intensive Care Unit Open
Background: This study aimed to develop and validate a straightforward clinical risk model utilizing white blood cell (WBC) counts to predict acute kidney injury (AKI) in critically sick patients with hepatocellular carcinoma (HCC). Method…
Re-Evaluation and Retrospective Comparison of Serum Neutralization Induced by Three Different Types of Inactivated SARS-CoV-2 Vaccines Open
Background: During the COVID-19 pandemic, three different types of inactivated SARS-CoV-2 vaccines, namely BBIBP-CorV, WIBP-CorV and CoronaVac, were manufactured and used for vaccination in China. However, as far as we know, no comparison …
View article: Nomogram-based prognostic stratification for patients with large hepatocellular carcinoma: a population study of SEER database and a Chinese cohort
Nomogram-based prognostic stratification for patients with large hepatocellular carcinoma: a population study of SEER database and a Chinese cohort Open
Nomogram showed a superior prognostic predictive ability compared with the TNM staging system. The prognostic stratification serves as a valuable tool to assist clinicians on the selection of optimal treatment method and follow-up plan, pa…
The Relationship Between Facilitation of Patient Involvement and Self-Perceived Burden in Postoperative Lung Cancer Patients: The Mediating Role of Social Support Open
The self-perceived burden of patients after lung cancer surgery was at a moderate level, and social support partially mediates the relationship between facilitation of patient involvement and self-perceived burden. Medical staff should enc…
Association between copper intake and essential hypertension: dual evidence from Mendelian randomization analysis and the NHANES database Open
Background Although previous studies have identified an association between trace elements and essential hypertension, the specific trace elements involved and the mechanisms of their association remain unclear. This study aimed to elucida…
Unsupervised Morphological Tree Tokenizer Open
As a cornerstone in language modeling, tokenization involves segmenting text inputs into pre-defined atomic units. Conventional statistical tokenizers often disrupt constituent boundaries within words, thereby corrupting semantic informati…
Bacterial imaging in tumour diagnosis Open
Some bacteria, such as Escherichia coli (E. coli) and Salmonella typhimurium (S. typhimurium), have an inherent ability to locate solid tumours, making them a versatile platform that can be combined with other tools to improve the tumour d…
View article: Correction for: Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy
Correction for: Hyperoside attenuates renal aging and injury induced by D-galactose via inhibiting AMPK-ULK1 signaling-mediated autophagy Open
The authors found that the Western blot image for GAPDH in Figure 4A and the transmission electron micrograph for the D-gal plus vitamin E group in Figure 6C were incorrect due to misuse of data from a different experiment.The authors have…
Self‐Assembled Fe‐Phenolic Acid Network Synergizes with Ferroptosis to Enhance Tumor Nanotherapy Open
Natural polyphenolic compound rosmarinic acid (RA) has good antitumor activity. However, the distinctive tumor microenvironment, characterized by low pH and elevated levels of glutathione (GSH), enhances the tolerance of tumors to the sing…
The QTL and Candidate Genes Regulating the Early Tillering Vigor Traits of Late-Season Rice in Double-Cropping Systems Open
Rice effective panicle is a major trait for grain yield and is affected by both the genetic tiller numbers and the early tillering vigor (ETV) traits to survive environmental adversities. The mechanism behind tiller bud formation has been …
The relationship between self-perceived burden and facilitation of patient involvement in postoperative lung cancer patients: the mediating role of social support Open
Background Lung cancer patients often experience high levels of self-perceived burden, which significantly impacts their quality of life and mental health. Social support is closely associated with self-perceived burden, but the relationsh…
Explore intersection genes of oxymatrine and COVID-19 with lung cancer as potential therapeutic targets based on network pharmacology Open
Introduction. Oxymatrine is a natural quinazine alkaloid extracted from Sophora flavescens and has many medicinal values. Oxymatrine showed protective effects, viral inhibition and effects against lung cancer. Hypothesis/Gap Statement. Ind…
[A Novel Chinese Medicine Formula Inhibits Non-small Cell Lung Cancer by Triggering Oxidative Stress Dependent on Pentose Phosphate Pathway]. Open
NCHF-01 can inhibit NSCLC through oxidative stress dependent on the PPP.
NaYF<sub>4</sub>:Yb/Er@Mn<sub>3</sub>O<sub>4</sub>@GOX Nanocomposite for Upconversion Fluorescence Imaging and Synergistic Cascade Cancer Therapy by Apoptosis and Ferroptosis Open
The cell elimination strategy based on reactive oxygen species (ROS) is a promising method for tumor therapy. However, its efficacy is significantly limited by ROS deficiency caused by H 2 O 2 substrate deficiency and up‐regulation of cell…
Prediction model of clinical prognosis and immunotherapy efficacy of gastric cancer based on level of expression of cuproptosis-related genes Open
Our analysis revealed that the prognostic model of cuproptosis-related genes could effectively predict the prognosis of patients with gastric cancer and comprehensively establish the relationship between cuproptosis genes and tumor immunit…
View article: Inhibition of Tumor Metastasis by Liquid‐Nitrogen‐Shocked Tumor Cells with Oncolytic Viruses Infection (Adv. Mater. 28/2023)
Inhibition of Tumor Metastasis by Liquid‐Nitrogen‐Shocked Tumor Cells with Oncolytic Viruses Infection (Adv. Mater. 28/2023) Open
Drug Delivery In article number 2212210, Funan Liu, Hongjun Li, Zhen Gu, and co-workers present an oncolytic virus therapy that can target metastasis after systemic administration. Tumor cells that have been pre-infected with an oncolytic …