Hechen Wang
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View article: Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128–3p agomir and Oroxin B: A novel drug delivery approach based on PI3K-AKT and VEGF pathway crosstalk
Enhancing HepG2 cell apoptosis with a combined nanoparticle delivery of miR-128–3p agomir and Oroxin B: A novel drug delivery approach based on PI3K-AKT and VEGF pathway crosstalk Open
Hepatocellular carcinoma (HCC) shows the highest morbidity among liver cancers and is a major contributor to cancer-associated mortality. It is characterized by genetic mutations in hepatocytes, leading to uncontrolled cell growth and prol…
View article: Competition Law Response to Platform’s Banning Behavior: Rethinking EU and China’s Solution
Competition Law Response to Platform’s Banning Behavior: Rethinking EU and China’s Solution Open
View article: Site-specific detection of circulating tumor DNA methylation in biological samples utilizing phosphorothioated primer-based loop-mediated isothermal amplification
Site-specific detection of circulating tumor DNA methylation in biological samples utilizing phosphorothioated primer-based loop-mediated isothermal amplification Open
DNA methylation, a kind of epigenetic alteration, plays a vital role in tumorigenesis and offers a new class of targets for cancer treatment. DNA hypermethylation at the E-Box site (CACGTG, -288 bp) in the SLC22A2 promoter was related to m…
View article: Conversation in forums: How software forum posts discuss potential development insights
Conversation in forums: How software forum posts discuss potential development insights Open
User feedback on software usage is utilised by developers to improve their software, and software product forums are platforms rich in software-related user feedback. However, previous studies have mainly focused on analysing forum user fe…
View article: Probing Fast Enantio-Recognition of Drugs with Multiple Chiral Centers by Electrospray-Tandem Mass Spectrometry and Its Mechanism
Probing Fast Enantio-Recognition of Drugs with Multiple Chiral Centers by Electrospray-Tandem Mass Spectrometry and Its Mechanism Open
Chiral drugs are very complex substances since individual enantiomers may differ in pharmacological and toxic effects, making it necessary to analyze enantiomers separately. In this study, we investigated the chiral differentiation of two …
View article: Replication package for "What's Inside a Cluster of Software User Feedback: A Study of Characterisation Methods"
Replication package for "What's Inside a Cluster of Software User Feedback: A Study of Characterisation Methods" Open
Replication package for "What's Inside a Cluster of Software User Feedback: A Study of Characterisation Methods" from Requirements Engineering 2022. Read the README.md file in the root of this zip for more information on how to run the met…
View article: Replication package for "Characterizing Software User Feedback Text Clusters"
Replication package for "Characterizing Software User Feedback Text Clusters" Open
Replication package for "Characterizing Software User Feedback Text Clusters" from Requirements Engineering 2022. Read the README.md file in the root of this zip for more information on how to run the method and evaluation included in the …
View article: Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics
Mechanism Assay of Honeysuckle for Heat-Clearing Based on Metabolites and Metabolomics Open
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as cyclooxygenase (Cox)-1/2 inhibitor, have emerged as potent antipyretics and analgesics. However, few herbs with Cox-1/2 inhibitory activity are commonly used for heat-clearing in China…
View article: Simvastatin inhibits oral squamous cell carcinoma by targeting TMEM16A Ca2+-activated chloride channel
Simvastatin inhibits oral squamous cell carcinoma by targeting TMEM16A Ca2+-activated chloride channel Open
View article: Risk of CAPM Model Apply in Chinese Concept Stocks based on Python
Risk of CAPM Model Apply in Chinese Concept Stocks based on Python Open
View article: Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer
Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer Open
This study aims to investigate the anticancer effect of Oroxin B (OB) both in vitro and in vivo, and the molecular mechanism involved in microRNA-221 and the PI3K/Akt/PTEN pathway through modulation of apoptosis in Hepatocellular carcinoma…
View article: A High-Order Compensated Op-amp-less Bandgap Reference with 39 ppm/ °C over -260~125 °C Temperature Range and -50 dB PSRR
A High-Order Compensated Op-amp-less Bandgap Reference with 39 ppm/ °C over -260~125 °C Temperature Range and -50 dB PSRR Open
This brief presents a technique for compensating the temperature coefficient (TC) of a bandgap reference (BGR) using temperature characteristics of transistor's current gain \b{eta}. As a comparison, three BGR circuits built with Si BJTs a…
View article: A Quadrature VCO with Phase Noise Optimization for Wide Tuning Triple\n Band Frequency Generation
A Quadrature VCO with Phase Noise Optimization for Wide Tuning Triple\n Band Frequency Generation Open
This paper presents an analytical model on quadrature VCO (QVCO) phase noise\nperformance as well as a wide-tuning triple band QVCO RFIC design. The phase\nnoise model demonstrates the advantages of applying phase shift to quadrature\ncoup…
View article: A Quadrature VCO with Phase Noise Optimization for Wide Tuning Triple Band Frequency Generation
A Quadrature VCO with Phase Noise Optimization for Wide Tuning Triple Band Frequency Generation Open
This paper presents an analytical model on quadrature VCO (QVCO) phase noise performance as well as a wide-tuning triple band QVCO RFIC design. The phase noise model demonstrates the advantages of applying phase shift to quadrature couplin…
View article: How robust are color-specific biases in memory?
How robust are color-specific biases in memory? Open
Background: Color matching in both perception and memory is reported to exhibit color-specific patterns of bias and variability that have been accounted for by a model in which color categories influence color selections. (Bae et al, 2015)…