Yuekun Wang
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Author Swipe
View article: Source identification and risk assessment of potentially toxic elements in surface soil of townships in the northwest Hebei region
Source identification and risk assessment of potentially toxic elements in surface soil of townships in the northwest Hebei region Open
Soil environmental quality in townships is related to the development of rural revitalization and the smooth flow of urban-rural integration and development. However, the quality of soil environment in townships may be exposed to potential…
View article: Role of Multiparametric Ultrasound in Predicting the IDH Mutation in Gliomas: Insights from Intraoperative B-Mode, SWE, and SMI Modalities
Role of Multiparametric Ultrasound in Predicting the IDH Mutation in Gliomas: Insights from Intraoperative B-Mode, SWE, and SMI Modalities Open
Objectives: To investigate the correlation between intraoperative conventional ultrasound, SWE, and SMI ultrasound manifestations of glioma and the expression of immunohistochemical markers. Methods: Patients with single superficial suprat…
View article: Application of Assessment Scales in Palliative Care for Glioma: A Systematic Review
Application of Assessment Scales in Palliative Care for Glioma: A Systematic Review Open
BACKGROUND AND OBJECTIVE: Patients with glioma experience a high symptom burden and have diverse palliative care needs. However, the assessment scales used in palliative care remain non-standardized and highly heterogeneous. To eval…
View article: <i>TERT</i><scp>p</scp> Mutation and its Prognostic Value in Glioma Patients Under the 2021 <scp>WHO</scp> Classification: A Real‐World Study
<i>TERT</i><span>p</span> Mutation and its Prognostic Value in Glioma Patients Under the 2021 <span>WHO</span> Classification: A Real‐World Study Open
Background The 2021 WHO Classification of Central Nervous System Tumors introduces more molecular markers for glioma reclassification, including TERT promoter ( TERT p) mutation as a key feature in glioblastoma diagnosis. Aims Given the ch…
View article: Elucidation of the molecular mechanism of type 2 diabetes mellitus affecting the progression of nonalcoholic steatohepatitis using bioinformatics and network pharmacology: A review
Elucidation of the molecular mechanism of type 2 diabetes mellitus affecting the progression of nonalcoholic steatohepatitis using bioinformatics and network pharmacology: A review Open
Increasing evidence suggests that patients with diabetes are at increased risk of developing nonalcoholic steatohepatitis (NASH), but the underlying mechanisms that affect the progression of NASH remain unclear. In this study, we used bioi…
View article: Brain Tumor and Mood Disorders: A Retrospective Analysis of Anxiety and Depression in Patients with Primary and Metastatic Brain Tumors
Brain Tumor and Mood Disorders: A Retrospective Analysis of Anxiety and Depression in Patients with Primary and Metastatic Brain Tumors Open
Brain tumors are associated with a dismal prognosis, and the diagnosis of intracranial tumors can evoke significant psychological disturbance. However, the evolution of patients' emotional status over the clinical course of brain tumors is…
View article: Clinical features, <scp>MRI</scp>, molecular alternations, and prognosis of astrocytoma based on <scp>WHO</scp> 2021 classification of central nervous system tumors: A single‐center retrospective study
Clinical features, <span>MRI</span>, molecular alternations, and prognosis of astrocytoma based on <span>WHO</span> 2021 classification of central nervous system tumors: A single‐center retrospective study Open
Background The diagnosis of glioma has advanced since the release of the WHO 2021 classification with more molecular alterations involved in the integrated diagnostic pathways. Our study aimed to present our experience with the clinical fe…
View article: The molecular signature and prognosis of glioma with preoperative intratumoral hemorrhage: a retrospective cohort analysis
The molecular signature and prognosis of glioma with preoperative intratumoral hemorrhage: a retrospective cohort analysis Open
View article: Clinical application of intraoperative ultrasound superb microvascular imaging in brain tumors resections: contributing to the achievement of total tumoral resection
Clinical application of intraoperative ultrasound superb microvascular imaging in brain tumors resections: contributing to the achievement of total tumoral resection Open
Background To investigate whether the intraoperative superb microvascular imaging(SMI) technique helps evaluate lesion boundaries compared with conventional grayscale ultrasound in brain tumor surgery and to explore factors that may be ass…
View article: A prognostic model for overall survival in recurrent glioma patients treated with bevacizumab-containing therapy
A prognostic model for overall survival in recurrent glioma patients treated with bevacizumab-containing therapy Open
Predictive markers and prognostic models are useful for the individualization of cancer treatment. In this study, we sought to identify clinical and molecular factors to predict overall survival in recurrent glioma patients receiving bevac…
View article: Clinical roles of EGFR amplification in diffuse gliomas: a real-world study using the 2021 WHO classification of CNS tumors
Clinical roles of EGFR amplification in diffuse gliomas: a real-world study using the 2021 WHO classification of CNS tumors Open
Background The 2021 World Health Organization Classification of Central Nervous System Tumors updates glioma subtyping and grading system, and incorporates EGFR amplification (Amp) as one of diagnostic markers for glioblastoma (GBM). Purpo…
View article: Molecular Determinants of Neurocognitive Deficits in Glioma: Based on 2021 WHO Classification
Molecular Determinants of Neurocognitive Deficits in Glioma: Based on 2021 WHO Classification Open
Cognitive impairment is a common feature among patients with diffuse glioma. The objective of the study is to investigate the relationship between preoperative cognitive function and clinical as well as molecular factors, firstly based on …
View article: Ex-Vivo Evaluation of a Novel Miniaturized Epi-Fluorescent Widefield Microscope in Intra-Operative Differentiation between Central Nervous System Lesions and Normal Tissues
Ex-Vivo Evaluation of a Novel Miniaturized Epi-Fluorescent Widefield Microscope in Intra-Operative Differentiation between Central Nervous System Lesions and Normal Tissues Open
View article: Overview and Quantitative Analysis of Glioma Palliative Care Assessment Scales: A Systematic Literature Review
Overview and Quantitative Analysis of Glioma Palliative Care Assessment Scales: A Systematic Literature Review Open
Background: Patients diagnosed with glioma face substantial challenges with poor prognosis, high symptom burden and care needs. The scope of palliative care has also been defined by the WHO (World Health Organization). Palliative care for …
View article: Novel insight into histological and molecular astrocytoma, <scp>IDH</scp>‐mutant, Grade 4 by the updated <scp>WHO</scp> classification of central nervous system tumors
Novel insight into histological and molecular astrocytoma, <span>IDH</span>‐mutant, Grade 4 by the updated <span>WHO</span> classification of central nervous system tumors Open
Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐ mutant, Grade 4. However, the unders…
View article: Researching the molecular mechanisms of Taohong Siwu Decoction in the treatment of varicocele-associated male infertility using network pharmacology and molecular docking: A review
Researching the molecular mechanisms of Taohong Siwu Decoction in the treatment of varicocele-associated male infertility using network pharmacology and molecular docking: A review Open
Taohong Siwu Decoction (THSWD) was widely used for the treatment of varicocele-associated male infertility. However, the pharmacological mechanism of action is not completely clear. Therefore, network pharmacology and molecular docking wer…
View article: Histological and molecular glioblastoma, IDH-wildtype: a real-world landscape using the 2021 WHO classification of central nervous system tumors
Histological and molecular glioblastoma, IDH-wildtype: a real-world landscape using the 2021 WHO classification of central nervous system tumors Open
Introduction Glioblastoma (GBM), the most lethal primary brain malignancy, is divided into histological (hist-GBM) and molecular (mol-GBM) subtypes according to the 2021 World Health Organization classification of central nervous system tu…
View article: Characteristic analysis and identification of novel molecular biomarkers in elderly glioblastoma patients using the 2021 WHO Classification of Central Nervous System Tumors
Characteristic analysis and identification of novel molecular biomarkers in elderly glioblastoma patients using the 2021 WHO Classification of Central Nervous System Tumors Open
Introduction Elderly glioblastoma (GBM) patients is characterized by high incidence and poor prognosis. Currently, however, there is still a lack of adequate molecular characterization of elderly GBM patients. The fifth edition of the WHO …
View article: An online survival predictor in glioma patients using machine learning based on WHO CNS5 data
An online survival predictor in glioma patients using machine learning based on WHO CNS5 data Open
Background The World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas. However, predicting individual patien…
View article: Spotlights on adult patients with pediatric-type diffuse gliomas in accordance with the 2021 WHO classification of CNS tumors
Spotlights on adult patients with pediatric-type diffuse gliomas in accordance with the 2021 WHO classification of CNS tumors Open
Introduction The fifth edition of the World Health Organization (WHO) classification of central nervous system (CNS) tumors released in 2021 formally defines pediatric-type diffuse gliomas. However, there is still little understanding of p…
View article: Recent advances and future challenges of tumor vaccination therapy for recurrent glioblastoma
Recent advances and future challenges of tumor vaccination therapy for recurrent glioblastoma Open
Glioblastoma (GBM) is the most malignant CNS tumor with a highest incidence rate, and most patients would undergo a recurrence. Recurrent GBM (rGBM) shows an increasing resistance to chemotherapy and radiotherapy, leading to a significantl…
View article: Comparative efficacy and rankings of therapeutics for ALK-positive non-small cell lung cancer with brain metastasis: Updated results from a Bayesian network analysis based on randomized controlled trials
Comparative efficacy and rankings of therapeutics for ALK-positive non-small cell lung cancer with brain metastasis: Updated results from a Bayesian network analysis based on randomized controlled trials Open
View article: Molecular determinants of neurocognitive deficits in glioma: based on 2021 WHO classification
Molecular determinants of neurocognitive deficits in glioma: based on 2021 WHO classification Open
Purpose Cognitive impairment is a common feature among patients with diffuse glioma. This study aimed to investigate the relationship between cognitive function and clinical and molecular factors under the new 2021 WHO classification of tu…
View article: Clinical updates on gliomas and implications of the 5th edition of the WHO classification of central nervous system tumors
Clinical updates on gliomas and implications of the 5th edition of the WHO classification of central nervous system tumors Open
Background The 5th edition of the World Health Organization (WHO) classification of central nervous system tumors incorporated specific molecular alterations into the categorization of gliomas. The major revision of the classification sche…
View article: Impact of N,N<a:math xmlns:a="http://www.w3.org/1998/Math/MathML" id="M1"> <a:mo>′</a:mo> </a:math>-Methylene-bis-Morpholine on the Preservation of Natural Rubber Latex
Impact of N,N ′ -Methylene-bis-Morpholine on the Preservation of Natural Rubber Latex Open
Natural rubber latex (NRL) preserved by high ammonia (HA) presents substantial pollution issues despite its good all-around properties. Cleaning preservation of NRL is critical in the modern rubber industry. In this study, NRL was preserve…
View article: Prognostic Prediction Model for Glioblastoma: A Ferroptosis-Related Gene Prediction Model and Independent External Validation
Prognostic Prediction Model for Glioblastoma: A Ferroptosis-Related Gene Prediction Model and Independent External Validation Open
Glioblastoma (GBM) is the most common primary malignant intracranial tumor with a poor prognosis. Ferroptosis is a newly discovered, iron-dependent, regulated cell death, and recent studies suggest its close correlation to GBM. The transcr…
View article: Single-cell transcriptomic analyses provide insights into the cellular origins and drivers of brain metastasis from lung adenocarcinoma
Single-cell transcriptomic analyses provide insights into the cellular origins and drivers of brain metastasis from lung adenocarcinoma Open
Background Brain metastasis (BM) is the most common intracranial malignancy causing significant mortality, and lung cancer is the most common origin of BM. However, the cellular origins and drivers of BM from lung adenocarcinoma (LUAD) hav…
View article: Management of IDH-mutant astrocytoma based on WHO 2021 classification of central nervous system tumors: a single center retrospective study
Management of IDH-mutant astrocytoma based on WHO 2021 classification of central nervous system tumors: a single center retrospective study Open
Purpose: The diagnosis of glioma has got an advance since the WHO 2021 classification published with more molecular alternations involved in the integrate diagnoses pathways. Our study was aimed to show our experience on the clinical featu…
View article: Palliative care for patients with glioma: A recent scientometric analysis of the Web of Science in 2022
Palliative care for patients with glioma: A recent scientometric analysis of the Web of Science in 2022 Open
Background Patients with glioma present with complex palliative care needs throughout their disease trajectory. A scientometric analysis is effective and widely used to summarize the most influential studies within a certain field. We pres…
View article: Prognostic Value of Choline and Other Metabolites Measured Using 1H-Magnetic Resonance Spectroscopy in Gliomas: A Meta-Analysis and Systemic Review
Prognostic Value of Choline and Other Metabolites Measured Using 1H-Magnetic Resonance Spectroscopy in Gliomas: A Meta-Analysis and Systemic Review Open
Glioma is the most prevalent primary central nervous system malignant tumor, with high heterogeneity observed among different grades; therefore, non-invasive prediction of prognosis could improve the clinical management of patients with gl…