Zhiqiang Wang
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View article: Body mass index-dependent therapeutic efficacy in HFmrEF and HFpEF: A systematic review and network meta-analysis
Body mass index-dependent therapeutic efficacy in HFmrEF and HFpEF: A systematic review and network meta-analysis Open
Objectives: Several pharmacological classes have demonstrated favorable impacts on cardiovascular outcomes in patients with heart failure (HF) with preserved ejection fraction (HFpEF) and HF with mildly reduced ejection fraction (HFmrEF). …
View article: Orthogeriatric Co-Management Improves Early Outcomes in Hip Fractures: A Post-Hoc Analysis of a Prospective Study
Orthogeriatric Co-Management Improves Early Outcomes in Hip Fractures: A Post-Hoc Analysis of a Prospective Study Open
Compared with the traditional consultation mode, orthogeriatric co-management care significantly reduced early mortality and enhanced early mobility and quality of life in geriatric hip fracture patients with high ASA score.
View article: Development and primary application of apparatuses for anisotropic soil specimen preparation and suffusion test
Development and primary application of apparatuses for anisotropic soil specimen preparation and suffusion test Open
View article: Research on Land Use in China under the Background of Carbon Emission Based on WOS Database
Research on Land Use in China under the Background of Carbon Emission Based on WOS Database Open
Under the global climate change and the synergistic advancement of the dual-carbon strategy, research on carbon effects of land use and its regulatory pathways has emerged as a core scientific proposition for achieving carbon neutrality. T…
View article: STUDY ON THE ANALYSIS AND APPLICATION OF ETHNIC CULTURAL SYMBOLS IN THE COMMUNICATION OF GUIZHOU "VILLAGE SUPER LEAGUE"
STUDY ON THE ANALYSIS AND APPLICATION OF ETHNIC CULTURAL SYMBOLS IN THE COMMUNICATION OF GUIZHOU "VILLAGE SUPER LEAGUE" Open
This study takes Guizhou’s "Village Super League" (officially named "Guizhou Rongjiang [Sanbao Dong Village] Harmonious and Beautiful Village Football Super League") in China as the research object, systematically exploring the presentatio…
View article: Stress distribution characteristics of overburden strata during thick coal seam top coal caving
Stress distribution characteristics of overburden strata during thick coal seam top coal caving Open
Given the lack of systematic research on the movement of overburden strata and damage characteristics of floor residual coal in the process of thick coal seam top coal caving, this study takes the Anping Coal Mine as the engineering backgr…
View article: Smart Trial: Evaluating the Use of Large Language Models for Recruiting Clinical Trial Participants via Social Media
Smart Trial: Evaluating the Use of Large Language Models for Recruiting Clinical Trial Participants via Social Media Open
Clinical trials (CT) are essential for advancing medical research and treatment, yet efficiently recruiting eligible participants -- each of whom must meet complex eligibility criteria -- remains a significant challenge. Traditional recrui…
View article: Global perspective on the burden of smoking-attributable low back pain: new insights from the global burden of disease study 2021
Global perspective on the burden of smoking-attributable low back pain: new insights from the global burden of disease study 2021 Open
Background This study aimed to examine the evolving trends in the global burden of smoking-attributable low back pain (LBP) from 1990 to 2021 and predicted disease burden until 2035. Methods Using Global Burden of Disease (GBD) 2021 data, …
View article: Predictive Value of Geriatric Nutritional Risk Index for Readmission within 6-Months in Elderly Inpatients with Acute Exacerbation Chronic Obstructive Pulmonary Disease
Predictive Value of Geriatric Nutritional Risk Index for Readmission within 6-Months in Elderly Inpatients with Acute Exacerbation Chronic Obstructive Pulmonary Disease Open
The proportion of nutritional risk was higher in elderly AECOPD inpatients, and GNRI (GNRI ≤ 98) is an independent risk factor for readmission due to acute exacerbations within 6-months.
View article: 693. ESTROUS CYCLE-DEPENDENT EFFECTS OF A TROPOMYOSIN RECEPTOR KINASE B AGONIST ON FEAR EXTINCTION IN FEMALE ADOLESCENT RATS
693. ESTROUS CYCLE-DEPENDENT EFFECTS OF A TROPOMYOSIN RECEPTOR KINASE B AGONIST ON FEAR EXTINCTION IN FEMALE ADOLESCENT RATS Open
Background Fear extinction, a laboratory model for exposure therapy, is modulated by endogenous levels of estradiol in adult female rodents and women, with extinction retention enhanced when extinction training occurs in a high-estradiol p…
View article: Global, regional, and national burden of multiple myeloma, 1990 to 2021 and predictions to 2035: an analysis of the Global Burden of Disease Study 2021
Global, regional, and national burden of multiple myeloma, 1990 to 2021 and predictions to 2035: an analysis of the Global Burden of Disease Study 2021 Open
Background and objective Multiple myeloma (MM) is the second most common haematologic malignancy. This study aimed to assess the global burden of multiple myeloma across 204 countries and territories from 1990 to 2021. Methods The data for…
View article: Experimental study of intravoxel incoherent motion diffusion imaging combined with ultrasound renal resistance index in contrast-induced nephropathy
Experimental study of intravoxel incoherent motion diffusion imaging combined with ultrasound renal resistance index in contrast-induced nephropathy Open
The synergistic application of IVIM and RRI techniques offers a non-invasive approach for early detection of renal damage after ioversol exposure and is a potent method for observing the pathophysiological shifts associated with early-stag…
View article: Biomechanical evaluation of In-Out-In pedicle screws for atlantoaxial posterior fixation in the presence of high-riding vertebral artery and narrow C2 pedicles: a finite element analysis
Biomechanical evaluation of In-Out-In pedicle screws for atlantoaxial posterior fixation in the presence of high-riding vertebral artery and narrow C2 pedicles: a finite element analysis Open
Introduction In patients with high-riding vertebral artery (HRVA) and narrow pedicles, placement of C2 pedicle screws carries a significant risk of vertebral artery injury. The in-out-in pedicle screws (IOIPS) technique offers an alternati…
View article: Osteoporosis in adjacent cervical segments exacerbates disc herniation
Osteoporosis in adjacent cervical segments exacerbates disc herniation Open
View article: Visualization and manipulation of four-leaf clover-shaped electronic state in cuprate
Visualization and manipulation of four-leaf clover-shaped electronic state in cuprate Open
High-Tc superconductivity in cuprates arises from carrier doping of an antiferromagnetic Mott insulator. Associated with these changes are spectral-weight transfers from the high-energy to low-energy, giving rise to a variety of intriguing…
View article: Microbiota-derived butyrate alleviates asthma via inhibiting Tfh13-mediated IgE production
Microbiota-derived butyrate alleviates asthma via inhibiting Tfh13-mediated IgE production Open
Gut microbiota-derived short-chain fatty acids (SCFAs) impact asthma outcomes, highlighting the importance of understanding the disease mechanisms through the gut–lung axis. In this study, we identified that among SCFAs, butyrate uniquely …
View article: Mechanisms and Factors Influencing Resorption of Herniated Part of Lumbar Disc Herniation: Comprehensive Review
Mechanisms and Factors Influencing Resorption of Herniated Part of Lumbar Disc Herniation: Comprehensive Review Open
Literature was systematically searched in PubMed, Web of Science, and CNKI (2000-2024) using keywords: 'lumbar disc herniation,' 'resorption,' 'autophagy,' 'TCM.' Inclusion criteria: (1) human/animal studies; (2) MRI-confirmed LDH; (3) Eng…
View article: OP0302 RUZINURAD FOR HYPERURICEMIA ASSOCIATED WITH PRIMARY GOUT: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, ACTIVE-CONTROLLED, PHASE 3 STUDY
OP0302 RUZINURAD FOR HYPERURICEMIA ASSOCIATED WITH PRIMARY GOUT: A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, ACTIVE-CONTROLLED, PHASE 3 STUDY Open
View article: Experimental Study of Intravoxel Incoherent Motion Diffusion Imaging Combined with Ultrasound Renal Resistance Index in Contrast-Induced Nephropathy
Experimental Study of Intravoxel Incoherent Motion Diffusion Imaging Combined with Ultrasound Renal Resistance Index in Contrast-Induced Nephropathy Open
Objective This study explored the application of Intravoxel Incoherent Motion (IVIM) diffusion imaging combined with Ultrasound Renal Resistance Index (RRI) for monitoring the pathophysiological changes associated with early contrast-induc…
View article: Cdkl5 Knockout Mice Recapitulate Sleep Phenotypes of CDKL5 Deficient Disorder
Cdkl5 Knockout Mice Recapitulate Sleep Phenotypes of CDKL5 Deficient Disorder Open
Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is an X-linked rare neurodevelopmental disorder associated with severe sleep disturbances. However, little is known about the mechanisms underlying sleep disturbances in CDD …
View article: Inducing mononuclear cells of patients with CADASIL to construct a CSVD disease model
Inducing mononuclear cells of patients with CADASIL to construct a CSVD disease model Open
Reprogramming technology can be used to induce PBMCs to become iPSCs, and a CSVD disease model can be successfully constructed by culturing and differentiating the iPSCs into CADASIL vascular organoids. The NOTCH3 p.R141C mutation suppress…
View article: Restoration of Transgelin 2 Expression Reverses Immune Escape in Ovarian Cancer: A Dawn for Immunotherapy
Restoration of Transgelin 2 Expression Reverses Immune Escape in Ovarian Cancer: A Dawn for Immunotherapy Open
View article: A Comparison of 3 Minimally Invasive Surgeries for Treating Axillary Osmidrosis
A Comparison of 3 Minimally Invasive Surgeries for Treating Axillary Osmidrosis Open
Background Axillary osmidrosis is a common cause of physical and social discomfort. Although many treatments are available, there is still room for improvement. Objective For treatments of axillary osmidrosis 3 minimally invasive surgical …
View article: Multifocal cancer is associated with better survival than solitary cancer in non-Hispanic White patients with thyroid carcinoma
Multifocal cancer is associated with better survival than solitary cancer in non-Hispanic White patients with thyroid carcinoma Open
Multifocal thyroid carcinoma is associated with better CSS and OS than solitary cancer in NHW patients.
View article: Evaluation of the effect of cervical spine bone distribution on fixation in ankylosing spondylitis
Evaluation of the effect of cervical spine bone distribution on fixation in ankylosing spondylitis Open
Purpose The distribution of cervical bones in ankylosing spondylitis (AS) differs from that of the normal cervical spine. Traditional simulation methods often yield inaccurate results in finite element analysis. The current study aimed to …
View article: Correction: MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer
Correction: MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer Open
View article: Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer
Circular RNA circBNC2 inhibits tumorigenesis by modulating ferroptosis and acts as a nanotherapeutic target in prostate cancer Open
View article: MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer
MORF4L2 induces immunosuppressive microenvironment and immunotherapy resistance through GRHL2/MORF4L2/H4K12Ac/CSF1 axis in triple-negative breast cancer Open
Background Although immunotherapy has achieved great progress in advanced triple-negative breast cancer (TNBC), there are still numerous patients who do not benefit from immunotherapy. Therefore, identification of the key molecule that ind…
View article: Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021
Analysis and comparison of the trends in burden of spinal cord injury in China and worldwide from 1990 to 2021: an analysis of the global burden of disease study 2021 Open
Background Spinal cord injury (SCI) is a globally prevalent neurological condition, often resulting in motor, sensory, and autonomic dysfunctions that lead to permanent disability. However, outdated epidemiological data hinder the developm…
View article: Causal Relationships Between 4 Exposure Factors and Rotator Cuff Syndrome Using Mendelian Randomization Analysis
Causal Relationships Between 4 Exposure Factors and Rotator Cuff Syndrome Using Mendelian Randomization Analysis Open
Background: Although previous studies have investigated the risk factors for rotator cuff syndrome (RCS), there remains controversy due to uncontrolled and uncertain confounding factors in their analyses. Purpose: To perform Mendelian rand…