Wangdong Zhang
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View article: Isolation, identification and characteristics of Aeromonas sobria from diseased rainbow trout (Oncorhynchus mykiss)
Isolation, identification and characteristics of Aeromonas sobria from diseased rainbow trout (Oncorhynchus mykiss) Open
Aeromonas sobria is an opportunistic pathogen that can infect humans, animals and aquatic species, which is widely distributed in different aquatic environments and products. In recent years, with the rapid expansion of intensive aquacultu…
View article: Regionalization of intestinal microbiota and metabolites in the small intestine of the Bactrian camel
Regionalization of intestinal microbiota and metabolites in the small intestine of the Bactrian camel Open
Introduction Peyer's patches (PPs) are crucial antigen-inductive sites of intestinal mucosal immunity. Prior research indicated that, in contrast to other ruminants, PPs in the small intestine of Bactrian camels are found in the duodenum, …
View article: Effect of oregano essential oil on intestinal immunoglobulin G in Holstein dairy bulls
Effect of oregano essential oil on intestinal immunoglobulin G in Holstein dairy bulls Open
Introduction Immunoglobulin G (IgG) is important in mediating humoral immunity and in the maintenance of immune homeostasis in the intestinal mucosa. Oregano essential oil (OEO) is a natural herbal extract that possesses antimicrobial, ant…
View article: Moniezia benedeni drives the SNAP-25 expression of the enteric nerves in sheep's small intestine
Moniezia benedeni drives the SNAP-25 expression of the enteric nerves in sheep's small intestine Open
Background The neuroimmune network plays a crucial role in regulating mucosal immune homeostasis within the digestive tract. Synaptosome-associated protein 25 (SNAP-25) is a presynaptic membrane-binding protein that activates ILC2s, initia…
View article: The addition of Allium mongolicum Regel powder does not appear to affect Firmicutes or Bacteroidota as core microbes in the Angus calf fecal microbiome
The addition of Allium mongolicum Regel powder does not appear to affect Firmicutes or Bacteroidota as core microbes in the Angus calf fecal microbiome Open
Increasing apparent nutrient digestibility is critical for improving beef cattle growth performance and increasing ranch profitability. Therefore, we investigated the effects of the dynamic assembly process of Allium mongolicum Regel powde…
View article: Distribution characteristics of gastric mucosal colonizing microorganisms in different glandular regions of Bactrian camels and their relationship with local mucosal immunity
Distribution characteristics of gastric mucosal colonizing microorganisms in different glandular regions of Bactrian camels and their relationship with local mucosal immunity Open
Bactrian camels inhabiting desert and semi-desert regions of China are valuable animal models for studying adaptation to desert environments and heat stress. In this study, 16S rRNA technology was employed to investigate the distribution c…
View article: Moniezia benedeni drives CD3+ T cells residence in the sheep intestinal mucosal effector sites
Moniezia benedeni drives CD3+ T cells residence in the sheep intestinal mucosal effector sites Open
Introduction T cells are the core of the cellular immunity and play a key role in the regulation of intestinal immune homeostasis. In order to explore the impact Moniezia benedeni ( M. benedeni ) infection on distributions of CD3 + T cells…
View article: Effects of Oregano Essential Oil on IgA+, IgG+, and IgM+ Cells in the Jejunum of Castrated Holstein Bulls
Effects of Oregano Essential Oil on IgA+, IgG+, and IgM+ Cells in the Jejunum of Castrated Holstein Bulls Open
The aim of this study was to investigate the effect of oregano essential oil on IgA+, IgG+, and IgM+ cells in the jejunum of castrated Holstein bulls. Twelve castrated Holstein bulls were randomly divided into control (YCK) and oregano ess…
View article: The Distribution Characteristics of IgA and IgG Antibody-Secreting Cells in the Pharyngeal Tonsils of Bactrian Camels of Different Ages
The Distribution Characteristics of IgA and IgG Antibody-Secreting Cells in the Pharyngeal Tonsils of Bactrian Camels of Different Ages Open
Background: The pharyngeal tonsils, located in the nasopharynx, can effectively defend against invading pathogens of the upper respiratory tract, and play an important role in mucosal immunity of the respiratory tract. IgA and IgG are two …
View article: Yujin powder improves large intestine dampness‐heat syndrome by regulating gut microbiota and serum metabolism
Yujin powder improves large intestine dampness‐heat syndrome by regulating gut microbiota and serum metabolism Open
Large intestine dampness‐heat syndrome (LIDHS) is a common syndrome type in animal diarrheal diseases. Yujin powder (YJP) is one of the classic prescriptions for treating damp‐heat diarrhea. The aim of this study was to investigate the reg…
View article: Proteomic analysis reveals similarity of expression profile in aggregated lymphoid nodules in the abomasum with Peyer’s patches of Bactrian camel
Proteomic analysis reveals similarity of expression profile in aggregated lymphoid nodules in the abomasum with Peyer’s patches of Bactrian camel Open
Background Aggregated lymphoid nodules area (ALNA) is a distinctive anatomical feature of the abomasum in Bactrian camels, consisting of the reticular mucosal folds region (RMFR) and the longitudinal mucosal folds region (LMFR). ALNA exhib…
View article: Localization of FGF21 Protein and Lipid Metabolism-Related Genes in Camels
Localization of FGF21 Protein and Lipid Metabolism-Related Genes in Camels Open
With the ability to survive under drought and chronic hunger, camels display a unique regulation characteristic of lipid metabolism. Fibroblast growth factor (FGF) 21 is a peptide hormone that regulates metabolic pathways, especially lipid…
View article: Establishment of Bactrian Camel Induced Pluripotent Stem Cells and Prediction of Their Unique Pluripotency Genes
Establishment of Bactrian Camel Induced Pluripotent Stem Cells and Prediction of Their Unique Pluripotency Genes Open
Induced pluripotent stem cells (iPSCs) can differentiate into all types of cells and can be used in livestock for research on biological development, genetic breeding, and in vitro genetic resource conservation. The Bactrian camel is a lar…
View article: Peer Review #1 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.2)"
Peer Review #1 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.2)" Open
Bactrian camels have specific mucosa-associated lymphoid tissue (MALT) throughout the large intestine, with species-unique cystic Peyer's patches (PPS) as the main type of tissue.However, detailed information about the molecular characteri…
View article: Peer Review #1 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.1)"
Peer Review #1 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.1)" Open
Bactrian camels have specific mucosa-associated lymphoid tissue (MALT) throughout the large intestine, with species-unique cystic Peyer's patches (PPS) as the main type of tissue.However, detailed information about the molecular characteri…
View article: Peer Review #3 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.1)"
Peer Review #3 of "Integrated omics analysis reveals the immunologic characteristics of cystic Peyer’s patches in the cecum of Bactrian camels (v0.1)" Open
Bactrian camels have specific mucosa-associated lymphoid tissue (MALT) throughout the large intestine, with species-unique cystic Peyer's patches (PPS) as the main type of tissue.However, detailed information about the molecular characteri…
View article: Additional file 1 of Similar proteome expression profiles of the aggregated lymphoid nodules area and Peyer’s patches in Bactrian camel
Additional file 1 of Similar proteome expression profiles of the aggregated lymphoid nodules area and Peyer’s patches in Bactrian camel Open
Supplementary Material 1
View article: Moniezia benedeni Infection Restrain IgA+, IgG+, and IgM+ Cells Residence in Sheep (Ovis aries) Small Intestine
Moniezia benedeni Infection Restrain IgA+, IgG+, and IgM+ Cells Residence in Sheep (Ovis aries) Small Intestine Open
Secreted immunoglobulin A (SIgA), IgG, and IgM play a crucial role in forming the intestinal mucosal immune barrier, and parasites could disturb the host's immune response by releasing various immunomodulatory molecules. Moniezia benedeni …
View article: Moniezia benedeni infection enhances neuromedin U (NMU) expression in sheep (Ovis aries) small intestine
Moniezia benedeni infection enhances neuromedin U (NMU) expression in sheep (Ovis aries) small intestine Open
Background Neuromedin U (NMU) plays an important role in activating the group 2 innate lymphoid cells (ILC2s) and initiating the host’s anti-parasitic immune responses. It is aimed to explore the distribution characteristics of NMU in the …
View article: Expression characteristics of polymeric immunoglobulin receptor in Bactrian camel (Camelus bactrianus) lungs
Expression characteristics of polymeric immunoglobulin receptor in Bactrian camel (Camelus bactrianus) lungs Open
Polymeric immunoglobulin receptor (pIgR), the transmembrane transporter of polymeric immunoglobulin A and M, has multiple immune functions. To explore the characteristics of pIgR expression in Bactrian camel lungs, twelve healthy adult (2–…
View article: Semi-Covariance Coefficient Analysis of Spike Proteins from SARS-CoV-2 and other Coronaviruses for Viral Evolution and Characteristics Associated with Fatality
Semi-Covariance Coefficient Analysis of Spike Proteins from SARS-CoV-2 and other Coronaviruses for Viral Evolution and Characteristics Associated with Fatality Open
Complex modeling has received significant attention in recent years and is increasingly used to explain the statistical phenomenon with increasing and decreasing fluctuations such as the similarity or difference of spike protein charge pat…
View article: Bacterial community analysis on the different mucosal immune inductive sites of gastrointestinal tract in Bactrian camels
Bacterial community analysis on the different mucosal immune inductive sites of gastrointestinal tract in Bactrian camels Open
The microbial communities colonize the mucosal immune inductive sites could be captured by hosts, which could initiate the mucosal immune responses. The aggregated lymphoid nodule area (ALNA) and the ileal Payer's patches (PPs) in Bactrian…
View article: The distributive and structural characteristics of bronchus-associated lymphoid tissue (BALT) in Bactrian camels (<i>Camelus bactrianus</i>)
The distributive and structural characteristics of bronchus-associated lymphoid tissue (BALT) in Bactrian camels (<i>Camelus bactrianus</i>) Open
Background Bronchus-associated lymphoid tissue (BALT), distributed in the bronchial mucosa, plays a critical role in maintaining the mucosal immune homeostasis of the lower respiratory tract. The bronchial tree is a functional structure fo…
View article: The Distribution of SIgA and IgG Antibody-Secreting Cells in the Small Intestine of Bactrian Camels (Camelus bactrianus) of Different Ages
The Distribution of SIgA and IgG Antibody-Secreting Cells in the Small Intestine of Bactrian Camels (Camelus bactrianus) of Different Ages Open
Secretory immunoglobulin A (SIgA) and immunoglobulin G (IgG) antibody-secreting cells (ASCs) are two important cell types in the mucosal immune system. This study aimed to explore the distribution of these ASC populations in the small inte…