Wanqin Zhang
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View article: Fucoidan Improves Tumour Control and Liver Function in <scp>TACE</scp> for Unresectable Hepatocellular Carcinoma: A Randomised Trial
Fucoidan Improves Tumour Control and Liver Function in <span>TACE</span> for Unresectable Hepatocellular Carcinoma: A Randomised Trial Open
Background Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related mortality. Transarterial chemoembolization (TACE) is the standard locoregional therapy for unresectable HCC but is limited by high recurrence and hepatic toxici…
View article: The Construction and Performance Evaluation of a Risk Prediction Model for Nonalcoholic Steatohepatitis Based on Serological Markers
The Construction and Performance Evaluation of a Risk Prediction Model for Nonalcoholic Steatohepatitis Based on Serological Markers Open
Background and Aims To develop a noninvasive clinical diagnostic model based on serological markers for nonalcoholic steatohepatitis (NASH) and to verify its predictive efficacy. Methods A total of 82 biopsy‐proven patients with nonalcohol…
View article: Structural Insights into the Dynamic Assembly of a YFV sNS1 Tetramer
Structural Insights into the Dynamic Assembly of a YFV sNS1 Tetramer Open
Yellow fever virus (YFV) infections can cause severe diseases in humans, resulting in mass casualties in Africa and the Americas each year. Secretory NS1 (sNS1) is thought to be used as a diagnostic marker of flavivirus infections, playing…
View article: Impact of Long-Term Bottle Aging on Color Transition, Polymers, and Aromatic Compounds in Mulberry Wine
Impact of Long-Term Bottle Aging on Color Transition, Polymers, and Aromatic Compounds in Mulberry Wine Open
Long-term aging has traditionally been associated with issues such as color fading and oxidation; therefore, it limits grape wine production. Here, we analyzed 90 bottles of mulberry wine aged for various periods (up to 12 years) and obser…
View article: Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1
Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1 Open
Antibodies targeting non-structural protein 1 (NS1) confer protection against Zika virus (ZIKV). Although monoclonal antibodies (MAbs) 3G2 and 4B8 are more potent than MAb 4F10 in suppressing ZIKV infection in neonatal mice models, the epi…
View article: The step-by-step assembly mechanism of secreted flavivirus NS1 tetramer and hexamer captured at atomic resolution
The step-by-step assembly mechanism of secreted flavivirus NS1 tetramer and hexamer captured at atomic resolution Open
Flaviviruses encode a conserved, membrane-associated nonstructural protein 1 (NS1) with replication and immune evasion functions. The current knowledge of secreted NS1 (sNS1) oligomers is based on several low-resolution structures, thus hi…
View article: A High-Performance Food Package Material Prepared by the Synergistic Crosslinking of Gelatin with Polyphenol–Titanium Complexes
A High-Performance Food Package Material Prepared by the Synergistic Crosslinking of Gelatin with Polyphenol–Titanium Complexes Open
This study aims to enhance gelatin film performance in the food industry by incorporating polyphenol–titanium complexes (PTCs) as crosslinkers. PTCs introduce multiple linkages with gelatin, including coordination and hydrogen bonds, resul…
View article: Microbial composition play the leading role in volatile fatty acid production in the fermentation of different scale of corn stover with rumen fluid
Microbial composition play the leading role in volatile fatty acid production in the fermentation of different scale of corn stover with rumen fluid Open
Rumen fluid is a natural and green biocatalyst that can efficiently degrade biomass into volatile fatty acid (VFA) used to produce value-added materials. But the essence of high degradation efficiency in the rumen has not been fully analyz…
View article: Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1
Structural insights into the distinct protective mechanisms of human antibodies targeting ZIKV NS1 Open
Zika virus (ZIKV) Non-structural protein 1 (NS1) plays an essential role in viral replication and immune evasion. Our understanding of the differential protective mechanism of NS1-targeting antibodies is limited. Here, we determined the cr…
View article: Polyhydroxyalkanoates production from lactic acid fermentation broth of agricultural waste without extra purification: The effect of concentrations
Polyhydroxyalkanoates production from lactic acid fermentation broth of agricultural waste without extra purification: The effect of concentrations Open
Polyhydroxyalkanoates (PHAs) production can potentially realize the high-value utilization of agricultural wastes and reduce the cost of commercial PHA production. This study aimed to explore the feasibility of converting lactic acid (LA) …
View article: Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium
Global disparities in mortality and liver transplantation in hospitalised patients with cirrhosis: a prospective cohort study for the CLEARED Consortium Open
View article: Comparative contribution of substrate structure and microbial composition to volatile fatty acid production in the fermentation of corn stover
Comparative contribution of substrate structure and microbial composition to volatile fatty acid production in the fermentation of corn stover Open
Rumen fluid is anatural and green catalyst that can efficiently degrade biomass into volatile fatty acid (VFA) which can be used toproducevalue-addedmaterials. But the essence of high degradation efficiency in the rumen has not been fully …
View article: Construction of PAN-based activated carbon nanofibers for hydrogen storage under ambient pressure
Construction of PAN-based activated carbon nanofibers for hydrogen storage under ambient pressure Open
Adsorption agents are an important class of solid hydrogen storage materials. Attributed to their high specific surface area and adjustable nanopore structure, activated carbon nanofibers have attracted extensive attention in the applicati…
View article: Efficient Production of Lactic Acid from Anaerobic Co-Fermentation of Starch and Nitrogen-Rich Agro-Industrial Waste Using a Batch System
Efficient Production of Lactic Acid from Anaerobic Co-Fermentation of Starch and Nitrogen-Rich Agro-Industrial Waste Using a Batch System Open
View article: Antibiotic and Antibiotic Resistance Gene Removal Potential for Anaerobic Digestion (Ad) Producing Lactic Acid (La)
Antibiotic and Antibiotic Resistance Gene Removal Potential for Anaerobic Digestion (Ad) Producing Lactic Acid (La) Open
View article: Alterations in gut microbiome and metabolomics in chronic hepatitis B infection-associated liver disease and their impact on peripheral immune response
Alterations in gut microbiome and metabolomics in chronic hepatitis B infection-associated liver disease and their impact on peripheral immune response Open
Gut dysbiosis has been reported in chronic hepatitis B (CHB) infection, however its role in CHB progression and antiviral treatment remains to be clarified. Herein, the present study aimed to characterize gut microbiota (GM) in patients wi…
View article: The chemical components, action mechanisms, and clinical evidences of YiQiFuMai injection in the treatment of heart failure
The chemical components, action mechanisms, and clinical evidences of YiQiFuMai injection in the treatment of heart failure Open
YiQiFuMai injection (YQFM), derived from Shengmai Powder, is wildly applied in the treatment of cardiovascular diseases, such as coronary heart disease and chronic cardiac insufficiency. YiQiFuMai injection is mainly composed of Radix of P…
View article: Direct Purification of Digestate Using Polymeric Ultrafiltration Membranes: Influence of Materials on Filtration Behavior and Fouling Characteristics
Direct Purification of Digestate Using Polymeric Ultrafiltration Membranes: Influence of Materials on Filtration Behavior and Fouling Characteristics Open
In-depth exploration of filtration behavior and fouling characteristics of polymeric ultrafiltration (UF) membranes can provide guidance for the selection of materials and the control of membrane fouling during the purification of digestat…
View article: Discovery and significance of nanoparticles released by plants
Discovery and significance of nanoparticles released by plants Open
As an important part of nature, the role of plants in the material cycle has been widely studied. Nanoparticles, as a common form of existence, have also been confirmed to be absorbed and retained by plants, but there are few studies on th…
View article: QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy
QiShenYiQi pill for myocardial collagen metabolism and apoptosis in rats of autoimmune cardiomyopathy Open
The QSYQ can improve myocardial collagen metabolism by inhibiting apoptosis, which provides a potential therapeutic approach for autoimmune cardiomyopathy.
View article: A Short-circuit Model Based on Artificial Neural Network and Artificial Bee Colony Algorithm for SiC MOSFETs
A Short-circuit Model Based on Artificial Neural Network and Artificial Bee Colony Algorithm for SiC MOSFETs Open
A short-circuit model for silicon carbide (SiC) metal-oxide semiconductor field effect transistors (MOSFETs) using hybrid modeling method based on artificial neural network (ANN) and improved artificial bee colony (ABC) algorithm is propos…
View article: Medium-Chain Carboxylates Production from Co-Fermentation of Swine Manure and Maize Silage Via Lactic Acid: Without External Electron Donors
Medium-Chain Carboxylates Production from Co-Fermentation of Swine Manure and Maize Silage Via Lactic Acid: Without External Electron Donors Open
View article: Improving Production of Lactic Acid and Volatile Fatty Acids from Dairy Cattle Manure and Corn Straw Silage: Effects of Mixing Ratios and Temperature
Improving Production of Lactic Acid and Volatile Fatty Acids from Dairy Cattle Manure and Corn Straw Silage: Effects of Mixing Ratios and Temperature Open
View article: DC model for SiC MOSFETs using artificial neural network optimized by artificial bee colony algorithm
DC model for SiC MOSFETs using artificial neural network optimized by artificial bee colony algorithm Open
A DC model for silicon carbide (SiC) metal–oxide–semiconductor field effect transistors (MOSFETs) is proposed in this paper using a hybrid modeling method based on the artificial neural network and artificial bee colony (ABC) algorithm. A …
View article: Shenmai Injection Alleviates Cardiomyocyte Apoptosis Induced by Doxorubicin
Shenmai Injection Alleviates Cardiomyocyte Apoptosis Induced by Doxorubicin Open
Background: Shenmai Injection (SMI) is a patented Chinese medicine extract, has been widely used to treat myocardial damage caused by doxorubicin (DOX), but its underlying mechanisms remain elusive. The study aimed to explore the protectiv…
View article: Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1
Shenmai injection improves doxorubicin cardiotoxicity via miR-30a/Beclin 1 Open
View article: The emerging role of circular RNAs in cardiovascular diseases
The emerging role of circular RNAs in cardiovascular diseases Open
Cardiovascular disease (CVD) is one of the vital causes of morbidity and mortality, and the number of deaths from CVD has increased worldwide. Circular RNAs (circRNAs) is a novel type of endogenous noncoding RNA, which can form covalent cl…
View article: Roles of Micro-Aeration on Enhancing Volatile Fatty Acids and Lactic Acid Production from Swine Manure and Corn Silage
Roles of Micro-Aeration on Enhancing Volatile Fatty Acids and Lactic Acid Production from Swine Manure and Corn Silage Open
View article: Interaction between Swine Manure Containing Sulfachloropyridazine (SCP) and Anaerobic Digestion (AD) Process for Volatile Fatty Acids (VFAs): SCP Reduction, VFAs Production and Microbial Communities
Interaction between Swine Manure Containing Sulfachloropyridazine (SCP) and Anaerobic Digestion (AD) Process for Volatile Fatty Acids (VFAs): SCP Reduction, VFAs Production and Microbial Communities Open
View article: Fast autaptic feedback induced-paradoxical changes of mixed-mode bursting and bifurcation mechanism
Fast autaptic feedback induced-paradoxical changes of mixed-mode bursting and bifurcation mechanism Open
Bursting is a complex multiple-time-scale nonlinear phenomenon in a nervous system and exhibits diverse patterns, which is modulated by the excitatory or inhibitory effect to achieve the physiological functions. According to the bifurcatio…