Wanqing Liu
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View article: Camera traps reveal grouping behaviour and spatio-temporal partitioning patterns of East China sika deer ( <i>Cervus nippon kopschi</i> )
Camera traps reveal grouping behaviour and spatio-temporal partitioning patterns of East China sika deer ( <i>Cervus nippon kopschi</i> ) Open
Animal behaviour is the overall response to changes in both external environment and internal physiological processes, and investigating the behavioural rhythms of wildlife is essential for understanding the spatio-temporal dynamics of the…
View article: Sex-based multiomics analysis uncovers metabolic and molecular mediators linking MASH and atherosclerosis
Sex-based multiomics analysis uncovers metabolic and molecular mediators linking MASH and atherosclerosis Open
View article: Bile Acid Analogs with Anti-Germination Activities for Prophylaxis of Clostridioides difficile Infection Alter Bile Acid Homeostasis in the Enterohepatic Cycle
Bile Acid Analogs with Anti-Germination Activities for Prophylaxis of Clostridioides difficile Infection Alter Bile Acid Homeostasis in the Enterohepatic Cycle Open
We previously reported that two bile acid (BA) analogs, CamSA and CA-Quin, demonstrate potent anti-germination activity against Clostridioides difficile (C. difficile) spores, protecting rodents from C. difficile infections. Here, we furth…
View article: Wafer-scale uniform epitaxy of transferable 2D single crystals for gate-all-around nanosheet field effect transistors
Wafer-scale uniform epitaxy of transferable 2D single crystals for gate-all-around nanosheet field effect transistors Open
Gate-all-around (GAA) nanosheet field-effect transistors (FETs) with two-dimensional (2D) semiconductor channels surrounded by high-κ dielectrics show outstanding performance and hold promise for ultimate miniaturization in the post-Moore …
View article: Genomic Surveillance for SARS-CoV-2 During the COVID-19 Pandemic: Collaborative Experience at Southeast Michigan
Genomic Surveillance for SARS-CoV-2 During the COVID-19 Pandemic: Collaborative Experience at Southeast Michigan Open
Regional genomic surveillance is essential for tracking viral evolution and informing targeted public health responses. During the COVID-19 pandemic, we established a collaborative genomic surveillance pipeline for SARS-CoV-2 in Southeast …
View article: Bile Acid Analogs with Anti-Germination Activities for Prophylaxis of <em>Clostridioides difficile</em> Infection Alter Bile Acid Homeostasis in the Enterohepatic Cycle
Bile Acid Analogs with Anti-Germination Activities for Prophylaxis of <em>Clostridioides difficile</em> Infection Alter Bile Acid Homeostasis in the Enterohepatic Cycle Open
We previously reported that two bile acid (BA) analogs CamSA and CA-Quin demonstrate potent anti-germination activity against Clostridioides difficile (C. difficile) spores, protecting rodents from C. difficile infections. Here we further …
View article: Machine learning-based prediction of adverse pregnancy outcomes in antiphospholipid syndrome using pregnancy antibody levels
Machine learning-based prediction of adverse pregnancy outcomes in antiphospholipid syndrome using pregnancy antibody levels Open
Background Antiphospholipid syndrome (APS) is a major immune-related disorder that leads to adverse pregnancy outcomes (APO), including recurrent miscarriage, placental abruption, preterm birth, and fetal growth restriction. Antiphospholip…
View article: 764 | REAL‐WORLD OUTCOMES OF MITOXANTRONE HYDROCHLORIDE LIPOSOME REGIMEN FOR PERIPHERAL T‐CELL LYMPHOMA: THE EFFICACY AND SAFETY ANALYSIS OF TREATMENT‐NAÏVE POPULATION
764 | REAL‐WORLD OUTCOMES OF MITOXANTRONE HYDROCHLORIDE LIPOSOME REGIMEN FOR PERIPHERAL T‐CELL LYMPHOMA: THE EFFICACY AND SAFETY ANALYSIS OF TREATMENT‐NAÏVE POPULATION Open
View article: 547 | A PROSPECTIVE MULTICENTER STUDY OF FCR ALTERNATING WITH IBRUTINIB IN TREATMENT‐NAIVE PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA
547 | A PROSPECTIVE MULTICENTER STUDY OF FCR ALTERNATING WITH IBRUTINIB IN TREATMENT‐NAIVE PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA Open
View article: The Patatin-Like Phospholipase Domain–Containing 3 148M Variant Exacerbates Alcohol-Induced Liver Injury and Tumorigenesis in Mice
The Patatin-Like Phospholipase Domain–Containing 3 148M Variant Exacerbates Alcohol-Induced Liver Injury and Tumorigenesis in Mice Open
View article: Operating performance of middle-deep coaxial borehole heat exchangers based on TRNSYS simulation
Operating performance of middle-deep coaxial borehole heat exchangers based on TRNSYS simulation Open
View article: Utilization of natural products in diverse pathogeneses of diseases associated with single or double DNA strand damage repair
Utilization of natural products in diverse pathogeneses of diseases associated with single or double DNA strand damage repair Open
View article: Cyclization of Two Antimicrobial Peptides Improves Their Activity
Cyclization of Two Antimicrobial Peptides Improves Their Activity Open
One promising strategy to combat worldwide antimicrobial resistance involves using cyclic peptides as antibacterial agents. Cyclization of peptides can confer several advantages, including enhanced stability to proteolysis, decreased toxic…
View article: Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease
Epigenetic regulation-mediated disorders in dopamine transporter endocytosis: A novel mechanism for the pathogenesis of Parkinson's disease Open
Mechanisms such as DNA methylation, histone modifications, and non-coding RNA regulation may impact the endocytosis of dopamine transporter (DAT) by influencing processes like neuronal survival, thereby contributing to the initiation and p…
View article: Clonal origins and divergent evolutionary relationships of synchronous multiple malignant neoplasms in gynecology revealed by next-generation sequencing
Clonal origins and divergent evolutionary relationships of synchronous multiple malignant neoplasms in gynecology revealed by next-generation sequencing Open
View article: Automated assessment of endometrial receptivity for screening recurrent pregnancy loss risk using deep learning-enhanced ultrasound and clinical data
Automated assessment of endometrial receptivity for screening recurrent pregnancy loss risk using deep learning-enhanced ultrasound and clinical data Open
Background Recurrent pregnancy loss (RPL) poses significant challenges in clinical management due to an unclear etiology in over half the cases. Traditional screening methods, including ultrasonographic evaluation of endometrial receptivit…
View article: [Clinical characteristics and prognosis analysis in patients with bone marrow invasive follicular lymphoma].
[Clinical characteristics and prognosis analysis in patients with bone marrow invasive follicular lymphoma]. Open
Objective: This study aimed to summarize the clinical characteristics and prognosis of patients with bone marrow invasive follicular lymphoma (FL) and discuss the treatment modalities. Methods: This study included 183 consecu…
View article: Decreased Memory-Related Regional Cerebral Perfusion in Severe Obstructive Sleep Apnea with a Mild Cognitive Impairment During Wakefulness
Decreased Memory-Related Regional Cerebral Perfusion in Severe Obstructive Sleep Apnea with a Mild Cognitive Impairment During Wakefulness Open
Regions with abnormal perfusion in the NCI and CI groups were mostly memory-related. Blood perfusion in the bilateral inferior temporal and left lingual gyri decreased in the following order: GS > OSA-NCI > OSA-CI. These findings provide b…
View article: Late-Life Alcohol Exposure Does Not Exacerbate Age-Dependent Reductions in Mouse Spatial Memory and Brain TFEB Activity
Late-Life Alcohol Exposure Does Not Exacerbate Age-Dependent Reductions in Mouse Spatial Memory and Brain TFEB Activity Open
Alcohol consumption is believed to affect Alzheimer’s disease (AD) risk, but the contributing mechanisms are not well understood. A potential mediator of the proposed alcohol-AD connection is autophagy, a degradation pathway that maintains…
View article: The role of dsRNA A-to-I editing catalyzed by ADAR family enzymes in the pathogeneses
The role of dsRNA A-to-I editing catalyzed by ADAR family enzymes in the pathogeneses Open
The process of adenosine deaminase (ADAR)-catalyzed double-stranded RNA (dsRNA) Adenosine-to-Inosine (A-to-I) editing is essential for the correction of pathogenic mutagenesis, as well as the regulation of gene expression and protein funct…
View article: How Unnatural Amino Acids in Antimicrobial Peptides Change Interactions with Lipid Model Membranes
How Unnatural Amino Acids in Antimicrobial Peptides Change Interactions with Lipid Model Membranes Open
This study investigates the potential of antimicrobial peptides (AMPs) as alternatives to combat antibiotic resistance, with a focus on two AMPs containing unnatural amino acids (UAAs), E2-53R (16 AAs) and LE-54R (14 AAs). In both peptides…
View article: Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis Open
The incidence of metabolic dysfunction-associated steatohepatitis (MASH) is on the rise, and with limited pharmacological therapy available, identification of new metabolic targets is urgently needed. Oxalate is a terminal metabolite produ…
View article: Optimizing evaluation of endometrial receptivity in recurrent pregnancy loss: a preliminary investigation integrating radiomics from multimodal ultrasound via machine learning
Optimizing evaluation of endometrial receptivity in recurrent pregnancy loss: a preliminary investigation integrating radiomics from multimodal ultrasound via machine learning Open
Background Recurrent pregnancy loss (RPL) frequently links to a prolonged endometrial receptivity (ER) window, leading to the implantation of non-viable embryos. Existing ER assessment methods face challenges in reliability and invasivenes…
View article: Non-Line-of-Sight Positioning Method for Ultra-Wideband/Miniature Inertial Measurement Unit Integrated System Based on Extended Kalman Particle Filter
Non-Line-of-Sight Positioning Method for Ultra-Wideband/Miniature Inertial Measurement Unit Integrated System Based on Extended Kalman Particle Filter Open
In the field of unmanned aerial vehicle (UAV) control, high-precision navigation algorithms are a research hotspot. To address the problem of poor localization caused by non-line-of-sight (NLOS) errors in ultra-wideband (UWB) systems, an U…
View article: Association between anxiety, depression symptoms, and academic burnout among Chinese students: the mediating role of resilience and self-efficacy
Association between anxiety, depression symptoms, and academic burnout among Chinese students: the mediating role of resilience and self-efficacy Open
View article: Hypothalamic sex-specific metabolic shift by canagliflozin during aging
Hypothalamic sex-specific metabolic shift by canagliflozin during aging Open
View article: Unraveling the tumor-promoting role of wildtype Isocitrate dehydrogenase 1 (IDH1) in human gliomas
Unraveling the tumor-promoting role of wildtype Isocitrate dehydrogenase 1 (IDH1) in human gliomas Open
Isocitrate dehydrogenase 1 (IDH1) mutations are discovered in most grade Ⅱ gliomas (71%-78%), grade Ⅲ gliomas (62%-78%) and secondary glioblastomas (88%), and have received lots of attention in recent years. However, the tumor-promoting ro…
View article: Hypothalamic Sex-Specific Metabolic Shift by Canagliflozin during Aging
Hypothalamic Sex-Specific Metabolic Shift by Canagliflozin during Aging Open
The hypothalamus undergoes significant changes with aging and plays crucial roles in age-related metabolic alterations. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are anti-diabetic agents that promote glucose excretion, and promot…
View article: Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome
Mixtures of per- and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome Open
Male fertility has been declining worldwide especially in countries with high levels of endocrine disrupting chemicals (EDCs). Per- and polyfluorinated alkyl Substances (PFAS) have been classified as EDCs and have been linked to adverse ma…
View article: Impact Of Preschool Education Financial Expenditures on The Number of Full-Time Preprimary Teachers in Rural Regions--An Analysis Based on Chinese Provincial Panel Data, 2012-2021
Impact Of Preschool Education Financial Expenditures on The Number of Full-Time Preprimary Teachers in Rural Regions--An Analysis Based on Chinese Provincial Panel Data, 2012-2021 Open
Education is an essential problem concerning the whole society, creating citizens with well-educated is the foundation of a good country. Financial expenditure on education is the basic supplement and support of advanced education. However…