Wanting Chen
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View article: Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation
Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation Open
Procrastination represents one of the most prevalent behavioral problems affecting individual health and societal productivity. Although it is often conceptualized as a form of self-control failure, its underlying neurocognitive mechanisms…
View article: Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation
Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation Open
Procrastination represents one of the most prevalent behavioral problems affecting individual health and societal productivity. Although it is often conceptualized as a form of self-control failure, its underlying neurocognitive mechanisms…
View article: A multi-scale spatial-frequency double branch network for terahertz ISAR image target classification
A multi-scale spatial-frequency double branch network for terahertz ISAR image target classification Open
View article: Association between taurine transporter SLC6A6 and breast cancer development and prognosis: a Mendelian randomization analysis
Association between taurine transporter SLC6A6 and breast cancer development and prognosis: a Mendelian randomization analysis Open
Taurine metabolic reprogramming can serve as a potential marker for early breast cancer diagnosis. SLC6A6 participates in breast cancer progression by regulating taurine levels and influencing immune infiltration, representing an independe…
View article: Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation
Modulating task outcome value to mitigate real-world procrastination via noninvasive brain stimulation Open
Procrastination represents one of the most prevalent behavioral problems affecting individual health and societal productivity. Although it is often conceptualized as a form of self-control failure, its underlying neurocognitive mechanisms…
View article: Relationship Between the Drop Rate of Standing Blood Pressure and Major Adverse Cardiovascular Events
Relationship Between the Drop Rate of Standing Blood Pressure and Major Adverse Cardiovascular Events Open
Orthostatic hypotension (OH) is defined as a decrease of ≥20 mm Hg systolic blood pressure (SBP) or ≥10 mm Hg diastolic blood pressure (DBP) within 3 min after standing. OH was associated with an increased risk of major adverse cardiovascu…
View article: China’s social fake news database release with brain structural, functional, and behavioural measures
China’s social fake news database release with brain structural, functional, and behavioural measures Open
Fake news poses significant societal risks by spreading rapidly on social media. While existing research predominantly examines its propagation patterns and psychological drivers, the neural underpinnings remain insufficiently understood. …
View article: Genetic Markers for Bipolar Disorder in the Taiwanese Popu-lation: Insights from a Genetic Association Study
Genetic Markers for Bipolar Disorder in the Taiwanese Popu-lation: Insights from a Genetic Association Study Open
In recent years, bipolar disorder (BD), a multifaceted mood disorder marked by severe episodic mood fluctuations, has been shown to have an impact on disability-adjusted life-years (DALYs). The increasing prevalence of BD highlights the ne…
View article: Enhancing the Rainfall Forecasting Accuracy of Ensemble Numerical Prediction Systems via Convolutional Neural Networks
Enhancing the Rainfall Forecasting Accuracy of Ensemble Numerical Prediction Systems via Convolutional Neural Networks Open
Ensemble prediction systems are commonly used to demonstrate the potential uncertainty of weather forecasts. These systems also help provide weather predictions to prepare for disasters. Specifically, a type of prediction called a quantita…
View article: Optimizing sparse general matrix–matrix multiplication for DCUs
Optimizing sparse general matrix–matrix multiplication for DCUs Open
Sparse general matrix–matrix multiplication (SpGEMM) is a crucial and complex computational task in many practical applications. Improving the performance of SpGEMM on SIMT processors like modern GPUs is challenging due to the unpredictabl…
View article: Back Cover: Bioinspired Selenium‐Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole‐Scale Medicinal Chemistry and Bioconjugation (Angew. Chem. Int. Ed. 15/2024)
Back Cover: Bioinspired Selenium‐Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole‐Scale Medicinal Chemistry and Bioconjugation (Angew. Chem. Int. Ed. 15/2024) Open
Selenium–nitrogen exchange (SeNEx) chemistry creates seleno-connecting linkage to efficiently explore the organo-Se chemical world. In their Research Article (e202318534), Wei Hou, Hongtao Xu et al. put forward the concept of SeNEx chemist…
View article: Rücktitelbild: Bioinspired Selenium‐Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole‐Scale Medicinal Chemistry and Bioconjugation (Angew. Chem. 15/2024)
Rücktitelbild: Bioinspired Selenium‐Nitrogen Exchange (SeNEx) Click Chemistry Suitable for Nanomole‐Scale Medicinal Chemistry and Bioconjugation (Angew. Chem. 15/2024) Open
Selenium–nitrogen exchange (SeNEx) chemistry creates seleno-connecting linkage to efficiently explore the organo-Se chemical world. In their Research Article (e202318534), Wei Hou, Hongtao Xu et al. put forward the concept of SeNEx chemist…
View article: Progress in Asymmetric Catalytic Synthesis of C—N Axis Chiral Compounds
Progress in Asymmetric Catalytic Synthesis of C—N Axis Chiral Compounds Open
Enantioenriched C-N axial chiral compounds are ubiquitous in many important field, such as natural products, chiral drugs and chiral ligands.Therefore, efficient construction of C-N axis chirality through asymmetric catalytic synthesis has…
View article: PER2 regulates odontoblastic differentiation of dental papilla cells <i>in vitro via</i> intracellular ATP content and reactive oxygen species levels
PER2 regulates odontoblastic differentiation of dental papilla cells <i>in vitro via</i> intracellular ATP content and reactive oxygen species levels Open
Background Dental papilla cells (DPCs) are one of the key stem cells for tooth development, eventually forming dentin and pulp. Previous studies have reported that PER2 is expressed in a 24-hour oscillatory pattern in DPCs in vitro . In vi…
View article: Exploring the risk factors of early sepsis after liver transplantation: development of a novel predictive model
Exploring the risk factors of early sepsis after liver transplantation: development of a novel predictive model Open
Background Sepsis is a severe and common complication of liver transplantation (LT) with a high risk of mortality. However, effective tools for evaluating its risk factors are lacking. Therefore, this study identified the risk factors of e…
View article: Case Report: A de novo NLRP3 variant resulting in autoinflammatory disease in a Chinese newborn
Case Report: A de novo NLRP3 variant resulting in autoinflammatory disease in a Chinese newborn Open
Background Cryopyrin-associated periodic syndromes (CAPS) have been considered autoinflammatory diseases resulting from NLRP3 gene mutations. In recent years, these conditions have been redefined as NLRP3 -associated autoinflammatory disea…
View article: Identification of potential functional peptides involved in demyelinating injury in the central nervous system
Identification of potential functional peptides involved in demyelinating injury in the central nervous system Open
Multiple sclerosis (MS) is a chronic inflammatory neurologic disease characterized by the demyelinating injury of the central nervous system (CNS). It was reported that the mutant peptide came from myelin proteolipid protein (PLP) and myel…
View article: Development of an MCL-1-related prognostic signature and inhibitors screening for glioblastoma
Development of an MCL-1-related prognostic signature and inhibitors screening for glioblastoma Open
Introduction: The effect of the conventional treatment methods of glioblastoma (GBM) is poor and the prognosis of patients is poor. The expression of MCL-1 in GBM is significantly increased, which shows a high application value in targeted…
View article: Genome-Wide Characterization and Gene Expression Analyses of Malate Dehydrogenase (MDH) Genes in Low-Phosphorus Stress Tolerance of Chinese Fir (Cunninghamia lanceolata)
Genome-Wide Characterization and Gene Expression Analyses of Malate Dehydrogenase (MDH) Genes in Low-Phosphorus Stress Tolerance of Chinese Fir (Cunninghamia lanceolata) Open
Malate dehydrogenase (MDH) genes play vital roles in developmental control and environmental stress tolerance in sessile plants by modulating the organic acid–malic acid level. However, MDH genes have not yet been characterized in gymnospe…
View article: 1H-NMR-Based Metabonomics Study to Reveal the Progressive Metabolism Regulation of SAP Deficiency on ApoE−/− Mice
1H-NMR-Based Metabonomics Study to Reveal the Progressive Metabolism Regulation of SAP Deficiency on ApoE−/− Mice Open
Atherosclerosis is the most common disease of the vascular system and the metabolic disorder is one of its important molecular mechanisms. SAP protein is found to be highly expressed in atherosclerotic blood vessels. Our previous study fou…
View article: From fears of evaluation to social anxiety: The longitudinal relationships and neural basis in healthy young adults
From fears of evaluation to social anxiety: The longitudinal relationships and neural basis in healthy young adults Open
Our findings explain the behavioral and neural underpinnings of social anxiety from a fear of evaluation angle. This contributes to a better theorical understanding of SAD and clinical practice.
View article: Detection of a new emerging strain of rabbit haemorrhagic disease virus 2 (GI.2) in China
Detection of a new emerging strain of rabbit haemorrhagic disease virus 2 (GI.2) in China Open
Introduction In May 2020, an outbreak of rabbit haemorrhagic disease 2 (RHD2) caused by the rabbit haemorrhagic disease virus 2 (RHDV2, GI.2) occurred in Sichuan, China. The acute onset and short disease course resulted in rabbit mortality…
View article: Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022)
Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis (Adv. Sci. 26/2022) Open
Meeting Diaryliodonium salts Chemistry with DNA‐Encoded Library DNA‐encoded library (DEL) is a powerful technique for hit discovery in medicinal chemistry. In article number 2202790, Hongtao Xu, Peixiang Ma, Wei Hou, Guang Yang, and co‐wor…
View article: Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis
Metal‐Free and Open‐Air Arylation Reactions of Diaryliodonium Salts for DNA‐Encoded Library Synthesis Open
A successful DNA‐encoded library (DEL) will consist of diverse skeletons and cover chemical space as comprehensive as possible to fully realize its potential in drug discovery and chemical biology. However, the lack of versatile on‐DNA ary…
View article: Methyl Gallate Suppresses the Migration, Invasion, and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells via the AMPK/NF-κB Signaling Pathway in vitro and in vivo
Methyl Gallate Suppresses the Migration, Invasion, and Epithelial-Mesenchymal Transition of Hepatocellular Carcinoma Cells via the AMPK/NF-κB Signaling Pathway in vitro and in vivo Open
Methyl gallate (MG), a polyphenolic compound found in plants, is widely used in traditional Chinese medicine. MG is known to alleviate several cancer symptoms. However, most studies that have reported the antitumor effects of MG have done …
View article: Transformation of Stilbene Glucosides From Reynoutria multiflora During Processing
Transformation of Stilbene Glucosides From Reynoutria multiflora During Processing Open
The root of Reynoutria multiflora Thunb. Moldenke (RM, syn.: Polygonum multiflorum Thunb.) has been widely used in TCM clinical practice for centuries. The raw R. multiflora (RRM) should be processed before use, in order to reduce toxicity…
View article: Development of a real-time TaqMan PCR assay for the detection of porcine circovirus 4
Development of a real-time TaqMan PCR assay for the detection of porcine circovirus 4 Open
Introduction Porcine circovirus 4 (PCV4) was first discovered in 2019 in a herd of pigs with porcine respiratory disease, dermatitis and nephropathy syndrome in Hunan Province, China. It has subsequently been detected in other provinces an…
View article: Maladaptive changes in delay discounting in males during the COVID-19 pandemic: the predictive role of functional connectome
Maladaptive changes in delay discounting in males during the COVID-19 pandemic: the predictive role of functional connectome Open
The Coronavirus disease of 2019 (COVID-19) and measures to curb it created population-level changes in male-dominant impulsive and risky behaviors such as violent crimes and gambling. One possible explanation for this is that the pandemic …
View article: Transcriptome analysis provides insights into the root response of Chinese fir to phosphorus deficiency
Transcriptome analysis provides insights into the root response of Chinese fir to phosphorus deficiency Open
View article: Biofilm characteristics and transcriptomic analysis of Haemophilus parasuis
Biofilm characteristics and transcriptomic analysis of Haemophilus parasuis Open
Haemophilus parasuis (H. parasuis) is a conditional pathogen with the ability to form biofilms which can lead to ineffective drug treatment and severe chronic infections resulting in significant economic losses to the pig industry. Current…