Wan‐Xin Peng
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View article: [Corrigendum] Furin promotes epithelial‑mesenchymal transition in pancreatic cancer cells via Hippo‑YAP pathway
[Corrigendum] Furin promotes epithelial‑mesenchymal transition in pancreatic cancer cells via Hippo‑YAP pathway Open
Following the publication of the above article, the authors drew to the Editor's attention that the image in Fig. 3A on p. 1356 for the 'Migration/BxPC3/sh‑EGFP' experiment was mistakenly presented. This error arose as a consequence of a m…
View article: Loss of YTHDF1 suppresses the progression of malignant rhabdoid tumor of the kidney by regulating Glutathione S-transferase Mu 2 (GSTM2)
Loss of YTHDF1 suppresses the progression of malignant rhabdoid tumor of the kidney by regulating Glutathione S-transferase Mu 2 (GSTM2) Open
In summary, our findings provide new insights into the molecular mechanisms driving MRTK progression, highlighting YTHDF1 and GSTM2 as potential therapeutic targets for this aggressive pediatric renal tumor.
View article: RNA binding protein-mediated competing endogenous RNA mechanism in cancer
RNA binding protein-mediated competing endogenous RNA mechanism in cancer Open
It is evidently now that long non-coding RNAs (lncRNAs) play vital roles in development of cancer through versatile mechanisms. Of importance, lncRNAs play such a regulatory role often through interacting with their partners, including DNA…
View article: Robot-assisted resection of renal tumor in children and comparison with laparoscopic surgery
Robot-assisted resection of renal tumor in children and comparison with laparoscopic surgery Open
Our initial experience suggested that RAS in pediatric renal tumor was feasible and safe, and it reduced surgical trauma and accelerate postoperative recovery for the patients. Due to the limitations of sample size and study quality, the c…
View article: Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567]
Corrigendum to “N6-methyladenosine modified LINC00901 promotes pancreatic cancer progression through IGF2BP2/MYC axis” [Genes & Diseases 10 (2023) 554–567] Open
[This corrects the article DOI: 10.1016/j.gendis.2022.02.014.].
View article: The Silicon Charge Detector of the High Energy Cosmic Radiation Detection facility
The Silicon Charge Detector of the High Energy Cosmic Radiation Detection facility Open
The High Energy cosmic-Radiation Detection facility is a large field-of-view, high-energy cosmic ray experiment planned to be installed on the China Space Station in 2027. The Silicon Charge Detector is a specialized HERD sub-detector aime…
View article: Effective and Efficient Porous CeO2 Adsorbent for Acid Orange 7 Adsorption
Effective and Efficient Porous CeO2 Adsorbent for Acid Orange 7 Adsorption Open
A porous CeO2 was synthesized following the addition of guanidine carbonate to a Ce3+ aqueous solution, the subsequent addition of hydrogen peroxide and a final hydrothermal treatment. The optimal experimental parameters for the synthesis …
View article: Roles of lncRNAs in childhood cancer: Current landscape and future perspectives
Roles of lncRNAs in childhood cancer: Current landscape and future perspectives Open
According to World Health Organization (WHO), cancer is the leading cause of death for children and adolescents. Leukemias, brain cancers, lymphomas and solid tumors, such as neuroblastoma, ostesarcoma and Wilms tumors are the most common …
View article: Roxadustat: Do we know all the answers?
Roxadustat: Do we know all the answers? Open
Anemia is a common complication of chronic kidney disease (CKD), and its prevalence rises as the disease progresses. Intravenous or subcutaneous erythropoiesis-stimulating agents (ESAs) are advised to treat CKD-associated anemia, since sho…
View article: Connecting N6‐methyladenosine modification to ferroptosis resistance in hepatoblastoma
Connecting N6‐methyladenosine modification to ferroptosis resistance in hepatoblastoma Open
Although hepatoblastoma (HB) rarely occurs in adults, it is the most common paediatric malignant liver cancer.1 Prognosis of HB is generally favourable; however, challenges remain for those unresectable tumours and/or chemotherapy resistan…
View article: PRMT5 promotes epithelial‐mesenchymal transition via EGFR‐β‐catenin axis in pancreatic cancer cells
PRMT5 promotes epithelial‐mesenchymal transition via EGFR‐β‐catenin axis in pancreatic cancer cells Open
Protein arginine methyltransferase 5 (PRMT5) has been implicated in the development and progression of human cancers. However, few studies reveal its role in epithelial‐mesenchymal transition (EMT) of pancreatic cancer cells. In this study…
View article: The oncogenic potentials and diagnostic significance of long non‐coding RNA LINC00310 in breast cancer
The oncogenic potentials and diagnostic significance of long non‐coding RNA LINC00310 in breast cancer Open
Recent studies have revealed that long non‐coding RNAs (lncRNAs) are involved in different physiological processes and human diseases. However, to date, the function and overall clinical significance of the vast majority of lncRNAs in brea…
View article: A link between a synonymous SNP and the clinical response to tyrosine kinase inhibitors
A link between a synonymous SNP and the clinical response to tyrosine kinase inhibitors Open
Epidermal growth factor receptor (EGFR) is a member of the large receptor tyrosine kinase (RTK) family. Upon binding to corresponding growth factor ligands, EGFR dimerizes, and triggers intrinsic protein tyrosine kinase activity that regul…
View article: Furin promotes epithelial-mesenchymal transition in pancreatic cancer cells via Hippo-YAP pathway
Furin promotes epithelial-mesenchymal transition in pancreatic cancer cells via Hippo-YAP pathway Open
Furin, a well-characterized proprotein convertase, plays an important role in many diseases and links to tumor metastasis. However, the role of furin in pancreatic cancer progression remains to be elucidated. In the present study, we found…