Meher Rizvi
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View article: Essential Oils as Antimicrobial Agents Against WHO Priority Bacterial Pathogens: A Strategic Review of In Vitro Clinical Efficacy, Innovations and Research Gaps
Essential Oils as Antimicrobial Agents Against WHO Priority Bacterial Pathogens: A Strategic Review of In Vitro Clinical Efficacy, Innovations and Research Gaps Open
The rapid rise of antimicrobial resistance (AMR) has emerged as a critical global health crisis, driven by the widespread emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) pathogens. This growing threat, coupled w…
View article: PREVALENCE OF CHOLELITHIASIS IN PATIENTS DIAGNOSED WITH CHOLELITHIASIS INDICATORS.
PREVALENCE OF CHOLELITHIASIS IN PATIENTS DIAGNOSED WITH CHOLELITHIASIS INDICATORS. Open
This study aimed to assess the prevalence of cholelithiasis in patients diagnosed with cholelithiasis indicators. in a gastroenterology outpatient setting over 3 months from June to August 2024. A total of 69 patients aged 20 to 60 years, …
View article: Antibiotic Resistance and Genetic Determinants of Helicobacter pylori in Oman: Insights from Phenotypic and Whole-Genome Analysis
Antibiotic Resistance and Genetic Determinants of Helicobacter pylori in Oman: Insights from Phenotypic and Whole-Genome Analysis Open
Helicobacter pylori antibiotic resistance data in Oman are limited yet crucial for effective treatment selection. The genetic diversity within H. pylori influences its pathogenicity and clinical outcomes. This study evaluates resistance pa…
View article: Reproductive Autonomy In Immunological Intervention: Ethical Boundaries in Maternal-Fetal Immune Therapy
Reproductive Autonomy In Immunological Intervention: Ethical Boundaries in Maternal-Fetal Immune Therapy Open
Recent advances in immunology have broken barriers in reproductive medicine through immune-modulating therapies that support fertility and pregnancy. Treatments such as intravenous immunoglobulin (IVIG) and intralipid infusions are increas…
View article: EXPLORING THE PREVALENCE AND DEMOGRAPHICS OF LIVER CIRRHOSIS DIR L
EXPLORING THE PREVALENCE AND DEMOGRAPHICS OF LIVER CIRRHOSIS DIR L Open
Background: Liver cirrhosis is a chronic, progressive condition that significantly impacts global health, often coexisting with or mimicking gastrointestinal disorders such as functional dyspepsia. Its burden is increasing in both developi…
View article: Mapping Antimicrobial Resistance in Escherichia coli and Klebsiella pneumoniae from Complicated Urinary Tract Infections in Oman: Phenotypic and Genotypic Insights
Mapping Antimicrobial Resistance in Escherichia coli and Klebsiella pneumoniae from Complicated Urinary Tract Infections in Oman: Phenotypic and Genotypic Insights Open
Background: Mapping the local etiology and susceptibility of common pathogens causing complicated urinary tract infection (cUTI) is important for promoting evidence-based antimicrobial prescribing. Evaluating the prevalence of extended-spe…
View article: Assessment of Phenotypic Tools for Detection of OXA-48, KPC, and NDM in Klebsiella pneumoniae in Oman
Assessment of Phenotypic Tools for Detection of OXA-48, KPC, and NDM in Klebsiella pneumoniae in Oman Open
Background: The alarming increase in carbapenemase-producing Enterobacterales is a matter of grave public health concern. The most ubiquitous carbapenemases, Klebsiella pneumoniae carbapenemase (KPC)-, New Delhi metallo-β-lactamase (NDM)-,…
View article: Mapping Phenotypic and Genotypic Antimicrobial Susceptibility Profile of <em>E. coli</em> and <em>K. pneumoniae</em> in Complicated Urinary Tract Infection in the Era of Mounting Drug Resistance
Mapping Phenotypic and Genotypic Antimicrobial Susceptibility Profile of <em>E. coli</em> and <em>K. pneumoniae</em> in Complicated Urinary Tract Infection in the Era of Mounting Drug Resistance Open
Background: Mapping the local etiology and antimicrobial susceptibility profile of pathogens causing complicated urinary tract infection (cUTI) is important for promoting evidence based antimicrobial prescribing. WGS plays an important rol…
View article: Assessment of Phenotypic Tools for Detection of OXA-48, KPC and NDM in <i>Klebsiella pneumoniae</i> in Oman
Assessment of Phenotypic Tools for Detection of OXA-48, KPC and NDM in <i>Klebsiella pneumoniae</i> in Oman Open
Background: For judicious use of reserve drugs, timely detection of carbapenemases is essential. While molecular tools are gold standard for detection of these enzymes, many laboratories have limited access to them. This study focused on e…
View article: Antimicrobial Susceptibility of Uropathogenic <em>Escherichia coli</em> with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries
Antimicrobial Susceptibility of Uropathogenic <em>Escherichia coli</em> with Analysis of Impact of Socio-Economic Factors in Low, Medium and High-Income Countries Open
Background: While mapping Escherichia coli susceptibility in community acquired simple UTIs across 38 centres, DASH to Protect Antibiotics, (https://dashuti.com/), a multiregional study also assessed impact of socio-economic conditions and…
View article: Regional variations in antimicrobial susceptibility of community-acquired uropathogenic Escherichia coli in India: Findings of a multicentric study highlighting the importance of local antibiograms
Regional variations in antimicrobial susceptibility of community-acquired uropathogenic Escherichia coli in India: Findings of a multicentric study highlighting the importance of local antibiograms Open
Fosfomycin and nitrofurantoin are the preferred oral empirical choices for uncomplicated E. coli cystitis in India, although elevated resistance in some areas is concerning. Empiric use of fluoroquinolones and third-generation cephalospori…
View article: Hypervirulent Capsular Serotypes K1 and K2 Klebsiella pneumoniae Strains Demonstrate Resistance to Serum Bactericidal Activity and Galleria mellonella Lethality
Hypervirulent Capsular Serotypes K1 and K2 Klebsiella pneumoniae Strains Demonstrate Resistance to Serum Bactericidal Activity and Galleria mellonella Lethality Open
Hypervirulent Klebsiella pneumoniae (hvKp) is a variant that has been increasingly linked to severe, life-threatening infections including pyogenic liver abscess and bloodstream infections. HvKps belonging to the capsular serotypes K1 and …
View article: <em>Klebsiella pneumoniae</em> Clinical Strains of Hypervirulent Capsular Serotypes K1 and K2 Demonstrating Resistance against Human Serum Bactericidal Activity and Virulence in Galleria mellonella Model
<em>Klebsiella pneumoniae</em> Clinical Strains of Hypervirulent Capsular Serotypes K1 and K2 Demonstrating Resistance against Human Serum Bactericidal Activity and Virulence in Galleria mellonella Model Open
Hypervirulent Klebsiella pneumoniae (hvKp) is a variant that has been increasingly linked to severe, life threatening infections including pyogenic liver abscess and bloodstream infections. HvKp belonging to the capsular serotypes K1 and K…
View article: P28 Evaluation of one in-house and three commercial phenotypic tests for detection of KPC, NDM and OXA-48-like carbapenemase in <i>Klebsiella pneumoniae</i>: is routine detection possible?
P28 Evaluation of one in-house and three commercial phenotypic tests for detection of KPC, NDM and OXA-48-like carbapenemase in <i>Klebsiella pneumoniae</i>: is routine detection possible? Open
Background Phenotypic characterization of the OXA-48-like carbapenemase XDR and pandrug-resistant (PDR) Klebsiella pneumoniae in clinical isolates is essential for making informed empirical decisions and critical for strengthening antimicr…
View article: Translation and validation of an Urdu version of the Vaccine Attitudes Examination (VAX) scale
Translation and validation of an Urdu version of the Vaccine Attitudes Examination (VAX) scale Open
Introduction Despite being one of the most effective methods of preventing the spread of communicable diseases1, vaccination has been subjected to criticism. Several scales have been formulated that were used to document attitudes towards …
View article: Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with the High Transmissibility of blaKPC Plasmids
Comparative Genomic Analysis Reveals the Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with the High Transmissibility of blaKPC Plasmids Open
Conjugative transposons in Gram-negative bacteria have a significant role in the dissemination of antibiotic-resistance-conferring genes between bacteria. This study aims to genomically characterize plasmids and conjugative transposons car…
View article: Comparative Genomic Analysis Reveals Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with High Transmissibility of blaKPC Plasmids
Comparative Genomic Analysis Reveals Emergence of ST-231 and ST-395 Klebsiella pneumoniae Strains Associated with High Transmissibility of blaKPC Plasmids Open
Conjugative transposons in Gram-negative bacteria have a significant role in the dissemination of antibiotic-resistance-conferring genes between bacteria. This study aims to genomically characterize plasmids and conjugative transposons car…
View article: Evaluation of six commercial and in-house phenotypic tests for detection of AmpC β-lactamases: is routine detection possible?
Evaluation of six commercial and in-house phenotypic tests for detection of AmpC β-lactamases: is routine detection possible? Open
Background Phenotypic characterization of the prevalent AmpC β-lactamases in clinical isolates is essential for making informed empirical decisions and critical for strengthening antimicrobial stewardship programmes. This study focused on …
View article: Exploring Synergistic Combinations in Extended and Pan-Drug Resistant (XDR and PDR) Whole Genome Sequenced Acinetobacter baumannii
Exploring Synergistic Combinations in Extended and Pan-Drug Resistant (XDR and PDR) Whole Genome Sequenced Acinetobacter baumannii Open
Background: The diminishing antimicrobial options for the treatment of XDR and PDR Acinetobacter baumannii is an increasing concern. In this study, we assessed the in vitro synergy of the fosfomycin (FOS) with meropenem (MEM), amikacin (AK…
View article: Cytokine Profile of Scrub Typhus Patients during the Acute Phase of Illness
Cytokine Profile of Scrub Typhus Patients during the Acute Phase of Illness Open
Background: An early and effective immune response has a role in disease presentation and clearance of pathogen. Chemokine and cytokine responses in the immunopathogenesis of scrub typhus (ST) are the least explored aspect. This study aime…
View article: Trends of antimicrobial resistance in patients with complicated urinary tract infection: Suggested empirical therapy and lessons learned from a retrospective observational study in Oman
Trends of antimicrobial resistance in patients with complicated urinary tract infection: Suggested empirical therapy and lessons learned from a retrospective observational study in Oman Open
Background: Complicated urinary tract infection (cUTI) is defined as an infection associated with structural, functional, or metabolic abnormalities of the genitourinary tract. These infections are caused frequently by multidrug-resistant …
View article: Scrub Typhus: An Emerging Etiology among Undiagnosed Febrile Cases in Western Part of Uttar Pradesh, India
Scrub Typhus: An Emerging Etiology among Undiagnosed Febrile Cases in Western Part of Uttar Pradesh, India Open
Scrub typhus is a re-emerging zoonotic rickettsial disease and is prevalent in many parts of India. Scrub typhus in Uttar Pradesh is virtually unknown but has shown emergence in recent reports. In this context, a prospective study was plan…
View article: Assessment of In-Vitro Synergy of Fosfomycin with Meropenem, Amikacin and Tigecycline in Whole Genome Sequenced Extended and Pan Drug Resistant Klebsiella Pneumoniae: Exploring A Colistin Sparing Protocol
Assessment of In-Vitro Synergy of Fosfomycin with Meropenem, Amikacin and Tigecycline in Whole Genome Sequenced Extended and Pan Drug Resistant Klebsiella Pneumoniae: Exploring A Colistin Sparing Protocol Open
Fosfomycin has emerged as a very useful antimicrobial in management of extremely drug resistant (XDR) and pan drug resistant (PDR) Klebsiella pneumoniae. In this study, we assessed in-vitro synergy of colistin sparing combinations of fosfo…