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View article: Novel Methylation‐Based Model for Accurate Diagnosis of Upper Mediastinal Lymph Node Metastasis in Esophagogastric Junction Adenocarcinoma
Novel Methylation‐Based Model for Accurate Diagnosis of Upper Mediastinal Lymph Node Metastasis in Esophagogastric Junction Adenocarcinoma Open
Even after surgical resection, the prognosis is poor for patients with esophagogastric junction adenocarcinoma who develop upper mediastinal lymph node metastasis. Moreover, the current preoperative diagnostic accuracy for upper mediastina…
View article: Impact of Circular Stapler Size on Short‐Term Outcomes and Long‐Term Quality of Life After <scp>McKeown</scp> Esophagectomy
Impact of Circular Stapler Size on Short‐Term Outcomes and Long‐Term Quality of Life After <span>McKeown</span> Esophagectomy Open
Background The circular stapling technique (CST) is reported to be a simple and time‐efficient method; however, it is associated with a high incidence of anastomotic stenosis for McKeown esophagectomy. Meanwhile, the impact of circular sta…
View article: Incidence rates of post-pancreatectomy complications are similar between octogenarians and non-octogenarians and decrease after minimally invasive pancreatic surgery : a retrospective cohort study
Incidence rates of post-pancreatectomy complications are similar between octogenarians and non-octogenarians and decrease after minimally invasive pancreatic surgery : a retrospective cohort study Open
View article: miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5
miR‑100‑5p and miR‑203a‑3p suppress esophageal squamous cell carcinoma progression by targeting FKBP5 Open
Poorly differentiated cancers, including esophageal squamous cell carcinoma (ESCC), exhibit higher malignant potential and worse prognoses than well‑differentiated types. The present study aimed to identify microRNAs (miRNAs or miRs) invol…
View article: Potential of Platelet‐Based Drug Delivery System for Treating Peritoneal Metastasis of Gastric Cancer
Potential of Platelet‐Based Drug Delivery System for Treating Peritoneal Metastasis of Gastric Cancer Open
Peritoneal metastasis is a lethal manifestation of gastric cancer, with poor prognosis and limited treatment options. A targeted drug delivery system minimizing systemic toxicity is urgently needed. Given that platelets form stable aggrega…
View article: Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence
Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence Open
View article: Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis
Evaluation of the details and importance of lymphatic, microvascular, and perineural invasion in patients with non-functioning pancreatic neuroendocrine neoplasms based on tumor size and the 2022 World Health Organization classification: a 23-year retrospective analysis Open
Information on the frequency and role of lymphatic, microvascular, and perineural invasion based on tumor size and malignancy on recurrence may be useful when considering treatment strategies for small- and low-grade NF-PanNENs.
View article: Clinically Adult-Onset Nesidioblastosis with Repeated Severe Hypoglycemia, Successfully Treated by Two Times Pancreatectomies. A Rare Case Report.
Clinically Adult-Onset Nesidioblastosis with Repeated Severe Hypoglycemia, Successfully Treated by Two Times Pancreatectomies. A Rare Case Report. Open
Although nesidioblastosis is the most common cause of hyperinsulinemic hypoglycemia in infants, it is rare in adults. Nesidioblastosis is pathologically characterized by diffuse neoformation of the islets of Langerhans islets from the panc…
View article: Comparison of the influence of postoperative oral nutritional supplementation between octogenarian and non-octogenarian patients undergoing gastrectomy for cancer
Comparison of the influence of postoperative oral nutritional supplementation between octogenarian and non-octogenarian patients undergoing gastrectomy for cancer Open
Postoperative ONS could prevent body weight loss, malnutrition, and sarcopenia especially in octogenarian patients who underwent gastrectomy for gastric cancer.
View article: 270. ANALYSIS OF THE RELATIONSHIP BETWEEN CARDIAC DIAMETER AND ANASTOMOTIC TROUBLE IN TRANS HIATAL ESOPHAGOGASTRIC JUNCTION CANCER SURGERY
270. ANALYSIS OF THE RELATIONSHIP BETWEEN CARDIAC DIAMETER AND ANASTOMOTIC TROUBLE IN TRANS HIATAL ESOPHAGOGASTRIC JUNCTION CANCER SURGERY Open
Background The number of esophagogastric junction (EGJ) cancers has been increasing in recent years, and the trans hiatal lower esophagectomy is widely used for cases with shorter esophageal invasion. However, the mediastinal surgical view…
View article: Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence
Evaluation of the validity of pancreatoduodenectomy in older patients with distal cholangiocarcinoma in terms of recurrence Open
Background This retrospective study investigated the validity of pancreatoduodenectomy (PD) with regard to recurrence in older patients with distal cholangiocarcinoma (DC). Methods We compared 32 patients aged ≥ 75 years and 68 patients ag…
View article: A Case of Pathologically Complete Response After Nivolumab Combined with Chemotherapy in a Gastric Cancer Patient with Virchow’s Lymph Node Metastasis
A Case of Pathologically Complete Response After Nivolumab Combined with Chemotherapy in a Gastric Cancer Patient with Virchow’s Lymph Node Metastasis Open
Gastric cancer with Virchow's lymph node metastasis (LNM) is not indicated for initial curative surgery. Although there have been some case reports of curative resections after pre-operative treatment, including immune checkpoint inhibitor…
View article: Distal Bile Duct Metastasis after Colorectal Cancer Surgery: A Case Report
Distal Bile Duct Metastasis after Colorectal Cancer Surgery: A Case Report Open
大腸癌の遠位胆管転移はまれな病態である．症例は82歳の男性で，80歳時に上行結腸癌，早期胃癌，転移性肝癌に対して回盲部切除，胃部分切除，左肝切除術を施行した．術後補助化学療法としてベバシズマブを併用したS-1+オキサリプラチン療法を行った．術後2年目の経過観察のために施行した腹部造影CTにて遠位胆管に22 mmの造影効果を有する腫瘤を指摘された．MRCPで同部位に欠損像として描出され，PET/CTではFDGの集積が確認された．ERCP下生検で管状腺癌の診断となり，遠位胆管癌…
View article: Evaluation of the Significance of Lymphatic, Microvascular and Perineural Invasion in Patients With Pancreatic Neuroendocrine Neoplasms
Evaluation of the Significance of Lymphatic, Microvascular and Perineural Invasion in Patients With Pancreatic Neuroendocrine Neoplasms Open
Background: Some prognostic factors for pancreatic neuroendocrine neoplasms (PanNENs) have been reported; however, the significance of lymphatic, microvascular, and perineural invasion remains unclear. We aimed to clarify the role of these…
View article: A case of pathologically complete response after preoperative chemotherapy in a pancreatic acinar cell carcinoma patient with portal vein tumor thrombosis
A case of pathologically complete response after preoperative chemotherapy in a pancreatic acinar cell carcinoma patient with portal vein tumor thrombosis Open
Preoperative treatment is being proposed as a standard treatment for pancreatic ductal adenocarcinoma though few cases show a pathologically complete response. On the other hand, there is no consensus regarding preoperative chemotherapy fo…
View article: Evaluation of Early Prognostic Factors in Patients With Pancreatic Ductal Adenocarcinoma Receiving Gemcitabine Together With Nab-paclitaxel
Evaluation of Early Prognostic Factors in Patients With Pancreatic Ductal Adenocarcinoma Receiving Gemcitabine Together With Nab-paclitaxel Open
Background: Gemcitabine together with nab-paclitaxel (GnP) has been shown to improve outcomes in patients with pancreatic ductal adenocarcinoma (PDAC). However, the predictive markers for treatment effects remain unclear. This study aimed …
View article: Correction to: Negative prognostic outcomes of percutaneous transhepatic biliary drainage in distal cholangiocarcinoma: a retrospective analysis using propensity score matching
Correction to: Negative prognostic outcomes of percutaneous transhepatic biliary drainage in distal cholangiocarcinoma: a retrospective analysis using propensity score matching Open
View article: Assessment of Preoperative Clinicophysiologic Findings as Risk Factors for Postoperative Pancreatic Fistula After Pancreaticoduodenectomy
Assessment of Preoperative Clinicophysiologic Findings as Risk Factors for Postoperative Pancreatic Fistula After Pancreaticoduodenectomy Open
Objective Postoperative pancreatic fistula (POPF) is one of the severe complications that develop after pancreaticoduodenectomy (PD). This study aimed to assess the utility of preoperative clinicophysiologic findings as risk factors for PO…
View article: Surgical Outcomes of Perihilar Cholangiocarcinoma - Especially on Postoperative Portal Vein Thrombosis
Surgical Outcomes of Perihilar Cholangiocarcinoma - Especially on Postoperative Portal Vein Thrombosis Open
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Contents Open
View article: Propensity score-matched analysis of internal stent vs external stent for pancreatojejunostomy during pancreaticoduodenectomy: Japanese-Korean cooperative project
Propensity score-matched analysis of internal stent vs external stent for pancreatojejunostomy during pancreaticoduodenectomy: Japanese-Korean cooperative project Open
View article: A Standard Set of Value-Based Patient-Centered Outcomes for Pancreatic Carcinoma: An International Delphi Survey
A Standard Set of Value-Based Patient-Centered Outcomes for Pancreatic Carcinoma: An International Delphi Survey Open
View article: Supplementary Material for: Comparison of Clinicopathological Features of Biliary Neuroendocrine Carcinoma with Adenocarcinoma
Supplementary Material for: Comparison of Clinicopathological Features of Biliary Neuroendocrine Carcinoma with Adenocarcinoma Open
Objective: This study aimed to demonstrate the clinical features and postoperative outcomes of extrahepatic bile duct (EHBD) neuroendocrine carcinoma (NEC) and compared with those of adenocarcinoma. Methods: We …
View article: Evaluation of preoperative risk factors for postpancreatectomy hemorrhage
Evaluation of preoperative risk factors for postpancreatectomy hemorrhage Open
Purpose To investigate the risk factors for post-pancreatectomy hemorrhage (PPH). Methods The incidence, outcome, and risk factors for PPH were evaluated in 1169 patients who underwent pancreatectomy. Results The incidence and mortality ra…
View article: Evaluation of preoperative prognostic factors in patients with resectable pancreatic ductal adenocarcinoma
Evaluation of preoperative prognostic factors in patients with resectable pancreatic ductal adenocarcinoma Open
Objective: Upfront surgery is the standard treatment for resectable pancreatic ductal adenocarcinomas (R-PDACs); however, these tumors often recur. We investigated the factors governing recurrence and prognosis in patients with R-PD…
View article: Is it significant for surgical treatment for gallbladder cancer with jaundice?
Is it significant for surgical treatment for gallbladder cancer with jaundice? Open
View article: Supplementary Material for: Evaluation of the Site and Frequency of Lymph Node Metastasis with Non-Functioning Pancreatic Neuroendocrine Tumor
Supplementary Material for: Evaluation of the Site and Frequency of Lymph Node Metastasis with Non-Functioning Pancreatic Neuroendocrine Tumor Open
Backgrounds: The optimal lymph node dissection range in patients with non-functioning pancreatic neuroendocrine tumors is not yet clear. In this study, we investigated the site and frequency of lymph node metastasis and the s…
View article: Comparison of patients with invasive intraductal papillary mucinous carcinoma and invasive ductal carcinoma of the pancreas: a pathological type- and stage-matched analysis
Comparison of patients with invasive intraductal papillary mucinous carcinoma and invasive ductal carcinoma of the pancreas: a pathological type- and stage-matched analysis Open
Objective: We compared the pathological features and stage-matched outcomes of patients with invasive intraductal papillary mucinous carcinoma (IPMC) and invasive ductal carcinoma (IDC) of the pancreas to identify the reasons for th…
View article: ENBD is associated with decreased tumor dissemination compared to ptbd in perihilar cholangiocarcinoma
ENBD is associated with decreased tumor dissemination compared to ptbd in perihilar cholangiocarcinoma Open
View article: Total Pancreatectomy for a Pancreatic Neuroendocrine Tumor with Agenesis of the Pancreatic Body and Tail
Total Pancreatectomy for a Pancreatic Neuroendocrine Tumor with Agenesis of the Pancreatic Body and Tail Open
症例は50歳,女性.子宮体癌に対して手術予定であり,術前精査の腹部造影CTで膵頭部に早期相で濃染する35mm大の腫瘍と,大動脈左縁より尾側の膵体尾部欠損を認めた.腹部造影MRIでは35mm大のT1低信号,T2高信号,拡散強調画像で高信号を呈する腫瘍性病変であった.血液生化学検査ではHbA1c 6.8%で,その他のホルモン値は基準値内であった.EUS-FNAではクロモグラニンA陽性,シナプトフィジン陽性,Ki-67:10%,であり,非機能性膵神経内分泌腫瘍(pancreati…