Watfa Ahmed
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View article: Beyond hemostasis: Factor VIII deficiency impacts hematopoietic stem cells development in zebrafish
Beyond hemostasis: Factor VIII deficiency impacts hematopoietic stem cells development in zebrafish Open
Introduction Hemophilia A (HA) is a monogenic bleeding disorder caused by coagulation Factor (F) VIII deficiency. Recent studies suggest that FVIII function may extend beyond hemostasis. In a previous study, we utilized morpholino antisens…
View article: Flow Cytometry Evaluation of Blood-Cell-Bound Surface FVIII in Hemophilia A and Thrombosis
Flow Cytometry Evaluation of Blood-Cell-Bound Surface FVIII in Hemophilia A and Thrombosis Open
Hemophilia A (HA) is associated with FVIII coagulation insufficiency or inactivity leading to excessive bleeding. Elevated FVIII, on the contrary, is associated with thrombophilia, thrombosis, myocardial infarctions, and stroke. Active FVI…
View article: Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model
Human immunodeficiency virus infection induces lymphoid fibrosis in the BM-liver-thymus-spleen humanized mouse model Open
A major pathogenic feature associated with HIV infection is lymphoid fibrosis, which persists during antiretroviral therapy (ART). Lymphoid tissues play critical roles in the generation of antigen-specific immune response, and fibrosis dis…