Thomas W. Smith
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View article: Left Atrial Appendage Closure Via Transhepatic Access in a Patient With Congenitally Interrupted Inferior Vena Cava
Left Atrial Appendage Closure Via Transhepatic Access in a Patient With Congenitally Interrupted Inferior Vena Cava Open
Alternate access via a transhepatic approach can be a viable alternative for LAAO when the standard femoral venous approach is prohibitive.
View article: A Literature Review Examining the Potential Role of the ImPACT to Evaluate Probable Concussions in Athletes
A Literature Review Examining the Potential Role of the ImPACT to Evaluate Probable Concussions in Athletes Open
The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is proposed to represent the most widely-used tool for the detection and management of concussions. With the growing rate of concussions in the high school population,…
View article: Impact of Baseline Anteroposterior Mitral Annular Dimensions on Clinical Outcomes after MitraClip for Secondary Mitral Regurgitation
Impact of Baseline Anteroposterior Mitral Annular Dimensions on Clinical Outcomes after MitraClip for Secondary Mitral Regurgitation Open
APMAD was a predictor of adverse outcomes in patients treated with GDMT alone. M-TEER reduced MR severity and the risk of death or HFH regardless of baseline APMAD compared with GDMT alone.
View article: Pathology of Medulloblastoma: Morphologic Features and Molecular Classification
Pathology of Medulloblastoma: Morphologic Features and Molecular Classification Open
This chapter presents an overview of the pathology of medulloblastoma. Historical aspects relating to the origin of medulloblastoma are briefly summarized. The current definition of medulloblastoma presented in the 2021 World Health Organi…
View article: Transcatheter Edge-to-Edge Repair in Patients With Complex Tricuspid Valve Anatomy
Transcatheter Edge-to-Edge Repair in Patients With Complex Tricuspid Valve Anatomy Open
In patients with complex tricuspid anatomies, TEER with the TriClip system demonstrated excellent procedural safety with significant TR reduction and associated improvements in quality of life at 1 year.
View article: A Lab Experiment Involving Free Convection Heat Transfer from a Flat Horizontal Plate
A Lab Experiment Involving Free Convection Heat Transfer from a Flat Horizontal Plate Open
A number of simple modifications were made to an experiment involving free convection heat transfer from a flat horizontal plate to make it safer and more convenient for use in a standard undergraduate laboratory.The experiment was made sa…
View article: Triple versus Double Orifice Valves After Transcatheter Edge-to-Edge Repair: Clinical Features and Outcomes
Triple versus Double Orifice Valves After Transcatheter Edge-to-Edge Repair: Clinical Features and Outcomes Open
Rationale: Procedural and clinical outcomes of triple orifice valves created by mitral valve transcatheter edge-to-edge repair (TEER) have not been previously characterized.
View article: Diffusely invasive supratentorial rosette-forming glioneuronal tumor: illustrative case
Diffusely invasive supratentorial rosette-forming glioneuronal tumor: illustrative case Open
BACKGROUND Rosette-forming glioneuronal tumors (RGNTs) are rare tumors composed of mixed glial and neurocytic components. Most lesions are confined to the posterior fossa, especially in the region of the fourth ventricle, in young adults. …
View article: P-BN07 Identifying gallstones in acute pancreatitis. Are we undermanaging our patients?
P-BN07 Identifying gallstones in acute pancreatitis. Are we undermanaging our patients? Open
Background Acute pancreatitis (AP) is a common surgical presentation with a wide spectrum of severity and outcome. The most common cause of AP is gallstones, accounting for approximately 50% of cases, followed by alcohol excess. Reliable i…
View article: Teaching Unit Ops Lab in the Time of COVID
Teaching Unit Ops Lab in the Time of COVID Open
COVID forced all classroom teachers to significantly modify their teaching methods and embrace the use of videoconferencing.The teaching of engineering labs was even more challenging and led nationwide to alternatives such as do-at-home la…
View article: Papacy, Crusade, and Christian-Muslim Relations
Papacy, Crusade, and Christian-Muslim Relations Open
This book examines the role of the papacy and the crusade in the religious life of the late twelfth through late thirteenth centuries and beyond. Throughout the book, the contributors ask several important questions. Was Innocent III more …
View article: Beholding & Upholding Human Dignity in the Nursing Profession
Beholding & Upholding Human Dignity in the Nursing Profession Open
This work highlights the absence and need for a nursing conceptualization of dignity, including how gaps in the nursing literature inadequately equip the profession to articulate and defend dignity. Essays by the President’s Council for Bi…
View article: Effects of blood pressure and lipid lowering on cognition
Effects of blood pressure and lipid lowering on cognition Open
This study provides Class II evidence that for older people, candesartan plus hydrochlorothiazide, rosuvastatin, or their combination does not significantly affect cognitive decline.
View article: Echocardiographic guidance for transcatheter mitral valve repair using edge-to-edge clip
Echocardiographic guidance for transcatheter mitral valve repair using edge-to-edge clip Open
Percutaneous intervention for mitral valve disease has been established as an alternative to open surgical repair in high risk and inoperable candidates. Edge-to-edge leaflet plication with Mitraclip (Abbott, Menlo Park, CA, USA) is indica…
View article: Early experience with Millipede IRIS transcatheter mitral annuloplasty
Early experience with Millipede IRIS transcatheter mitral annuloplasty Open
The IRIS mitral annuloplasty ring is a transcatheter, transfemoral and transseptal-delivered complete, semi-rigid annuloplasty ring. The IRIS system mimics surgical annuloplasty by reducing the mitral septal-lateral dimension and improving…
View article: Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer
Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer Open
The transfer of tumor-reactive T cells has shown clinical efficacy in a variety of malignancies—notably in the treatment of B cell malignancies—an indication likely to soon receive Food and Drug Administration (FDA) approval as the first e…
View article: Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase
Selective Detection of the D-enantiomer of 2-Hydroxyglutarate in the CSF of Glioma Patients with Mutated Isocitrate Dehydrogenase Open
Purpose: Elevation in D-2-Hydroxyglutarate (D-2HG) has recently emerged as a mandatory byproduct of mutated Isocitrate Dehydrogenase (IDH) genes 1 and 2 in glioma patients. The goal of the present study was to demonstrate the feasibility o…
View article: An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis
An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis Open
Background Multiple sclerosis is an acquired demyelinating disease of the central nervous system. It is the second most common cause of disability in adults in United States after head trauma. Discussion The etiology of MS is probably mult…