Explanipedia

Zika-specific neutralizing antibodies targeting inter-dimer envelope epitopes Open

Rajeshwer S. Sankhala, Vincent Dussupt, Gina Donofrio, Gregory D. Gromowski, Rafael A. De La Barrera , et al. · 2023

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations Open

Vincent Dussupt, Rajeshwer S. Sankhala, Letzibeth Mendez-Rivera, Samantha Townsley, Fabian Schmidt , et al. · 2021

Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor Open

Vincent Dussupt, Rajeshwer S. Sankhala, Gregory D. Gromowski, Gina Donofrio, Rafael A. De La Barrera , et al. · 2020

Causative agent of canine heartworm (Dirofilaria immitis) detected in wild lemurs Open

Sarah Zohdy, Kim Valenta, Bernadette Rabaoarivola, Caitlin J. Karanewsky, Weam I. Zaky , et al. · 2019

Backpack PCR: A point-of-collection diagnostic platform for the rapid detection of Brugia parasites in mosquitoes Open

Weam I. Zaky, Francesca Rachael Tomaino, Nils Pilotte, Sandra J. Laney, Steven A. Williams · 2018

Because this point-of-collection diagnostic platform eliminates reliance on expensive and bulky instrumentation without compromising sensitivity or specificity of detection, it provides an alternative to cost-prohibitive column-dependent D…

Profiling the macrofilaricidal effects of flubendazole on adult female Brugia malayi using RNAseq Open

Maeghan O’Neill, Cristina Ballesteros, Lucienne Tritten, Erica Burkman, Weam I. Zaky , et al. · 2016

The Effects of Ivermectin on Brugia malayi Females In Vitro: A Transcriptomic Approach Open

Cristina Ballesteros, Lucienne Tritten, Maeghan O’Neill, Erica Burkman, Weam I. Zaky , et al. · 2016

These changes provide insight into the mechanisms involved in ivermectin-induced reduction in microfilaria output and impaired fertility, embryogenesis, and larval development.

A Novel Xenomonitoring Technique Using Mosquito Excreta/Feces for the Detection of Filarial Parasites and Malaria Open

Nils Pilotte, Weam I. Zaky, Brian P. Abrams, Dave D. Chadee, Steven A. Williams · 2016

While the operationalizing of excreta/feces testing may require the development of new strategies for sample collection, the high-throughput nature of this new methodology has the potential to greatly reduce MX costs. This will prove parti…

Phenotypic and molecular analysis of the effect of 20-hydroxyecdysone on the human filarial parasite Brugia malayi Open

Amruta S. Mhashilkar, Swamy R. Adapa, Rays H. Y. Jiang, Steven A. Williams, Weam I. Zaky , et al. · 2016

The Effect of In Vitro Cultivation on the Transcriptome of Adult Brugia malayi Open

Cristina Ballesteros, Lucienne Tritten, Maeghan O’Neill, Erica Burkman, Weam I. Zaky , et al. · 2016

These findings suggest that B. malayi can be maintained in culture as a valid system for pharmacological and biological studies, at least for several days after removal from the host and adaptation to the new environment. However, genes en…

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