Weichao Shan
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View article: Serum galectin-3 level increase correlates with poor prognosis in acute coronary syndrome
Serum galectin-3 level increase correlates with poor prognosis in acute coronary syndrome Open
Introduction Levels of galectin-3 (GAL-3), a pro-inflammation biomarker, are closely associated with a diagnosis of acute coronary syndrome (ACS). However, the predictive ability of GAL-3 for long-term adverse prognosis in ACS has not been…
View article: The complex inflammatory indexes predict the prognostic risk for patients with acute coronary syndrome undergoing percutaneous coronary intervention
The complex inflammatory indexes predict the prognostic risk for patients with acute coronary syndrome undergoing percutaneous coronary intervention Open
Introduction An accurate assessment of prognostic risk is widely recognized to be important in improving the survival of patients with acute coronary syndrome (ACS). This study aimed to investigate the roles of neutrophil-to-lymphocyte * p…
View article: Prognostic Effect of pan-Immune-Inflammation Value Indices in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
Prognostic Effect of pan-Immune-Inflammation Value Indices in Patients with Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention Open
Background This study aimed to investigate the association of pan-immune-inflammation value (PIV), PIV/HDL-C (high-density lipoprotein cholesterol), PIV*LDL-C (low-density lipoprotein cholesterol) with the prognosis of patients with acute …
View article: A case report of acute myocardial infarction with hereditary hemorrhagic telangiectasia
A case report of acute myocardial infarction with hereditary hemorrhagic telangiectasia Open
View article: Long-Term Prognostic Value of Adipocytokines in Patients with Acute Coronary Syndrome: An 8-Year Clinical Prospective Cohort Study
Long-Term Prognostic Value of Adipocytokines in Patients with Acute Coronary Syndrome: An 8-Year Clinical Prospective Cohort Study Open
Pro-inflammation adipocytokines RBP4, IL-1β, and MCP-1 increased and anti-inflammation biomarkers ADM, NTN1, and omentin decreased were independently associated with a higher risk of MACEs in patients with ACS.
View article: MicroRNA-195-3p as a potential regulator of hypoxic injury in HUVECs
MicroRNA-195-3p as a potential regulator of hypoxic injury in HUVECs Open
Coronary heart disease is the most common heart disease and is the leading cause of cardiovascular death worldwide. Revascularization methods are considered effective against coronary heart disease However, the mechanism of molecular revas…
View article: Inflammatory biomarkers, angiogenesis and lymphangiogenesis in epicardial adipose tissue correlate with coronary artery disease
Inflammatory biomarkers, angiogenesis and lymphangiogenesis in epicardial adipose tissue correlate with coronary artery disease Open
View article: Potential Mechanism of Andrographolide in Coronary Heart Disease Treatment Based on Network Pharmacology and Molecular Docking
Potential Mechanism of Andrographolide in Coronary Heart Disease Treatment Based on Network Pharmacology and Molecular Docking Open
The potential mechanism of andrographolide in the treatment of coronary heart disease was explored through network pharmacology and molecular docking. The potential targets of andrographolide were predicted by the PharmMapper platform, and…
View article: Associations between serum electrolyte and short-term outcomes in patients with acute decompensated heart failure
Associations between serum electrolyte and short-term outcomes in patients with acute decompensated heart failure Open
http://www.chictr.org.cn/showproj.aspx?proj=23139. Unique identifier: ChiCTR-POC-17014020.
View article: Development of clinical practice ability evaluation scale for new nurses and its reliability and validity
Development of clinical practice ability evaluation scale for new nurses and its reliability and validity Open
Objective: To develop the clinical practice ability evaluation scale for new nurses and test its reliability and validity. Methods: The clinical practice ability prediction test scale of new nurses [1]was formed through literature research…
View article: miR-195-3p/BDNF axis regulates hypoxic injury by targeting P-ERK1/2 expression
miR-195-3p/BDNF axis regulates hypoxic injury by targeting P-ERK1/2 expression Open
Objectives: Coronary heart disease (CHD) is the most common heart disease and the leading cause of cardiovascular deaths worldwide. Decreased endothelial cell (EC) proliferation, increased apoptosis, inflammation, and vascular dysfunction …
View article: Correlation between serum Dickkopf-1 (DKK1) levels and coronary artery stenosis
Correlation between serum Dickkopf-1 (DKK1) levels and coronary artery stenosis Open
View article: Validation and derivation of short-term prognostic risk score in acute decompensated heart failure in China
Validation and derivation of short-term prognostic risk score in acute decompensated heart failure in China Open
View article: Validation and Derivation of short-term prognostic risk score in acute decompensated heart failure in China
Validation and Derivation of short-term prognostic risk score in acute decompensated heart failure in China Open
Background: Few prognostic risk scores (PRSs) have been widely applied in acute decompensated heart failure (ADHF). We therefore externally validated three published PRSs (3A3B, AHEAD, and OPTIME-CHF) and derived a new PRS to predict the s…
View article: MiR-27a-3p/Hoxa10 Axis Regulates Angiotensin II-Induced Cardiomyocyte Hypertrophy by Targeting Kv4.3 Expression
MiR-27a-3p/Hoxa10 Axis Regulates Angiotensin II-Induced Cardiomyocyte Hypertrophy by Targeting Kv4.3 Expression Open
Cardiac hypertrophy is a common pathological process of various cardiovascular diseases, which is often accompanied with structural and electrical remodeling, and can even lead to sudden cardiac death. However, its molecular mechanism stil…
View article: Prognostic value of peripheral blood inflammatory cell subsets in patients with acute coronary syndrome undergoing percutaneous coronary intervention
Prognostic value of peripheral blood inflammatory cell subsets in patients with acute coronary syndrome undergoing percutaneous coronary intervention Open
Objective This study aimed to investigate the predictive value of inflammatory cells in peripheral blood on the prognosis of patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). Methods Patients …
View article: Association between triglyceride glucose index and coronary artery disease with type 2 diabetes mellitus in middle-aged and elderly people
Association between triglyceride glucose index and coronary artery disease with type 2 diabetes mellitus in middle-aged and elderly people Open
This study aimed to investigate the correlation between triglyceride glucose (TyG) index and coronary artery disease (CAD) with type 2 diabetes mellitus (T2DM) and identify the risk associated TyG index in different subgroups. A total of 1…
View article: RETRACTED: Mammalian STE20-Like Kinase 2 Promotes Lipopolysaccharides-Mediated Cardiomyocyte Inflammation and Apoptosis by Enhancing Mitochondrial Fission
RETRACTED: Mammalian STE20-Like Kinase 2 Promotes Lipopolysaccharides-Mediated Cardiomyocyte Inflammation and Apoptosis by Enhancing Mitochondrial Fission Open
In this study, we analyzed the role of mammalian STE20-like protein kinase 2 (Mst2), a serine-threonine protein kinase, in Lipopolysaccharides (LPS)-mediated inflammation and apoptosis in the H9C2 cardiomyocytes. Mst2 mRNA and protein leve…
View article: Association of lymphocyte-to-monocyte ratio with total coronary plaque burden in patients with coronary artery disease
Association of lymphocyte-to-monocyte ratio with total coronary plaque burden in patients with coronary artery disease Open
Background: Lymphocyte-to-monocyte ratio (LMR) is involved in all stages of coronary atherosclerosis and related to coronary artery disease (CAD). However, the correlation between LMR and the coronary plaque burden of CAD is not clearly el…
View article: Association between new circulating proinflammatory and anti-inflammatory adipocytokines with coronary artery disease
Association between new circulating proinflammatory and anti-inflammatory adipocytokines with coronary artery disease Open
The inflammatory adipocytokines GAL-3, RBP4, PTX3, NTN1, and IL-37 were more effective than the classical biomarkers PAI-1 and ADP in the diagnosis and risk assessment of CAD patients.
View article: The study of TrkB pathway on vascular endothelial permeability by regulating the synthesis of VE-cadherin and inhibiting the degradation of VE-cadherin
The study of TrkB pathway on vascular endothelial permeability by regulating the synthesis of VE-cadherin and inhibiting the degradation of VE-cadherin Open
Objective: To investigate the effects and mechanism of tyrosine kinase receptor B (TrkB) on the vascular endothelial permeability. Methods: The counts of FITC-labeled dextran and T cells which were entered through the endothelial monolayer…