Weicheng Hu
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View article: Polysaccharides from lotus root residue alleviate cyclophosphamide-induced immunosuppression in mice
Polysaccharides from lotus root residue alleviate cyclophosphamide-induced immunosuppression in mice Open
View article: Preparation and Characterization of Cyperus-Derived Exosomes Loaded with Selenium Nanoparticles for Selenium Delivery Based on Exosome Protein Quantitation
Preparation and Characterization of Cyperus-Derived Exosomes Loaded with Selenium Nanoparticles for Selenium Delivery Based on Exosome Protein Quantitation Open
Appropriate carriers or templates are crucial for maintaining the stability, biological activity, and bioavailability of selenium nanoparticles (SeNPs). Selecting suitable templates remains challenging for fully utilizing SeNPs functionali…
View article: RNA-seq analysis of shrimp tropomyosin-induced allergic reactions through PI3K/Akt pathway
RNA-seq analysis of shrimp tropomyosin-induced allergic reactions through PI3K/Akt pathway Open
Introduction Tropomyosin (TM) is the primary allergen in Litopenaeus vannamei , which usually causes allergic reactions that may be health or even life-threatening for consumers. Therefore, exploring the sensitization mechanism is of great…
View article: Phenolic constituents in pepper (Piper nigrum L.) berries: UPLC-MS/MS analysis, antioxidant properties, antibacterial activity against Pseudomonas fragi and association analyzed by WCGNA
Phenolic constituents in pepper (Piper nigrum L.) berries: UPLC-MS/MS analysis, antioxidant properties, antibacterial activity against Pseudomonas fragi and association analyzed by WCGNA Open
View article: Piperine Improves <scp>DSS</scp>‐Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota
Piperine Improves <span>DSS</span>‐Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota Open
Inflammatory bowel disease (IBD) is a global health concern with limited therapeutic options. Previous studies have demonstrated that piperine exhibited anti‐inflammatory effects both in vitro and in vivo. However, its potential to amelior…
View article: Ginsenoside Rg2, a principal effective ingredient of Panax ginseng, attenuates DSS-induced ulcerative colitis through NF-κB/NLRP3 pathway
Ginsenoside Rg2, a principal effective ingredient of Panax ginseng, attenuates DSS-induced ulcerative colitis through NF-κB/NLRP3 pathway Open
View article: Ginsenoside F2 from the leaves of Panax ginseng alleviates DSS-induced ulcerative colitis: An in silico analysis and in vivo investigation
Ginsenoside F2 from the leaves of Panax ginseng alleviates DSS-induced ulcerative colitis: An in silico analysis and in vivo investigation Open
View article: Purification and characterization of a novel peroxidase from pepper (Piper nigrum L.)
Purification and characterization of a novel peroxidase from pepper (Piper nigrum L.) Open
View article: A Study on Promotional Shipment Forecasting for E-Commerce Merchants Based on ARIMA Time Series and LSTM Models
A Study on Promotional Shipment Forecasting for E-Commerce Merchants Based on ARIMA Time Series and LSTM Models Open
E-commerce merchants usually want to bear low inventory costs while ensuring that the goods meet the demand, in order to sell a large number of goods, merchants will also carry out a variety of promotional activities, so e-commerce merchan…
View article: The potential of Panax notoginseng against COVID-19 infection
The potential of Panax notoginseng against COVID-19 infection Open
View article: Penazaphilones J–L, Three New Hydrophilic Azaphilone Pigments from Penicillium sclerotiorum cib-411 and Their Anti-Inflammatory Activity
Penazaphilones J–L, Three New Hydrophilic Azaphilone Pigments from Penicillium sclerotiorum cib-411 and Their Anti-Inflammatory Activity Open
Penazaphilones J–L (1–3), three new hydrophilic azaphilone pigments, as well as six known compounds, were discovered from the filamentous fungus Penicillium sclerotiorum cib-411. Compounds 1–3 were structurally elucidated by the detailed i…
View article: Apigenin-7-O-glucoside alleviates DSS-induced colitis by improving intestinal barrier function and modulating gut microbiota
Apigenin-7-O-glucoside alleviates DSS-induced colitis by improving intestinal barrier function and modulating gut microbiota Open
Apigenin-7-O-glucoside (AG), a flavonoid glycoside, has been shown in vitro anti-inflammatory activities. To date, the mechanism of AG against colitis has not been reported. In this study, we investigated the role of AG in relieving coliti…
View article: Phenolic compounds from the flowers of Rosa hugonis Hemsl. and their neuroprotective effects
Phenolic compounds from the flowers of Rosa hugonis Hemsl. and their neuroprotective effects Open
View article: Dammarane-Type Triterpene Saponins from the Roots of Panax Notoginseng (Burk.) F. H. Chen and Their Neuroprotective Effects
Dammarane-Type Triterpene Saponins from the Roots of Panax Notoginseng (Burk.) F. H. Chen and Their Neuroprotective Effects Open
View article: Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells
Ginsenoside F2 enhances glucose metabolism by modulating insulin signal transduction in human hepatocarcinoma cells Open
Overall, GF2 improved glucose metabolism disorders by reducing cellular oxidative stress in IR-HepG2 cells via MAPK signaling, participating in the PI3K/AKT/GSK-3β signaling pathway, promoting glycogen synthesis, and inhibiting gluconeogen…
View article: Systematical Ingredient Investigations of Ficus tikoua Bur. Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions
Systematical Ingredient Investigations of Ficus tikoua Bur. Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions Open
Although the fruit of Ficus tikoua Bur. has been consumed by montanic people in China for centuries, its chemical and biological composition was still unclear. A series of comprehensive investigations on its chemical constituents and bioac…
View article: Systematical Ingredient Investigations of Ficus tikoua Bur. Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions
Systematical Ingredient Investigations of Ficus tikoua Bur. Fruit and Immunoregulatory and Antioxidant Effects of Different Fractions Open
Although the fruit of Ficus tikoua Bur. has been consumed by montanic people in China over centuries, its chemical and biological composition was still unclear. A series of comprehensive investigations on its chemical constituents and bioa…
View article: Effect of extraction technique on chemical compositions and antioxidant activities of freeze-dried green pepper
Effect of extraction technique on chemical compositions and antioxidant activities of freeze-dried green pepper Open
In this study, the yield, content of piperine, and antioxidant activity of pepper oleoresin obtained with the methods of maceration, ultrasound-assisted extraction (UAE), microwave-assisted extraction (MAE), and ultrasound-MAE (UMAE) were …
View article: <i>In Vitro</i> and <i>in Vivo</i> Anti-Inflammatory Activities of <i>Incarvillea Compacta</i> Extract
<i>In Vitro</i> and <i>in Vivo</i> Anti-Inflammatory Activities of <i>Incarvillea Compacta</i> Extract Open
View article: Characterization and antibacterial property of epsilon-poly-L-lysine grafted cellulose films
Characterization and antibacterial property of epsilon-poly-L-lysine grafted cellulose films Open
In order to obtain a stable, biodegradable and cost-effective antibacterial food package materials, this study developed a facile route to immobilize epsilon-poly-L-lysine (EPL) on films. Cellulose films were prepared via a sol-gel transit…
View article: 20-Hydroxy-3-Oxolupan-28-Oic Acid, a Minor Component From Mahonia bealei (Fort.) Carr. Leaves Alleviates Lipopolysaccharide-Induced Inflammatory in Murine Macrophages
20-Hydroxy-3-Oxolupan-28-Oic Acid, a Minor Component From Mahonia bealei (Fort.) Carr. Leaves Alleviates Lipopolysaccharide-Induced Inflammatory in Murine Macrophages Open
20-Hydroxyl-3-oxolupan-28-oic acid (HOA), a minor component from Mahonia bealei (Fort.) Carr. leaves, has been found to attenuate inflammatory responses. However, the underlying molecular mechanism is still unclear. In this study, we perfo…
View article: A review of the immunomodulatory activities of polysaccharides isolated from Panax species
A review of the immunomodulatory activities of polysaccharides isolated from Panax species Open
Panax polysaccharides are biopolymers that are isolated and purified from the roots, stems, leaves, flowers, and fruits of Panax L. plants, which have attracted considerable attention because of their immunomodulatory activit…
View article: Enhancement of skin barrier and hydration-related molecules by protopanaxatriol in human keratinocytes
Enhancement of skin barrier and hydration-related molecules by protopanaxatriol in human keratinocytes Open
View article: Stress Resistance and Pathogenicity of Nonthermal-Plasma-Induced Viable-but-Nonculturable Staphylococcus aureus through Energy Suppression, Oxidative Stress Defense, and Immune-Escape Mechanisms
Stress Resistance and Pathogenicity of Nonthermal-Plasma-Induced Viable-but-Nonculturable Staphylococcus aureus through Energy Suppression, Oxidative Stress Defense, and Immune-Escape Mechanisms Open
The consumer demand for freshness and nutrition has accelerated the development of mild decontamination technologies. The incomplete killing of nonthermal (NT) treatments might induce pathogens to enter into a viable-but-nonculturable (VBN…
View article: Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of <i>Angelica gigas</i> Nakai
Effect of Ultrafine Powderization and Solid Dispersion Formation via Hot-Melt Extrusion on Antioxidant, Anti-Inflammatory, and the Human Kv1.3 Channel Inhibitory Activities of <i>Angelica gigas</i> Nakai Open
Angelica gigas Nakai (AGN) was first processed by ultrafine grinding technology and hot-melt extrusion (HME). The potential antioxidant and anti-inflammatory activities of AGN with a different process were compared, and the effect on the h…
View article: Appraising the Genetic Architecture of Kernel Traits in Hexaploid Wheat Using GWAS
Appraising the Genetic Architecture of Kernel Traits in Hexaploid Wheat Using GWAS Open
Kernel morphology is one of the major yield traits of wheat, the genetic architecture of which is always important in crop breeding. In this study, we performed a genome-wide association study (GWAS) to appraise the genetic architecture of…
View article: Uncovering genomic regions controlling plant architectural traits in hexaploid wheat using GWAS
Uncovering genomic regions controlling plant architectural traits in hexaploid wheat using GWAS Open
Background: Wheat is a staple food crop worldwide. Plant height is a key factor in plant architecture as it plays a crucial role in lodging and thus affects yield and quality. Genome-wide studies are mostly applied in crop plants, due to i…
View article: Characterization of ginsenoside compound K loaded ionically cross-linked carboxymethyl chitosan–calcium nanoparticles and its cytotoxic potential against prostate cancer cells
Characterization of ginsenoside compound K loaded ionically cross-linked carboxymethyl chitosan–calcium nanoparticles and its cytotoxic potential against prostate cancer cells Open
GK-OCMC Nps are potential nanocarriers for delivering hydrophobic drugs, thereby enhancing water solubility and permeability and improving the antiproliferative effects of GK.
View article: Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells
Transcriptome Analyses of the Anti-Proliferative Effects of 20(S)-Ginsenoside Rh2 on HepG2 Cells Open
20(S)-ginsenoside Rh2 (Rh2), a well-known protopanaxadiol-type ginsenoside from Panax ginseng has especially gained attention for its anticancer activities on various types of human cancer cells. However, the molecular mechan…
View article: Structural characterisation and immunomodulatory activity of a polysaccharide isolated from lotus (Nelumbo nucifera Gaertn.) root residues
Structural characterisation and immunomodulatory activity of a polysaccharide isolated from lotus (Nelumbo nucifera Gaertn.) root residues Open