Explanipedia

Integrating molecular generation and fingerprints transferring for single-molecule theranostics targeting endoplasmic reticulum stress Open

Yingli Zhu, Jing Hou, Xiaorong Tan, Weiheng Zhang, Yanpeng Fang , et al. · 2025

This work presents a new paradigm for the intelligent design of fluorescent molecular probes with precise organelle-targeting capabilities for integrated diagnosis and therapy.

Synaptic architecture of a memory engram in the mouse hippocampus Open

Marco Uytiepo, Yongchuan Zhu, Eric A. Bushong, Ken-Ching Chou, Filip S. Polli , et al. · 2025

Memory engrams are formed through experience-dependent plasticity of neural circuits, but their detailed architectures remain unresolved. Using three-dimensional electron microscopy, we performed nanoscale reconstructions of the hippocampa…

Experimental investigation on flexural performance of corroded RC beams with high-strength concrete and steel bars Open

Xiaohui Yu, Ao Yang, Kuangyu Dai, Weiheng Zhang, Dagang Lü , et al. · 2024

The flexural performance of corroded reinforced concrete (RC) beams has been well studied experimentally during the past years. In the available experiments, however, the specimens are commonly designed with the strengths of steel bars and…

Synaptic architecture of a memory engram in the mouse hippocampus Open

Marco Uytiepo, Yongchuan Zhu, Eric A. Bushong, Filip S. Polli, Ken-Ching Chou , et al. · 2024

Memory engrams are formed through experience-dependent remodeling of neural circuits, but their detailed architectures have remained unresolved. Using 3D electron microscopy, we performed nanoscale reconstructions of the hippocampal CA3-CA…

Probabilistic Digital Twin-Informed Risk-Based Inspection Planning for Offshore Wind Turbine Structures Open

Thomas Bull, Daniel Vig Muff, Paul‐Remo Wagner, Weiheng Zhang, Michael Havbro Faber , et al. · 2024

Debris Flow Run-Out Prediction Based on the Shallow-Water Flow Numerical Model—A Case Study of Xulong Gully Open

Yaowu Liu, Dongsheng Zhang, Decun Guo, Wantong He, Weiheng Zhang · 2023

Here we present a method for predicting debris flow run-out based on a numerical model for shallow water flows, using a case study conducted on Xulong Gully, a proposed dam site for a hydropower station in the upper reaches of the Jinsha R…

Long-Term Treatment with Gadopentetic Acid or Gadodiamide Increases TRPC5 Expression and Decreases Adriamycin Nuclear Accumulation in Breast Cancer Cells Open

Weiheng Zhang, Mengyuan Wang, Weizhen Lv, Fletcher A. White, Xingjuan Chen , et al. · 2023

Gadopentetic acid and gadodiamide are paramagnetic gadolinium-based contrast agents (GBCAs) that are routinely used for dynamic contrast-enhanced magnetic resonance imaging (MRI) to monitor disease progression in cancer patients. However, …

Clinical Gait Analysis for Hip Osteoarthritis Diagnostic Model and Arthroplasty Treatment’s Evaluation Open

Weiheng Zhang · 2023

I. Abstract Osteoarthritis (OA) is a degenerative joint disease that seriously disturbs the patients’ motor ability [7]. To quantify gait kinematic impairments from such bone diseases, clinical gait analysis is widely used. Based on the mo…

Long-term treatment with gadopentetic acid or gadodiamide increases TRPC5 expression and decreases adriamycin nuclear accumulation in breast cancer cells Open

Weiheng Zhang, Mengyuan Wang, Weizhen Lv, Fletcher A. White, Xingjuan Chen , et al. · 2023

Gadopentetic acid and gadodiamide are paramagnetic gadolinium-based contrast agents (GBCAs) that are routinely used for dynamic contrast-enhanced magnetic resonance imaging (MRI) to monitor disease progression in cancer patients. However, …

Methodological survey of using Bayesian Network for predicting pharmacology-based bioactivities of Chinese medicines: a scoping review Open

Zi-Xin Han, Chunyu Wang, Jiayin Wei, Can-Jie Huang, Weiheng Zhang , et al. · 2023

Towards resilience of offshore wind farms: A framework and application to asset integrity management Open

Min Liu, Jianjun Qin, Dagang Lü, Weiheng Zhang, Jiangsheng Zhu , et al. · 2022

Distribution and Characteristics of Damming Landslides Triggered by 1920 M~8 Haiyuan Earthquake, NW China Open

Weiheng Zhang, Yueren Xu, Xinyi Guo, Wenqiao Li, Peng Du , et al. · 2022

Earthquake-triggered damming landslides threaten downstream residents and affect the regional landscape by disrupting water and sediment fluxes. Therefore, it is essential to study the distribution characteristics and distinctive controlli…

Understanding historical earthquakes by mapping coseismic landslides in the Loess Plateau, northwest China Open

Yueren Xu, Jing Liu‐Zeng, Mark B. Allen, Peng Du, Weiheng Zhang , et al. · 2022

Locating the epicenters and quantifying the magnitudes of historical earthquakes are important, yet difficult, tasks. These tasks often entail estimating seismic intensities based on written documentation, which suffers from biases and unc…

mTBI-Induced Systemic Vascular Dysfunction in a Mouse mTBI Model Open

Weizhen Lv, Zhuang Wang, Hanxue Wu, Weiheng Zhang, Jiaxi Xu , et al. · 2022

Mild traumatic brain injury (mTBI) without skull fracturing is the most common occurrence of all TBIs and is considered as a serious public health concern. Animal models of mTBI are essential to investigation of TBI and its effects. In the…

Value of information analysis in civil and infrastructure engineering: a review Open

Weiheng Zhang, Dagang Lü, Jianjun Qin, Sebastian Thöns, John Dalsgaard Sørensen · 2021

The concept of Value of Information (VoI) has attracted significant attentions within the civil engineering community over especially the last decade. Triggered by the increasing focus on structural health monitoring, availability of data …

Nanoscale 3D EM reconstructions reveal intrinsic mechanisms of structural diversity of chemical synapses Open

Yongchuan Zhu, Marco Uytiepo, Eric A. Bushong, Matthias G. Haberl, Elizabeth Beutter , et al. · 2021

Incremental shortening calculation of the mixed-shear fault-bend folds Open

Weiheng Zhang, Jie Chen, Tao Li · 2021

<p>Shear fault-bend folds are characterized by a long back-limb that dips more gently than the fault ramp [1]. During the folding growth, the back limb rotates and widens progressively through a combination of limb rotation and kink-…

Landslides of the 1920 Haiyuan earthquake, northern China Open

Yueren Xu, Jing Liu‐Zeng, Mark B. Allen, Weiheng Zhang, Peng Du · 2020

The great M ~ 8 1920 Haiyuan earthquake (HYEQ) was one of the largest and most deadly earthquakes in China in the last century, with ~ 234,000 deaths. The earthquake occurred within the Loess Plateau of northern China, where Quaternary loe…

Multi-Depot Green Vehicle Routing Problem to Minimize Carbon Emissions Open

Weiheng Zhang, Yuvraj Gajpal, S. S. Appadoo, Wei Qi · 2020

A Multi-Depot Green Vehicle Routing Problem (MDGVRP) is considered in this paper. In MDGVRP, Alternative Fuel-powered Vehicles (AFVs) start from different depots, serve customers, and, at the end, return to the original depots. The limited…

Landslide characteristics in the Loess Plateau, northern China Open

Yueren Xu, Mark B. Allen, Weiheng Zhang, Wenqiao Li, Honglin He · 2020

Nanoscale 3D EM Reconstructions Reveal Intrinsic Mechanisms of Structural Diversity of Chemical Synapses Open

Yongchuan Zhu, Marco Uytiepo, Eric A. Bushong, Matthias G. Haberl, Elizabeth Beutter , et al. · 2020

Life Cycle Management of Structural Systems Based on the Optimal SHM Strategy by VoI Analysis Open

Weiheng Zhang, Dagang Lü, Jianjun Qin, Michael Havbro Faber · 2019

Structural health monitoring (SHM) has been widely installed on critical infrastructure, such as buildings, bridges, dams, etc., which are very beneficial for optimal life-cycle decision making. However, the identification of how to implem…

Weiheng Zhang YOU? Author Swipe