2025-10-10
Safety and effectiveness of lecanemab in Chinese patients with early Alzheimer’s disease: Evidence from a multidimensional real-world study
2025-10-10 • Wenyan Kang, Chao Gao, Xiaoyan Li, Xiaoxue Wang, Huizhu Zhong, Wei Qiao, Yonghua Tang, Peijian Huang, Ruinan Shen, Lingyun Chen, Jing Zhang, Rong F...
Abstract Introduction: Lecanemab has shown promise in treating early Alzheimer’s disease (AD), but its safety and efficacy in Chinese populations remain unexplored. This study aimed to evaluate the safety and 6-month clinical outcomes of lecanemab in Chinese patients with mild cognitive impairment (MCI) or mild AD. Methods: In this single-arm, real-world study, participants with MCI due to AD or mild AD received biweekly intravenous lecanemab (10 mg/kg). The study was conducted at Hainan Branch, Ruijin Hospital Sh…