Weijia Kong
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View article: Impact of Oxygen Plasma Surface Treatment on Photoresist Adhesion in BaTiO3-Based Photonic Device Fabrication
Impact of Oxygen Plasma Surface Treatment on Photoresist Adhesion in BaTiO3-Based Photonic Device Fabrication Open
Oxygen-plasma pre-cleans are routine before fabrication, but on BaTiO3 thin films we observed catastrophic photoresist lift-off during mild rinsing and sonication. To explain the failure, we combined optical microscopy, EDS, and XPS. EDS s…
View article: Protoplast isolation and transient expression in the precious and economically important tree Toona ciliata
Protoplast isolation and transient expression in the precious and economically important tree Toona ciliata Open
The established protoplast isolation and transient expression system provides a foundation for the subsequent identification of gene function and mechanism research, and provides a reliable research platform for the molecular breeding of T…
View article: Visualization-Based Rapid Screening and Quantitative Analysis of Target Peptides for Meat Authentication
Visualization-Based Rapid Screening and Quantitative Analysis of Target Peptides for Meat Authentication Open
Amidst growing demand for meat products, concerns regarding their authenticity and safety have intensified, primarily due to potential fraudulent substitutions of cheaper meats, which are not accurately labeled. This study presents a novel…
View article: Macrophage-derived KIF13B interacts with USP9X to attenuate abdominal aortic aneurysm development by potentiating TFEB stability
Macrophage-derived KIF13B interacts with USP9X to attenuate abdominal aortic aneurysm development by potentiating TFEB stability Open
Rationale: Abdominal aortic aneurysm (AAA) is a highly lethal cardiovascular disorder for which there is no effective medication to date. Kinesin family member 13b (KIF13B), a vital motor protein, has been recently identified as a n…
View article: Abnormal expression of Hippo–YAP1 signalling pathway and progesterone resistance mechanism in endometrial polyps
Abnormal expression of Hippo–YAP1 signalling pathway and progesterone resistance mechanism in endometrial polyps Open
EPs have progesterone resistance, and the Hippo-YAP1 signalling pathway may be involved in the development and progression of EPs by acting on the progesterone resistance mechanism.
View article: Impact of antral resection margin distance from the pylorus in sleeve gastrectomy: A systematic review and meta-analysis on therapeutic efficacy
Impact of antral resection margin distance from the pylorus in sleeve gastrectomy: A systematic review and meta-analysis on therapeutic efficacy Open
View article: Polymer‐Driven Co‐Assembly of Achiral and Chiral Nanoparticles into Plasmonic Nanoclusters with Quantitatively Modulated Optical Chirality
Polymer‐Driven Co‐Assembly of Achiral and Chiral Nanoparticles into Plasmonic Nanoclusters with Quantitatively Modulated Optical Chirality Open
Chiral plasmonic nanoassemblies demonstrate enhanced chiral optical activity through plasmonic mode coupling, holding transformative potential for applications in sensing, catalysis, and quantum‐optical technologies. However, the mechanism…
View article: [The diagnostic strategy, procedure and pathway for acute vestibular syndrome SCD].
[The diagnostic strategy, procedure and pathway for acute vestibular syndrome SCD]. Open
Acute vestibular syndrome（AVS） accounts for about 5% of walk clinic, and 20% of neurology consultations in the emergency department. A central acute vestibular syndrome is of high-risk vertigo disorders or potentially life-threaten…
View article: LESS IS MORE: classified management of hypertriglyceridemia-induced acute pancreatitis on the basis of a propensity score matching cohort study
LESS IS MORE: classified management of hypertriglyceridemia-induced acute pancreatitis on the basis of a propensity score matching cohort study Open
HTG-AP patients with very severe hypertriglyceridemia may be treated safely and effectively with insulin and heparin, potentially offering a more cost-effective treatment approach. Similarly, patients with severe hypertriglyceridemia might…
View article: Hearing loss and pathological changes of cochlea in a mouse model carrying compound heterozygous variants in the <i>Gjb2</i> non‐coding region
Hearing loss and pathological changes of cochlea in a mouse model carrying compound heterozygous variants in the <i>Gjb2</i> non‐coding region Open
Background GJB2 gene variants are the most important cause of sensorineural hearing loss. A large number of clinical studies have focused on coding region variants, and a significant proportion of patients with single coding region variant…
View article: Advancing Preoperative Diagnosis: Case Report and Imaging Analysis of Cervical Spine Tenosynovial Giant Cell Tumor
Advancing Preoperative Diagnosis: Case Report and Imaging Analysis of Cervical Spine Tenosynovial Giant Cell Tumor Open
BACKGROUND Tenosynovial giant cell tumor (TGCT) is a rare, benign, yet aggressive, lesion, usually involving a bursa or the tendon sheath. Spinal TGCT is quite rare. Its appearance on imaging can mimic other aggressive diseases, including …
View article: A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement
A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement Open
Hearing is one of the most vital sensory functions in human beings and a crucial means of perceiving and acquiring information from the natural environment. The advancement of human society is closely linked to the development of language,…
View article: Evaluation of Safety and Effectiveness of the LISTENT LCI-20PI Cochlear Implant in Post-Lingually Deafened Individuals
Evaluation of Safety and Effectiveness of the LISTENT LCI-20PI Cochlear Implant in Post-Lingually Deafened Individuals Open
Background: Cochlear implantation is safe and effective in restoring hearing and speech recognition abilities for individuals with severe to profound sensorineural hearing loss. This prospective multicenter clinical trial was conducted to …
View article: Simultaneous Detection of Mir-133a and Atp in Living Cells for Real-Time Assessment of Muscle Injury
Simultaneous Detection of Mir-133a and Atp in Living Cells for Real-Time Assessment of Muscle Injury Open
View article: Neoadjuvant-Adjuvant Chemoimmunotherapy Provides Significant Benefits for Individuals with Non-Small-Cell Lung Cancer Compared to Chemotherapy Alone, Showing Differences of Benefits in Pathological Stage and PD-L1 Score
Neoadjuvant-Adjuvant Chemoimmunotherapy Provides Significant Benefits for Individuals with Non-Small-Cell Lung Cancer Compared to Chemotherapy Alone, Showing Differences of Benefits in Pathological Stage and PD-L1 Score Open
View article: Discovery of Novel Benzyl Indole Histone Deacetylase Inhibitors for Efficient Treatment of Colorectal Cancer
Discovery of Novel Benzyl Indole Histone Deacetylase Inhibitors for Efficient Treatment of Colorectal Cancer Open
View article: Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional <i>Gjb2</i> Null Mice Model
Viral‐Mediated Connexin 26 Expression Combined with Dexamethasone Rescues Hearing in a Conditional <i>Gjb2</i> Null Mice Model Open
GJB2 encodes connexin 26 (Cx26), the most commonly mutated gene causing hereditary non‐syndromic hearing loss. Cx26 is mainly expressed in supporting cells (SCs) and fibrocytes in the mammalian cochlea. Gene therapy is currently considered…
View article: Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage
Inhibition of the cGAS‑STING Pathway Reduces Cisplatin-Induced Inner Ear Hair Cell Damage Open
View article: Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery
Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery Open
Venous malformations (VMs) represent prevalent vascular anomalies typically attributed to non-inherited somatic mutations within venous endothelial cells (VECs). The lack of robust disease models for VMs impedes drug discovery. Here, we de…
View article: [SCD programmatic diagnostic strategy and diagnostic pathway for vertigo disease].
[SCD programmatic diagnostic strategy and diagnostic pathway for vertigo disease]. Open
Vertigo （or dizziness） is one of the most common symptoms in clinical practice. The misdiagnosis rate of vertigo diseases is high due to the factors that vertigo disorders involve multiple systems and organs throughout the body wit…
View article: Regional Operation of Electricity-Hythane Integrated Energy System Considering Coupled Energy and Carbon Trading
Regional Operation of Electricity-Hythane Integrated Energy System Considering Coupled Energy and Carbon Trading Open
The deepening implementation of the energy and carbon market imposes trading requirements on multiple regional integrated energy system participants, including power generation plants, industrial users, and carbon capture, utilization, and…
View article: [The VeSFADS structural classification of vestibular disorders].
[The VeSFADS structural classification of vestibular disorders]. Open
The issuing of International Classification of Vestibular Disorders（ICVD） by Brny society（2015） greatly facilitates the progress of vestibular medicine. The syndromic classification of vestibular disorders by ICVD enable the phys…
View article: Polygenic Risk Score Modifies the Association of HbA1c With Hearing Loss in Middle-Aged and Older Chinese Individuals: The Dongfeng-Tongji Cohort
Polygenic Risk Score Modifies the Association of HbA1c With Hearing Loss in Middle-Aged and Older Chinese Individuals: The Dongfeng-Tongji Cohort Open
OBJECTIVE Evidence regarding the modifying effect of the polygenic risk score (PRS) on the associations between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these associations can be influenced by genetic …
View article: Polygenic risk score modifies the association of HbA1c with hearing loss in middle-aged and older Chinese: The Dongfeng-Tongji cohort
Polygenic risk score modifies the association of HbA1c with hearing loss in middle-aged and older Chinese: The Dongfeng-Tongji cohort Open
Objective: Evidence regarding the modifying effect of polygenic risk score (PRS) on the association between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these association can be influenced by genetic susce…
View article: Polygenic risk score modifies the association of HbA1c with hearing loss in middle-aged and older Chinese: The Dongfeng-Tongji cohort
Polygenic risk score modifies the association of HbA1c with hearing loss in middle-aged and older Chinese: The Dongfeng-Tongji cohort Open
Objective: Evidence regarding the modifying effect of polygenic risk score (PRS) on the association between glycemic traits and hearing loss (HL) was lacking. We aimed to examine whether these association can be influenced by genetic susce…
View article: The Integration of Transcriptome and Metabolome Analyses Provides Insights into the Determinants of the Wood Properties in Toona ciliata
The Integration of Transcriptome and Metabolome Analyses Provides Insights into the Determinants of the Wood Properties in Toona ciliata Open
Toona ciliata, also known as Chinese mahogany, is a high-quality and fast-growing wood species with a high economic value. The wood properties of T. ciliata of different provenances vary significantly. In this study, we conducted comprehen…
View article: Clinical practice guidelines for gene therapy to treat hereditary hearing loss
Clinical practice guidelines for gene therapy to treat hereditary hearing loss Open
Hereditary deafness is a common neurosensory disorder, and 148 non‐syndromic deafness genes have been identified to date. Gene therapy has been used to treat a variety of genetic diseases, but no gene therapy drug for hereditary deafness h…
View article: Lercanidipine’s Antioxidative Effect Prevents Noise-Induced Hearing Loss
Lercanidipine’s Antioxidative Effect Prevents Noise-Induced Hearing Loss Open
Noise-induced hearing loss (NIHL) is a prevalent form of adult hearing impairment, characterized by oxidative damage to auditory sensory hair cells. Although certain dihydropyridines, the L-type calcium channel blockers, exhibit protective…
View article: Analysis of expression pattern and prognostic value of the HPSE in breast cancer through CD274/CTLA-4 immune checkpoint proteins
Analysis of expression pattern and prognostic value of the HPSE in breast cancer through CD274/CTLA-4 immune checkpoint proteins Open
Heparanase (HPSE), an endoglycosidase that cleaves heparan sulfate, regulates various biological processes related to tumor progression. In the study, we further explored the prognostic value of HPSE through the TCGA database. Our model de…
View article: Heparinase III cleaved HS promotes vasculogenic mimicry in Triple Negative Breast Cancer via VEGFA signaling
Heparinase III cleaved HS promotes vasculogenic mimicry in Triple Negative Breast Cancer via VEGFA signaling Open
Anti-angiogenic therapy sometimes triggers alternative vasculogenic mimicry, which is a predictor of poor prognosis. Researches on angiogenesis and vasculogenic mimicry double-related targets and the mechanism behind them could help with t…