Wei‐Jung Chen
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View article: The Impact of Fermented Gamma-Aminobutyric Acid on Poultry Growth Performance Through Insulin-like Growth Factor-1 Activation
The Impact of Fermented Gamma-Aminobutyric Acid on Poultry Growth Performance Through Insulin-like Growth Factor-1 Activation Open
Gamma-aminobutyric acid (GABA) is becoming more well-acknowledged for its ability to improve the development performance of poultry, particularly by interacting with the Insulin-like growth Factor 1 (IGF-1) pathway. This review emphasizes …
View article: Effect of Antimicrobial Peptide Q4-15-2A7P on Growth Performance, Gut Morphology, Intestinal Gene Expression, and Ileal Microbiota in Broilers Challenged with Clostridium perfringens Toxin
Effect of Antimicrobial Peptide Q4-15-2A7P on Growth Performance, Gut Morphology, Intestinal Gene Expression, and Ileal Microbiota in Broilers Challenged with Clostridium perfringens Toxin Open
This study investigated the effects of antimicrobial peptide Q4-15-2A7P on the growth performance and gut health of broilers under Clostridium perfringens toxin challenge. A total of 144 one-day-old broiler chicks (Ross 308) were assigned …
View article: CDGSH iron-sulfur domain 2 as a therapeutic target for stroke: an opinion article
CDGSH iron-sulfur domain 2 as a therapeutic target for stroke: an opinion article Open
OPINION article Front. Mol. Neurosci., 28 May 2024Sec. Brain Disease Mechanisms Volume 17 - 2024 | https://doi.org/10.3389/fnmol.2024.1386118
View article: Editorial: The legacy of Dr. Rita Levi-Montalcini: advances in neurotrophic factors in brain disease development and treatment
Editorial: The legacy of Dr. Rita Levi-Montalcini: advances in neurotrophic factors in brain disease development and treatment Open
EDITORIAL article Front. Mol. Neurosci., 25 April 2024Sec. Brain Disease Mechanisms Volume 17 - 2024 | https://doi.org/10.3389/fnmol.2024.1387026
View article: Management and control of coccidiosis in poultry — A review
Management and control of coccidiosis in poultry — A review Open
Poultry coccidiosis is an intestinal infection caused by an intracellular parasitic protozoan of the genus Eimeria. Coccidia-induced gastrointestinal inflammation results in large economic losses, hence finding methods to decrease its prev…
View article: Impact of gut–brain interaction in emerging neurological disorders
Impact of gut–brain interaction in emerging neurological disorders Open
The central nervous system (CNS) is a reservoir of immune privilege. Specialized immune glial cells are responsible for maintenance and defense against foreign invaders. The blood-brain barrier (BBB) prevents detrimental pathogens and pote…
View article: Surfactin Containing Bacillus licheniformis-Fermented Products Alleviate Dextran Sulfate Sodium-Induced Colitis by Inhibiting Colonic Inflammation and the NLRP3 Inflammasome in Mice
Surfactin Containing Bacillus licheniformis-Fermented Products Alleviate Dextran Sulfate Sodium-Induced Colitis by Inhibiting Colonic Inflammation and the NLRP3 Inflammasome in Mice Open
Inflammatory bowel disease (IBD) is a non-infectious disease characterized by chronic inflammation of the gastrointestinal tract. Currently, management of IBD is still a clinical challenge. The purpose of this study was to investigate the …
View article: Homogeneous Chronic Subdural Hematoma with Diverse Recurrent Possibilities
Homogeneous Chronic Subdural Hematoma with Diverse Recurrent Possibilities Open
Background: Evidence suggests that hyperdense (HD) chronic subdural hematomas (CSDHs) have a higher recurrence than hypodense (LD) chronic subdural hematomas. The value of mean hematoma density (MHD) has been proven to be associated with p…
View article: Antibacterial and Anticancer Activities of Pleurocidin-Amide, a Potent Marine Antimicrobial Peptide Derived from Winter Flounder, Pleuronectes americanus
Antibacterial and Anticancer Activities of Pleurocidin-Amide, a Potent Marine Antimicrobial Peptide Derived from Winter Flounder, Pleuronectes americanus Open
The extensive use of conventional antibiotics has led to the growing emergence of many resistant strains of pathogenic bacteria. Evidence suggests that cationic antimicrobial peptides (AMPs) have the greatest potential to serve as traditio…
View article: Anti-Inflammatory CDGSH Iron-Sulfur Domain 2: A Biomarker of Central Nervous System Insult in Cellular, Animal Models and Patients
Anti-Inflammatory CDGSH Iron-Sulfur Domain 2: A Biomarker of Central Nervous System Insult in Cellular, Animal Models and Patients Open
Spinal cord injury (SCI) promotes brain inflammation; conversely, brain injury promotes spinal neuron loss. There is a need to identify molecular biomarkers and therapeutic targets for central nervous system (CNS) injury. CDGSH iron-sulfur…
View article: Development and validation the efficacy of Bacillus-based fermented products as an antibiotics alternative in domestic animals
Development and validation the efficacy of Bacillus-based fermented products as an antibiotics alternative in domestic animals Open
Intestinal microflora plays a critical role in the process of nutrient digestion and immunomodulation. Normal gut microbiota is responsible for resistance to colonization by exogenous pathogenic microorganisms. Pathogen invasion alters the…
View article: Freshwater Clam Extract Mitigates Neuroinflammation and Amplifies Neurotrophic Activity of Glia: Insights from In Vitro Model of Neurodegenerative Pathomechanism
Freshwater Clam Extract Mitigates Neuroinflammation and Amplifies Neurotrophic Activity of Glia: Insights from In Vitro Model of Neurodegenerative Pathomechanism Open
Background. An extensive body of research suggests that brain inflammation and oxidative stress are the underlying causes of Parkinson’s disease (PD), for which no potent therapeutic approach exists to mitigate the degradation of dopamine …
View article: Effectiveness of Bacillus licheniformis-Fermented Products and Their Derived Antimicrobial Lipopeptides in Controlling Coccidiosis in Broilers
Effectiveness of Bacillus licheniformis-Fermented Products and Their Derived Antimicrobial Lipopeptides in Controlling Coccidiosis in Broilers Open
This study aimed to investigate the potential of Bacillus licheniformis-fermented products (BLFP) and their derived antimicrobial lipopeptide, surfactin, for the prevention of coccidiosis in broilers. Broilers were fed BLFP at 1.25 and 5 g…
View article: Effect of Fermented Products Produced by Bacillus licheniformis on the Growth Performance and Cecal Microbial Community of Broilers under Coccidial Challenge
Effect of Fermented Products Produced by Bacillus licheniformis on the Growth Performance and Cecal Microbial Community of Broilers under Coccidial Challenge Open
This study investigated the effects of fermented products produced by Bacillus licheniformis (fermented products) on the growth performance and cecal microbial community in broilers exposed to coccidial challenge. A total of 108 one-day-ol…
View article: Antibacterial and Antibiofilm Activities of Novel Antimicrobial Peptides against Multidrug-Resistant Enterotoxigenic Escherichia Coli
Antibacterial and Antibiofilm Activities of Novel Antimicrobial Peptides against Multidrug-Resistant Enterotoxigenic Escherichia Coli Open
Post-weaning diarrhea due to enterotoxigenic Escherichia coli (ETEC) is a common disease of piglets and causes great economic loss for the swine industry. Over the past few decades, decreasing effectiveness of conventional antibiotics has …
View article: The effect of different colored light emitting diode illumination on egg laying performance, egg qualities, blood hormone levels and behavior patterns in Brown Tsaiya duck
The effect of different colored light emitting diode illumination on egg laying performance, egg qualities, blood hormone levels and behavior patterns in Brown Tsaiya duck Open
Objective: The objective of this experiment was to investigate the effects of different colors produced by light emitting diode (LED) on Brown Tsaiya ducks.Methods: A total of 144 female Brown Tsaiya ducks were randomly allocated into thre…
View article: The Effect of Bacillus licheniformis-Fermented Products and Postpartum Dysgalactia Syndrome on Litter Performance Traits, Milk Composition, and Fecal Microbiota in Sows
The Effect of Bacillus licheniformis-Fermented Products and Postpartum Dysgalactia Syndrome on Litter Performance Traits, Milk Composition, and Fecal Microbiota in Sows Open
This study was designed to evaluate the effects of Bacillus licheniformis-fermented products (BLFP) and postpartum dysgalactia syndrome (PDS) on litter performance traits, milk composition, and fecal microbiota in sows in a commercial farr…
View article: Bacillus licheniformis-Fermented Products Reduce Diarrhea Incidence and Alter the Fecal Microbiota Community in Weaning Piglets
Bacillus licheniformis-Fermented Products Reduce Diarrhea Incidence and Alter the Fecal Microbiota Community in Weaning Piglets Open
Prophylactic use of antibiotics in-feed has been effective in decreasing the incidence of diarrhea in weaning piglets. However, the overuse of antibiotics as prophylactic or therapeutic agents in animal feed leads to the evolution of drug-…
View article: A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP
A synthetic cationic antimicrobial peptide inhibits inflammatory response and the NLRP3 inflammasome by neutralizing LPS and ATP Open
Antimicrobial peptides (AMPs) are one of the most important defense mechanisms against bacterial infections in insects, plants, non-mammalian vertebrates, and mammals. In the present study, a class of synthetic AMPs was evaluated for anti-…
View article: Considering sex as a biological variable in preclinical research
Considering sex as a biological variable in preclinical research Open
In June 2015, the National Institutes of Health (NIH) released a Guide notice (NOT‐OD‐15–102) that highlighted the expectation of the NIH that the possible role of sex as a biologic variable be factored into research design, analyses, and …