Gao Wei-li
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View article: Upregulation of FLT1 activates the TGF-β1/Smad3 pathway to promote iodide resistance in thyroid cancer
Upregulation of FLT1 activates the TGF-β1/Smad3 pathway to promote iodide resistance in thyroid cancer Open
The upregulation of FLT1 can activate the TGF-β1/Smad3 pathway, downregulate the expression of NIS and enhance the function of thyroid cancer cells.
View article: Downregulation of Rap1GAP Expression Activates the TGF‐<i>β</i>/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells
Downregulation of Rap1GAP Expression Activates the TGF‐<i>β</i>/Smad3 Pathway to Inhibit the Expression of Sodium/Iodine Transporter in Papillary Thyroid Carcinoma Cells Open
Objective . Rap1GAP is considered a tumor suppressor gene, but its regulatory mechanism in papillary thyroid cancer (PTC) has not been clearly elucidated. The aim of this study was to explore whether the regulation between Rap1GAP and sodi…
View article: Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients
Nine Genes Mediate the Therapeutic Effects of Iodine-131 Radiotherapy in Thyroid Carcinoma Patients Open
Background . Thyroid carcinoma (THCA) is one of the most common malignancies of the endocrine system, which is usually treated by surgery combined with iodine-131 (I 131 ) radiotherapy. Aims . This study is aimed at exploring the potential…
View article: The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression
The downregulation of Rap1 GTPase-activating protein is associated with a poor prognosis in colorectal cancer and may impact on tumor progression Open
Rap1 GTPase-activating protein (Rap1GAP) has been reported to serve an important role in various types of cancer by specific stimulation as a negative regulator of Rap1 activity. However, the role of Rap1GAP in colorectal cancer (CRC) has …