Wei Xiang
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View article: Risk factor analysis for growing pains in children: Results of parental survey
Risk factor analysis for growing pains in children: Results of parental survey Open
Objectives: To identify lifestyle-related risk factors for growing pains to advance the clinical prevention and management strategies. Methods: A case–control study was conducted from September 2023 to December 2024, enrolling 290 children…
View article: LCGC: Learning from Consistency Gradient Conflicting for Class-Imbalanced Semi-Supervised Debiasing
LCGC: Learning from Consistency Gradient Conflicting for Class-Imbalanced Semi-Supervised Debiasing Open
Classifiers often learn to be biased corresponding to the class-imbalanced dataset under the semi-supervised learning (SSL) set. While previous work tries to appropriately re-balance the classifiers by subtracting a class-irrelevant image'…
View article: LCGC: Learning from Consistency Gradient Conflicting for Class-Imbalanced Semi-Supervised Debiasing
LCGC: Learning from Consistency Gradient Conflicting for Class-Imbalanced Semi-Supervised Debiasing Open
Classifiers often learn to be biased corresponding to the class-imbalanced dataset, especially under the semi-supervised learning (SSL) set. While previous work tries to appropriately re-balance the classifiers by subtracting a class-irrel…
View article: Prevalence of Brucella in dogs in China: a systematic review and meta-analysis—Epidemiological analysis of canine brucellosis
Prevalence of Brucella in dogs in China: a systematic review and meta-analysis—Epidemiological analysis of canine brucellosis Open
Introduction Brucellosis is a zoonotic disease that affects both dogs and humans. With the increase in dog ownership, the risk of transmission has risen for both adults and children. Methods This study used meta-analysis to comprehensively…
View article: Integration of Immune Cell Signatures and Diagnostic Gene Markers in Pancreatitis: A Comprehensive Study on Therapeutic Targets and Predictive Diagnosis
Integration of Immune Cell Signatures and Diagnostic Gene Markers in Pancreatitis: A Comprehensive Study on Therapeutic Targets and Predictive Diagnosis Open
Pancreatitis is a severe and increasingly prevalent disease that affects the digestive system. Early detection and accurate diagnosis of this condition are crucial for reducing mortality rates and improving patient outcomes. Therefore, the…
View article: Perfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study
Perfluorinated compounds linked to central precocious puberty in girls during COVID-19: an untargeted metabolomics study Open
Background and objective The incidence of central precocious puberty (CPP) in girls increased significantly during the COVID-19 pandemic. This study aimed to explore the impact of perfluorinated endocrine disruptors on CPP through metabolo…
View article: The Synaptic and Circuit Functions of Vitamin D in Neurodevelopment Disorders
The Synaptic and Circuit Functions of Vitamin D in Neurodevelopment Disorders Open
Vitamin D deficiency/insufficiency is a public health issue around the world. According to epidemiological studies, low vitamin D levels have been associated with an increased risk of some neurodevelopmental disorders, including autism spe…
View article: Gut microbiome combined with metabolomics reveals biomarkers and pathways in central precocious puberty
Gut microbiome combined with metabolomics reveals biomarkers and pathways in central precocious puberty Open
Background Central precocious puberty (CPP) is a common disease in prepubertal children and results mainly from disorders in the endocrine system. Emerging evidence has highlighted the involvement of gut microbes in hormone secretion, but …
View article: Clinical and epidemiological investigation of a child with asymptomatic COVID-19 infection following reoccurrence
Clinical and epidemiological investigation of a child with asymptomatic COVID-19 infection following reoccurrence Open
Objective To investigate the case of a child infected with coronavirus disease 2019 (COVID-19) who had subsequent viral reactivation. Methods We retrospectively analyzed the clinical manifestations, epidemiological data, laboratory and ima…
View article: Pediatric Pan-Central Nervous System Tumor Methylome Analyses Reveal Immune-Related LncRNAs
Pediatric Pan-Central Nervous System Tumor Methylome Analyses Reveal Immune-Related LncRNAs Open
Pediatric central nervous system (CNS) tumors are the second most common cancer diagnosis among children. Long noncoding RNAs (lncRNAs) emerge as critical regulators of gene expression, and they play fundamental roles in immune regulation.…
View article: Epidemiological study and health management of an imported incident of COVID–19 asymptomatic cases in Haikou, China
Epidemiological study and health management of an imported incident of COVID–19 asymptomatic cases in Haikou, China Open
Background: To control the imported risks brought by all international arrivals, China Customs has implemented strict closed-loop health management policy called “three checks, three screenings and one transfer”. This study provides epidem…
View article: Predictive modeling of 30-day readmission risk of diabetes patients by logistic regression, artificial neural network, and EasyEnsemble
Predictive modeling of 30-day readmission risk of diabetes patients by logistic regression, artificial neural network, and EasyEnsemble Open
Objective: To determine the most influential data features and to develop machine learning approaches that best predict hospital readmissions among patients with diabetes. Methods: In this retrospective cohort study, we surveyed patient st…
View article: Correlation Analysis between Gut Microbiota and Metabolites in Children with Systemic Lupus Erythematosus
Correlation Analysis between Gut Microbiota and Metabolites in Children with Systemic Lupus Erythematosus Open
Systemic lupus erythematosus (SLE) is an autoimmune-mediated diffuse connective tissue disease characterized by immune inflammation with an unclear aetiology and pathogenesis. This work profiled the intestinal flora and faecal metabolome o…
View article: Untangle the Multi-Facet Functions of Auts2 as an Entry Point to Understand Neurodevelopmental Disorders
Untangle the Multi-Facet Functions of Auts2 as an Entry Point to Understand Neurodevelopmental Disorders Open
Neurodevelopmental disorders are psychiatric diseases that are usually first diagnosed in infancy, childhood and adolescence. Autism spectrum disorder (ASD) is a neurodevelopmental disorder, characterized by core symptoms including impaire…
View article: Epidemiological investigation of a COVID-19 family cluster outbreak transmitted by a 3-month-old infant
Epidemiological investigation of a COVID-19 family cluster outbreak transmitted by a 3-month-old infant Open
Objective To investigate the clinical characteristics, epidemiological characteristics, and transmissibility of coronavirus disease 2019 (COVID-19) in a family cluster outbreak transmitted by a 3-month-old confirmed positive infant. Method…
View article: IFN-I Mediates Dysfunction of Endothelial Progenitor Cells in Atherosclerosis of Systemic Lupus Erythematosus
IFN-I Mediates Dysfunction of Endothelial Progenitor Cells in Atherosclerosis of Systemic Lupus Erythematosus Open
Systemic lupus erythematosus (SLE) is a multi-system autoimmune disease including the cardiovascular system. Atherosclerosis is the most common cardiovascular complication of SLE and a significant risk factor for morbidity and mortality. V…
View article: Diagnosis and treatment experience of COVID-19 in a three-monthold baby
Diagnosis and treatment experience of COVID-19 in a three-monthold baby Open
The three-month-old infant, born in Xiaogan City, Hubei Province , was hospitalized due to
\nfever for 4 hours on January 26, 2020 .The throat swab test was positive for SARS-CoV-2
\nnucleic acid, and the final diagnosis was COVID-19. The …
View article: Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKCδ/ERK Signaling Pathway
Roles of 1,25(OH)2D3 and Vitamin D Receptor in the Pathogenesis of Rheumatoid Arthritis and Systemic Lupus Erythematosus by Regulating the Activation of CD4+ T Cells and the PKCδ/ERK Signaling Pathway Open
Background/Aims: The study aims to elucidate the roles of 1,25(OH)2D3 and vitamin D receptor (VDR) in the pathogenesis of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) by regulating the activation of CD4+ T cells and the…