Weilin Zhang
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View article: Revascularization treatment for posterior circulation ischemic stroke: a systematic review and network meta-analysis
Revascularization treatment for posterior circulation ischemic stroke: a systematic review and network meta-analysis Open
View article: Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene
Machine learning‑based signature for prognosis and drug sensitivity in hepatocellular carcinoma using glycolysis‑related gene Open
Hepatocellular carcinoma (HCC) is one of the most prevalent tumors in the world and poses a considerable threat to global healthcare. The reprogramming of glucose metabolism in tumor cells has demonstrated a notable association with the ge…
View article: Polyethylene microplastics trigger osteosarcoma progression via ITGA5/FAPα/LGMN cancer promoting complex: A novel environmental cancer promoting mechanism
Polyethylene microplastics trigger osteosarcoma progression via ITGA5/FAPα/LGMN cancer promoting complex: A novel environmental cancer promoting mechanism Open
This study seeks to elucidate the molecular mechanisms by which polyethylene microplastics (PE-MPs) facilitate the progression of osteosarcoma through the modulation of the ITGA5/FAPα/LGMN protein complex. Initially, tumor tissues were obt…
View article: Cenozoic paleoecological evolution of NE Tibet: A review of magnetostratigraphically-constrained mammal records
Cenozoic paleoecological evolution of NE Tibet: A review of magnetostratigraphically-constrained mammal records Open
View article: Design and Evaluation of Hybrid Drivetrain Damper Considering the Influence of Engine Misfire on Torsional Shock
Design and Evaluation of Hybrid Drivetrain Damper Considering the Influence of Engine Misfire on Torsional Shock Open
Engine misfire is an accidental failure mode in internal combustion vehicles that can lead to the malfunction of power transmission system components. However, previous studies on engine misfire have generally focused on the engine rather …
View article: Mid-Pleistocene aridity and landscape shifts promoted Palearctic hominin dispersals
Mid-Pleistocene aridity and landscape shifts promoted Palearctic hominin dispersals Open
Population expansions and contractions out of and into Africa since the early Pleistocene have influenced the course of human evolution. While local- and regional-scale investigations have provided insights into the drivers of Eurasian hom…
View article: Surface Regulation via Carboxylate Polymer for Efficient and Stable CsPbI<sub>2</sub>Br Perovskite Solar Cells
Surface Regulation via Carboxylate Polymer for Efficient and Stable CsPbI<sub>2</sub>Br Perovskite Solar Cells Open
CsPbI 2 Br perovskite solar cell (PSC) is a promising candidate for high‐efficiency single‐junction and tandem solar cells. However, due to the numerous surface defects of the CsPbI 2 Br film and the mismatch of energy levels at the CsPbI …
View article: A New Nonaqueous Flow Battery with Extended Cycling
A New Nonaqueous Flow Battery with Extended Cycling Open
Nonaqueous flow batteries hold promise given their high cell voltage and energy density, but their performance is often plagued by the crossover of redox compounds. In this study, we used permselective lithium superionic conducting (LiSICO…
View article: Conductive material Gel@Ti3C2/MT regulates the PI3K/AKT/HIF-1α/TIMP1 pathway affecting MT1 for inhibiting osteosarcoma
Conductive material Gel@Ti3C2/MT regulates the PI3K/AKT/HIF-1α/TIMP1 pathway affecting MT1 for inhibiting osteosarcoma Open
Osteosarcoma is the most common primary malignant tumor of bone, and there are many drawbacks in current treatment methods, and it is necessary to explore new treatment methods. In this study, we show that TIMP1 may play an important role …
View article: Dilated Spectral–Spatial Gaussian Transformer Net for Hyperspectral Image Classification
Dilated Spectral–Spatial Gaussian Transformer Net for Hyperspectral Image Classification Open
In recent years, deep learning-based classification methods for hyperspectral images (HSIs) have gained widespread popularity in fields such as agriculture, environmental monitoring, and geological exploration. This is owing to their abili…
View article: Cretaceous magnetostratigraphy of the southern Simao Basin, SE Tibetan Plateau and its paleogeographical significance (Supplementary data)
Cretaceous magnetostratigraphy of the southern Simao Basin, SE Tibetan Plateau and its paleogeographical significance (Supplementary data) Open
The Simao Basin has deposited thick continuous Cretaceous sedimentary sequence that contains abundant information about the regional tectonic, pre-Indian monsoon paleoclimatic condition and resource effect prior to the India-Asia collision…
View article: Middle Pleistocene Weakening of the Indian Summer Monsoon Driven by Global Cooling
Middle Pleistocene Weakening of the Indian Summer Monsoon Driven by Global Cooling Open
View article: Magnetic Proxy of Eurasian Loess Revealing Enhanced Physical Erosion Since the Mid‐Pleistocene Transition
Magnetic Proxy of Eurasian Loess Revealing Enhanced Physical Erosion Since the Mid‐Pleistocene Transition Open
Eolian loess deposits contain valuable information about past climate changes and erosion history in dust source regions. In contrast to the extensive investigations of paleoclimatic implications of Eurasian loess, continental erosion info…
View article: Exploration of Net Property Income in Different Regions
Exploration of Net Property Income in Different Regions Open
Nowadays, people's life satisfaction largely depends on their net property income, and as the quality of life improves, people begin to focus on the management of their existing assets and formulate investment strategies. This paper uses S…
View article: Global cooling controls Paleogene (54-26 Ma) paleolake hydrological evolution and regional chemical weathering processes in the Qaidam Basin, NE Tibet
Global cooling controls Paleogene (54-26 Ma) paleolake hydrological evolution and regional chemical weathering processes in the Qaidam Basin, NE Tibet Open
The thick and continuous lacustrine-fluvial sediments in the Qaidam Basin (paleo-Qaidam Lake), NE Tibetan Plateau, serve as excellent archives to reconstruct the Asian inland climate evolution history and explore the driven factors involvi…
View article: A new biologic paleoaltimetry applied to the paleo-Qaidam Lake sedimentary sequences indicating Late Miocene rapid uplift of northern Tibet Plateau
A new biologic paleoaltimetry applied to the paleo-Qaidam Lake sedimentary sequences indicating Late Miocene rapid uplift of northern Tibet Plateau Open
The Tibet Plateau is the world’s highest inhabited terrain, with an area >2.5×106 km2 and an average elevation >4000 m asl. Its uplift has been regarded as the main factor driving the evolution of the Asian monsoon regime and al…
View article: Coevolution-based prediction of key allosteric residues for protein function regulation
Coevolution-based prediction of key allosteric residues for protein function regulation Open
Allostery is fundamental to many biological processes. Due to the distant regulation nature, how allosteric mutations, modifications, and effector binding impact protein function is difficult to forecast. In protein engineering, remote mut…
View article: Mid-Pleistocene aridity and landscape shifts drove Palearctic hominin dispersalsy and landscape shifts drove Palearctic hominin dispersalsled Item
Mid-Pleistocene aridity and landscape shifts drove Palearctic hominin dispersalsy and landscape shifts drove Palearctic hominin dispersalsled Item Open
Carbon isotope records of soil organic matter and total carbonate of eolian sediments in Tajikistan and Tarim Basin.
View article: Lithogenic susceptibility records of Eurasian loess
Lithogenic susceptibility records of Eurasian loess Open
Lithogenic susceptibility records of Eurasian loess
View article: Mineralogical and magnetic records of GZ loess
Mineralogical and magnetic records of GZ loess Open
Mineralogical and magnetic records of GZ loess
View article: Mineralogical and magnetic records of GZ loess
Mineralogical and magnetic records of GZ loess Open
Mineralogical and magnetic records of GZ loess
View article: Association between anticholinergic medication uses and the risk of pneumonia in elderly adults: a meta-analysis and systematic review
Association between anticholinergic medication uses and the risk of pneumonia in elderly adults: a meta-analysis and systematic review Open
To conduct a meta-analysis and systematic review on the association between anticholinergic medication uses and the risk of pneumonia in elderly adults. Medical databases were searched included PubMed, Web of Science, EBSCO and Google Scho…
View article: Late Paleogene to Early Neogene Leaf Fossils Imply a High Paleoelevation of the Nangqian Basin, Eastern Tibetan Plateau
Late Paleogene to Early Neogene Leaf Fossils Imply a High Paleoelevation of the Nangqian Basin, Eastern Tibetan Plateau Open
View article: Author response: Coevolution-based prediction of key allosteric residues for protein function regulation
Author response: Coevolution-based prediction of key allosteric residues for protein function regulation Open
View article: Research on the Safety of Aquatic Products Transportation under the Background of the New Crown Epidemic
Research on the Safety of Aquatic Products Transportation under the Background of the New Crown Epidemic Open
Due to the impact of the new coronavirus, the transportation and sales links of many aquaculture industries have experienced serious obstacles. Not only the transportation between provinces is affected by changes in the epidemic situation,…
View article: Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK
Silybin A enhances circadian clock by targeting CRY1 and disrupting its interaction with CLOCK Open
Circadian clock governs a large array of physiological and metabolic functions. The amplitude decline of circadian rhythm is associated with various chronic diseases. However, few clock enhancing-molecules are known. CRY1 is one of the mai…
View article: FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia
FUNDC1-mediated mitophagy and HIF1α activation drives pulmonary hypertension during hypoxia Open
Hypoxic pulmonary hypertension (PH) is a progressive disease characterized by hyper-proliferation of pulmonary vascular cells including pulmonary artery smooth muscle cells (PASMCs) and can lead to right heart failure and early death. Sele…
View article: A novel compound heterozygous SPG7 variant is associated with progressive spastic ataxia and persecutory delusions found in Chinese patients: two case reports
A novel compound heterozygous SPG7 variant is associated with progressive spastic ataxia and persecutory delusions found in Chinese patients: two case reports Open
View article: Anisotropy of Magnetic Susceptibility Reveals Late Miocene Tectonic Activity in the Western Qaidam Basin
Anisotropy of Magnetic Susceptibility Reveals Late Miocene Tectonic Activity in the Western Qaidam Basin Open
The western Qaidam Basin on the northeastern Tibetan Plateau located at the intersection between the Altyn Tagh Fault and the Kunlun Fault/Qimen Tagh Fault holds significant potential to reveal the tectonic process of these two faults as w…
View article: Mitophagy‐regulated mitochondrial health strongly protects the heart against cardiac dysfunction after acute myocardial infarction
Mitophagy‐regulated mitochondrial health strongly protects the heart against cardiac dysfunction after acute myocardial infarction Open
Autophagy including mitophagy serves as an important regulatory mechanism in the heart to maintain the cellular homeostasis and to protect against heart damages caused by myocardial infarction (MI). The current study aims to dissect roles …