Wei‐Ling Chang
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View article: Solving the Two-Stage Design Interest Paradox Between Chinese EPC Project Owners and General Contractors: A Case Study
Solving the Two-Stage Design Interest Paradox Between Chinese EPC Project Owners and General Contractors: A Case Study Open
In recent years, China has vigorously promoted the EPC mode in the construction industry. However, under the weak trust environment of China’s construction industry, both owners and general contractors are involved in the design stage of E…
View article: Double-sided niche regulation in skin stem cell and cancer: mechanisms and clinical applications
Double-sided niche regulation in skin stem cell and cancer: mechanisms and clinical applications Open
The niche microenvironment plays a crucial role in regulating the fate of normal skin stem cells (SSCs) and cancer stem cells (CSCs). Therapeutically targeting the CSC niche holds promise as an effective strategy; however, the dual effects…
View article: Power Relationships among Local Officials, Literati, and Society: An Analysis of Yuan Dynasty Inscriptions from Puyang, Fujian
Power Relationships among Local Officials, Literati, and Society: An Analysis of Yuan Dynasty Inscriptions from Puyang, Fujian Open
This article uses inscriptions related to public construction projects as its main source in order to explore the relationship among local government, local literati, and local society in the Yuan dynasty, using the example of Puyang, Fuji…
View article: Process optimization and mechanical properties analysis of Inconel 718/stainless steel 316 L multi-material via direct energy deposition
Process optimization and mechanical properties analysis of Inconel 718/stainless steel 316 L multi-material via direct energy deposition Open
Additive manufacturing (AM), also known as 3D printing, is a recent innovation in manufacturing, employing additive techniques rather than traditional subtractive methods. This study focuses on Directed Energy Deposition (DED), utilizing a…
View article: Process Optimization and Mechanical Properties Analysis of Inconel 718/Stainless Steel 316L Multi-material via Direct Energy Deposition
Process Optimization and Mechanical Properties Analysis of Inconel 718/Stainless Steel 316L Multi-material via Direct Energy Deposition Open
Additive manufacturing (AM), also known as 3D printing, is a recent innovation in manufacturing, employing additive techniques rather than traditional subtractive methods. This study focuses on Directed Energy Deposition (DED), utilizing a…
View article: The Role of Oxidative Stress in Vitiligo: An Update on Its Pathogenesis and Therapeutic Implications
The Role of Oxidative Stress in Vitiligo: An Update on Its Pathogenesis and Therapeutic Implications Open
Vitiligo is an autoimmune skin disorder caused by dysfunctional pigment-producing melanocytes which are attacked by immune cells. Oxidative stress is considered to play a crucial role in activating consequent autoimmune responses related t…
View article: Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention
Vitiligo: An Autoimmune Skin Disease and its Immunomodulatory Therapeutic Intervention Open
Vitiligo is a chronic autoimmune depigmenting skin disorder characterized by patches of the skin losing functional melanocytes. Multiple combinatorial factors are involved in disease development, among which immune T cells play a prominent…
View article: AB063. P-34. A multicenter, phase 1b/2 study of varlitinib plus gemcitabine and cisplatin (gem/cis) for treatment naïve advanced or metastatic biliary tract cancer (BTC)
AB063. P-34. A multicenter, phase 1b/2 study of varlitinib plus gemcitabine and cisplatin (gem/cis) for treatment naïve advanced or metastatic biliary tract cancer (BTC) Open
BACKGROUND: Biliary tract cancer (BTC) is a rapidly progressing cancer with limited response to chemotherapy. First line therapy (gem/cis) was defined in the ABC-02 study (Valle et al.), where a 26% response was seen. HER family receptors …
View article: AB062. P-33. Efficacy and safety of varlitinib, a reversible pan-HER tyrosine kinase inhibitor, in combination with platinum-based regimens in biliary tract cancers: a pooled analysis from three phase 1 studies
AB062. P-33. Efficacy and safety of varlitinib, a reversible pan-HER tyrosine kinase inhibitor, in combination with platinum-based regimens in biliary tract cancers: a pooled analysis from three phase 1 studies Open
BACKGROUND: Varlitinib is a nanomolar inhibitor of EGFR, HER2, and HER4 and has shown potent anti-tumor activity as monotherapy in preclinical BTC models. During phase (Ph) 1 development, significant tumor shrinkage was observed in biliary…
View article: Retraction of “Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators”
Retraction of “Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators” Open
ADVERTISEMENT RETURN TO ISSUEPREVRetractionNEXTORIGINAL ARTICLEThis notice is a retraction.Retraction of "Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators"Jih-Hwa GuhJih-Hwa GuhMore by Jih-Hwa Guh, Wei-Ling …
View article: Recurrent Advanced Lower Extremity Lymphedema Following Initial Successful Vascularized Lymph Node Transfer: A Clinical and Histopathological Analysis
Recurrent Advanced Lower Extremity Lymphedema Following Initial Successful Vascularized Lymph Node Transfer: A Clinical and Histopathological Analysis Open
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