Weinan Deng
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View article: CASP3-GSDME-mediated trophoblast pyroptosis contributes to systemic inflammation
CASP3-GSDME-mediated trophoblast pyroptosis contributes to systemic inflammation Open
Early-onset preeclampsia (EOPE) is associated with excessive apoptosis and inflammation, but the mechanistic link between these processes remains enigma. Here, we report elevated circulating pro-apoptotic proteins in EOPE patients at early…
View article: Dingkun pill alleviates metabolic abnormalities in polycystic ovary syndrome through brown adipose tissue activation
Dingkun pill alleviates metabolic abnormalities in polycystic ovary syndrome through brown adipose tissue activation Open
View article: Dingkun Pill Alleviates Metabolic Abnormalities in Polycystic Ovary Syndrome Through Brown Adipose Tissue Activation
Dingkun Pill Alleviates Metabolic Abnormalities in Polycystic Ovary Syndrome Through Brown Adipose Tissue Activation Open
View article: Cultivation through Management in Colleges and Universities in the New Era: Connotation, Characteristics and Functions
Cultivation through Management in Colleges and Universities in the New Era: Connotation, Characteristics and Functions Open
The cultivation with management work in colleges and universities is the basis and guarantee for the smooth development of other education work, is an important part of the education work in colleges and universities in the new era, and pl…
View article: The association of serum total bile acid with new-onset hypertension during pregnancy
The association of serum total bile acid with new-onset hypertension during pregnancy Open
View article: TNFα/TNFR1 signal induces excessive senescence of decidua stromal cells in recurrent pregnancy loss
TNFα/TNFR1 signal induces excessive senescence of decidua stromal cells in recurrent pregnancy loss Open
Defects in decidual response are associated with adverse pregnancy outcomes which includes recurrent pregnancy loss (RPL). It is reported that cellular senescence happens during decidualization and pro-senescent decidual response in the lu…
View article: The association of serum total bile acid with new-onset hypertension during pregnancy
The association of serum total bile acid with new-onset hypertension during pregnancy Open
Background: There has been considerable interest in the interrelationship between the liver and hypertension. The relationship between serum total bile acid (TBA) and hypertension has been reported. Moreover, intrahepatic cholestasis of pr…
View article: Association between the second-stage duration of labor and perinatal outcomes in women with a prior cesarean delivery
Association between the second-stage duration of labor and perinatal outcomes in women with a prior cesarean delivery Open
View article: Dynamic Monitoring of Desertification in Ningdong Based on Landsat Images and Machine Learning
Dynamic Monitoring of Desertification in Ningdong Based on Landsat Images and Machine Learning Open
The ecological stability of mining areas in Northwest China has been threatened by desertification for a long time. Remote sensing information combined with machine learning algorithms can effectively monitor and evaluate desertification. …
View article: Integrated Metabolomic and Lipidomic Analysis in the Placenta of Preeclampsia
Integrated Metabolomic and Lipidomic Analysis in the Placenta of Preeclampsia Open
Preeclampsia is one of the most common severe pregnancy complications in obstetrics, which is considered a placental source disease. However, the mechanisms underlying preeclampsia remain largely unknown. In this study, UPLC-MS/MS-based me…
View article: Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion
Single‐cell transcriptome analysis reveals defective decidua stromal niche attributes to recurrent spontaneous abortion Open
Objectives Successful pregnancy involves the homeostasis between maternal decidua and fetoplacental units, whose disruption contributes to compromised pregnancy outcomes, including recurrent spontaneous abortion (RSA). The role of cell het…
View article: Application of the amniotic fluid metabolome to the study of fetal malformations, using Down syndrome as a specific model
Application of the amniotic fluid metabolome to the study of fetal malformations, using Down syndrome as a specific model Open
Although monitoring and diagnosis of fetal diseases in utero remains a challenge, metabolomics may provide an additional tool to study the etiology and pathophysiology of fetal diseases at a functional level. In order to explore specific m…