Weipeng Shao
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View article: Deep learning radiomics model of epicardial adipose tissue for predicting postoperative atrial fibrillation after lung lobectomy in lung cancer patients
Deep learning radiomics model of epicardial adipose tissue for predicting postoperative atrial fibrillation after lung lobectomy in lung cancer patients Open
Objective To develop and validate a deep learning (DL) radiomics model based on epicardial adipose tissue (EAT) for identifying high-risk lung cancer patients with postoperative atrial fibrillation after lung lobectomy. Methods A total of …
View article: Ultrasound imaging of the thyroid snowstorm sign in metastatic lung adenocarcinoma
Ultrasound imaging of the thyroid snowstorm sign in metastatic lung adenocarcinoma Open
View article: The Role of Circulating Tumor Cell as a Promising Biomarker in the Evaluation of Pulmonary Nodules: A Prospective Study
The Role of Circulating Tumor Cell as a Promising Biomarker in the Evaluation of Pulmonary Nodules: A Prospective Study Open
CTC count can be used in identifying malignant PNs. The diagnostic efficacy can be improved if combined with CT imaging characteristics. Further CNV analysis might help differential diagnosis. Greater CTC count might suggest more aggressiv…
View article: Effects of different degrees of anthracosis on pleural structure: A preliminary exploratory study
Effects of different degrees of anthracosis on pleural structure: A preliminary exploratory study Open
The current study demonstrated that the proportion of PA is negatively correlated with pleural thickness and positively correlated with the number of SLVs, cross-sectional area of SLVs, length of SLVs, and SLVs density. This study provides…
View article: Pathological responses of primary tumor and lymph nodes in non-small cell lung cancer after neoadjuvant chemoimmunotherapy: a retrospective real-world study
Pathological responses of primary tumor and lymph nodes in non-small cell lung cancer after neoadjuvant chemoimmunotherapy: a retrospective real-world study Open
In this real-world study, the combination of tumor and LNs responses was significantly associated with prognosis, and we demonstrated that ypTMPR(+)/ypN(0) group had a better prognosis, followed by ypTMPR(-)/ypN(0), ypTMPR(+)/ypN(0), and y…
View article: Neoadjuvant targeted therapy versus targeted combined with chemotherapy for resectable EGFR-mutant non–small cell lung cancer: a retrospective controlled real-world study
Neoadjuvant targeted therapy versus targeted combined with chemotherapy for resectable EGFR-mutant non–small cell lung cancer: a retrospective controlled real-world study Open
Background This study aimed to assess the role and effect of neoadjuvant targeted therapy (TT) versus targeted combined with chemotherapy (TC) for resectable EGFR-mutant non–small cell lung cancer (NSCLC). Methods Between March 2021 and Ju…
View article: Effects of Different Degrees of Anthracosis on Pleural Structure: A Preliminary Exploratory Study
Effects of Different Degrees of Anthracosis on Pleural Structure: A Preliminary Exploratory Study Open
View article: CTCs Detection and Whole-exome Sequencing Might Be Used to Differentiate Benign and Malignant Pulmonary Nodules.
CTCs Detection and Whole-exome Sequencing Might Be Used to Differentiate Benign and Malignant Pulmonary Nodules. Open
CTCs play an ancillary role in the diagnosis of pulmonary nodules. TP53 mutations in CTCs might be used to identify benign and malignant pulmonary nodules.
View article: Primary lung cancer in children and adolescents: Analysis of a surveillance, epidemiology, and end results database
Primary lung cancer in children and adolescents: Analysis of a surveillance, epidemiology, and end results database Open
Background The incidence of primary lung cancer (LC) in children and adolescence was rare. We analyzed data from a SEER database to better define the incidence, clinical characters, pathology, treatment, and outcomes of rare primary malign…
View article: The Predictive Value of Stair Climbing Test on Postoperative Complications in Lung Cancer Patients with Limited Pulmonary Function
The Predictive Value of Stair Climbing Test on Postoperative Complications in Lung Cancer Patients with Limited Pulmonary Function Open
The SCT could be used as a preoperative screening method for lung cancer patients with limited pulmonary function. For those patients who could only climb less than 6 floors or had ∆HR >30 bpm in the test, sublobar resection should be sele…
View article: The role of peripheral inflammatory cells in predicting radiation pneumonitis
The role of peripheral inflammatory cells in predicting radiation pneumonitis Open
Background: Radiation pneumonitis (RP) is a common complication of thoracic radiation which affects patients' ability to breathe, limits the deliverable intensity of radiotherapy and impairs clinical outcomes, indicating the need for timel…
View article: The value of pulmonary nodule diameter and consolidation/tumor rate in the prediction of lymph node metastasis in early-stage (cT1N0M0) lung adenocarcinoma
The value of pulmonary nodule diameter and consolidation/tumor rate in the prediction of lymph node metastasis in early-stage (cT1N0M0) lung adenocarcinoma Open
VPI, DP, DM, CTR, and total dissected LNs number categories were independent factors for LNs metastasis. If DM ≥11.81 cm, or CTR ≥79.50%, or VPI systemic lymphadenectomy was recommended. We suggested 14 LNs as the cut point for the evaluat…
View article: Clinicopathological characteristics of peripheral clinical stage IA lung adenocarcinoma with high Ki-67 expression
Clinicopathological characteristics of peripheral clinical stage IA lung adenocarcinoma with high Ki-67 expression Open
Male sex, CEA positivity, notch positivity, vascular convergence, and CTR were significantly associated with high Ki-67 expression in patients with peripheral clinical stage IA LUAD. These findings could be used to assist clinical decision…
View article: The rate of miR-146a rs2910164 mutations in patients with lung cancer: a meta-analytic review
The rate of miR-146a rs2910164 mutations in patients with lung cancer: a meta-analytic review Open
In conclusion, we can find that the mutation rate of the lung cancer group is higher than the normal people. In the lung cancer group, we can find that the rate of mutation is highest in Italians and lowest in Indians, both in genotypes an…
View article: Predictive value of radiological features on spread through air space in stage cIA lung adenocarcinoma
Predictive value of radiological features on spread through air space in stage cIA lung adenocarcinoma Open
STAS-positive LUAD was associated with air bronchogram, maximum tumor diameter, maximum solid component diameter and CTR. These radiological features could predict STAS with excellent sensitivity but inferior specificity.
View article: Pulmonary mucormycosis: a case of pulmonary arterial hypertension, Westermark sign, and bronchopleural fistula
Pulmonary mucormycosis: a case of pulmonary arterial hypertension, Westermark sign, and bronchopleural fistula Open
We herein describe a patient with pulmonary mucormycosis and acute myelogenous leukemia. Computed tomography showed a widened pulmonary artery, a bronchopleural fistula, and the Westermark sign. Despite worsening hemoptysis, the operation …
View article: Charlson comorbidity index as a predictor of short-term outcomes after pulmonary resection
Charlson comorbidity index as a predictor of short-term outcomes after pulmonary resection Open
The main finding of the present study was that CCI >3 was associated with a poor short-term outcome. For patients with CCI >3, it was suggested that the experienced surgical team should perform pulmonary resection in the shortest time and …
View article: Detection of SHOX2 DNA methylation by methylation-specific PCR in non-small cell lung cancer
Detection of SHOX2 DNA methylation by methylation-specific PCR in non-small cell lung cancer Open
These results suggested that SHOX2 gene methylation was closely associated with lung carcinogenesis. Thus, SHOX2 methylation could be used as a potential marker to help NSCLC detection. MSP might be used as a cost-effective method a…
View article: Paeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis
Paeonol Inhibits Cell Proliferation, Migration and Invasion and Induces Apoptosis in Hepatocellular Carcinoma by Regulating miR-21-5p/KLF6 Axis Open
Miaoguo Cai,1,* Wei Shao,1,* Huijun Yu,2 Ye Hong,1 Lili Shi3 1Department of Medical Oncology, Luqiao Branch of Taizhou Hospital, Taizhou City, Zhejiang Province, People’s Republic of China; 2Department of Pediatric, Luqiao Branch of Taizho…
View article: Characteristics of pulmonary mucormycosis and the experiences of surgical resection
Characteristics of pulmonary mucormycosis and the experiences of surgical resection Open
PM is a rare but fatal infection. Due to chest adhesion and vascular invasion, the proportion of massive bleeding and long operation time has increased sharply.
View article: Impact of interstitial lung disease on postoperative morbidity and 90-day mortality after pulmonary resection
Impact of interstitial lung disease on postoperative morbidity and 90-day mortality after pulmonary resection Open
Patients with ILD had a higher incidence of postoperative morbidity and 90-day mortality. ASA classification was an important influencing factor for AE-ILD. Based on the obvious postoperative morbidity and mortality, special attention and …
View article: Knockdown of actin-like 8 inhibits cell proliferation by regulating FOXM1, STMN1, PLK1, and BIRC5 in lung adenocarcinoma A549 cells
Knockdown of actin-like 8 inhibits cell proliferation by regulating FOXM1, STMN1, PLK1, and BIRC5 in lung adenocarcinoma A549 cells Open
Background: Actin-like protein 8 (ACTL8) is a member of the CTA family, and it is expressed in various types of cancer, including glioblastoma and breast cancer. However, whether ACTL8 is involved in the development of lung adenocarcinoma…
View article: Knockdown of actin-like 8 inhibits cell proliferation by regulating FOXM1, STMN1, PLK1, and BIRC5 in lung adenocarcinoma A549 cells
Knockdown of actin-like 8 inhibits cell proliferation by regulating FOXM1, STMN1, PLK1, and BIRC5 in lung adenocarcinoma A549 cells Open
In summary, these results suggest that a knockdown of ACTL8 inhibits cell proliferation in human LUAD A549 cells by regulating FOXM1, STMN1, PLK1, and BIRC5.
View article: Community-acquired versus hospital-acquired acute kidney injury in patients with acute exacerbation of COPD requiring hospitalization in China
Community-acquired versus hospital-acquired acute kidney injury in patients with acute exacerbation of COPD requiring hospitalization in China Open
Chang-chun Cao,1,* Da-wei Chen,2,* Jing Li,2 Meng-qing Ma,2 Yu-bao Chen,3 Yi-zhi Cao,4 Xi Hua,2 Wei Shao,1 Xin Wan2 1Department of Nephrology, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, China; 2Department of Nephro…
View article: [Recent Advances and Future Strategies for Small Cell Lung Cancer].
[Recent Advances and Future Strategies for Small Cell Lung Cancer]. Open
Small cell lung cancer (SCLC) is a malignant tumor with a very high mortality rate. The current standard of care includes surgery, chemotherapy and radiotherapy. The clinical benefit of therapies was disappointing. Recently, many clinical …