Explanipedia

Comparative Effectiveness of Exercise and Protein-Based Interventions on Muscle Strength, Mass, and Function in Sarcopenia: A Systematic Review and Network Meta-Analysis Open

Ruixiang Yan, Shiqi Jia, Di Lu, Wenfeng Song, Weiqi Zhang , et al. · 2025

High-certainty evidence supports RBT + Nu as the most effective intervention for improving muscle strength, muscle mass, and physical function in individuals with sarcopenia. We recommend combining RBT with protein and amino acid supplemen…

Liver–Microbiome Crosstalk Mediates the Protective Effects of Artemisinin in <i>Clostridium perfringens</i> Models Open

Haodong Han, Youhao Li, Lili Wang, Zi‐Bing Jin, Wei Zhou , et al. · 2025

Clostridium perfringens is a multi‐host opportunistic pathogen whose plasmid‐encoded toxins cause gas gangrene, necrotic enteritis and enterotoxemia, resulting in substantial economic losses in animal husbandry. In light of antibiotic bans…

Scutellarin attenuates hypoxia-induced retinal neovascularization through bidirectional modulation of the VEGF/Ang/Tie2 pathway Open

Shan Ding, Wei Wang, Chunmeng Liu, Weiqi Zhang, Jie Wang , et al. · 2025

Introduction Scutellarin (SCU), a flavonoid with established pharmacological activity, exhibits anti-angiogenic and vascular-stabilizing effects in ischemic ocular diseases. Methods This study investigated its bidirectional modulation of t…

SFT Doesn't Always Hurt General Capabilities: Revisiting Domain-Specific Fine-Tuning in LLMs Open

Jiacheng Lin, Ziqi Wang, Kun Qian, Tian Wang, Arvind Srinivasan , et al. · 2025

Supervised Fine-Tuning (SFT) on domain-specific datasets is a common approach to adapt Large Language Models (LLMs) to specialized tasks but is often believed to degrade their general capabilities. In this work, we revisit this trade-off a…

GlyT1 inhibition by ALX-5407 attenuates allograft rejection through suppression of Th1 cell differentiation Open

Xiaohan Zhang, Weiqi Zhang, Jianghao Wei, Shuai Jin, Zhen Wang , et al. · 2025

Objective Transplant rejection driven by Th1 cell-mediated immune responses remains a critical challenge. This study aimed to investigate the role of glycine transporter 1 (GlyT1/SLC6A9) in Th1 differentiation and evaluate the therapeutic …

Pt Nanoparticles Supported on Mesoporous Hollow TiO2@C Sphere Composite as Efficient Methanol Oxidation Reaction Electrocatalysts Open

Yuan Chen, Huiyuan Liu, Qiang Ma, Zhuo Li, Mengyue Lu , et al. · 2025

The large-scale implementation of direct methanol fuel cells (DMFCs) is significantly impeded by sluggish methanol oxidation reaction (MOR) kinetics, degradation of Pt electrocatalysts, and significant carbon support corrosion in commercia…

Improving Performance of a Passive Direct Methanol Fuel Cell by Hydrophobic Treatment for Cathode Current Collector Open

Xiaozhong Shen, Wei‐Bin Yu, Zihao Zhang, Lu Lu, Weiqi Zhang , et al. · 2025

This study employs hydrophobic modification of the current collector to optimize cathode water management and enhance the performance of passive DMFCs. The surface of the cathode current collector was hydrophobized by polytetrafluoroethyle…

Green's function and volume noncollapsing estimates for the Kähler-Ricci flow Open

Weiqi Zhang, Yashan Zhang · 2025

We prove a local volume noncollapsing property for the long-time Kähler-Ricci flow on a minimal Kähler manifold, improving previous results of Guo-Phong-Song-Sturm, Guedj-Tô and Vu. Similar result is also proved for a twisted Kähler-Ricci …

A Semantic Behavioral Sequence-Based Approach to Trajectory Privacy Protection Open

Ji Xi, Weiqi Zhang, Zhengwang Xia, Li Zhao, Huawei Tao · 2025

Trajectory data contain numerous sensitive attributes. Unauthorized disclosure of precise user trajectory information generates persistent privacy and security concerns that significantly impact daily life. Most existing trajectory privacy…

Differential accumulation characteristics and production of coalbed methane/coal-rock gas: A case study of the No. 8 coal seam of the Carboniferous Benxi Formation in the Daji block, Ordos Basin, NW China Open

Lihong Zhou, Yong Li, Rong Ding, Xianyue Xiong, Wei Hou , et al. · 2025

A framework of biomarkers for adipose tissue aging: a consensus statement by the Aging Biomarker Consortium Open

Jinhua Yu, Yankang Zhang, Ting Zhang, Yan Bi, Yan Chen , et al. · 2025

Adipose tissue serves as a crucial energy storage and metabolic organ in the human body. With the surging of elderly population in China comes significant challenges in preventing and managing age-associated diseases, while adipose tissue …

A framework of biomarkers for visual system aging: a consensus statement by the Aging Biomarker Consortium Open

Chao Ma, Baoyou Geng, Yangqing Zhang, Shan Li, Ruiyang Li , et al. · 2025

The visual system is essential for human perception, converting light signals into electrical impulses and transmitting them to the brain to process environmental information. As individuals age, their physiological functions gradually dec…

OP0189 SAFETY AND EFFICACY OF INEBILIZUMAB IN IgG4-RELATED DISEASE ACROSS VARIOUS PARTICIPANT DEMOGRAPHICS: SUBGROUP ANALYSIS FROM THE MITIGATE STUDY Open

John H. Stone, Emma Culver, Arezou Khosroshahi, Weiqi Zhang, Kazuichi Okazaki , et al. · 2025

Mean Absolute Deviation for Hyperexponential and Hypoexponential Distributions Open

Weiqi Zhang, Z.J. Wang, Eugene Pinsky · 2025

Hyperexponential and Hypoexponential distributions are derived from mixtures and convolutions of independent exponential random variables, respectively, and have a wide range of applications in telecommunications, quantitative finance, and…

Correction to: Enhancing cyber defense strategies with discrete multi-dimensional Z-numbers: a multi-attribute decision-making approach Open

Aiting Yao, Chen Huang, Weiqi Zhang, Chengzu Dong, Meiqu Lu , et al. · 2025

Credit rating and stock return comovement Open

Jianfeng Shen, Huiping Zhang, Weiqi Zhang · 2025

Airflow: A double-edged sword in shaping white tea quality Open

Jinyuan Wang, David C. Lin, Jiao Feng, Shuping Ye, W. H. Tian , et al. · 2025

Enhancing cyber defense strategies with discrete multi-dimensional Z-numbers: a multi-attribute decision-making approach Open

Aiting Yao, Chen Huang, Weiqi Zhang, Chengzu Dong, Meiqu Lu , et al. · 2025

With the rapid advancement of intelligent technologies and network environments, the efficient and accurate handling of uncertain decision-making information has become an urgent challenge. Traditional methods often struggle to process com…

Author Correction: A single-cell transcriptomic landscape of primate arterial aging Open

Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song , et al. · 2025

The risk factors for low back pain following oblique lateral interbody fusion: focus on sarcopenia Open

Dazhuang Miao, Mengke Fan, Weiqi Zhang, Xiaowei Ma, Hui Wang , et al. · 2025

Author Correction: SGF29 nuclear condensates reinforce cellular aging Open

Kaowen Yan, Qianzhao Ji, Dongxin Zhao, Mingheng Li, Xiaoyan Sun , et al. · 2025

Speech Enhancement Algorithm Based on Microphone Array and Multi-Channel Parallel GRU-CNN Network Open

Ji Xi, Zhe Xu, Weiqi Zhang, Yue Xie, Li Zhao · 2025

This paper presents an improved speech enhancement algorithm based on microphone arrays to improve speech enhancement performance in complex settings. The algorithm’s model consists of two key components: the feature extraction module and …

Protocols for the application of human embryonic stem cell-derived neurons for aging modeling and gene manipulation Open

Hui Zhang, Shuhui Sun, Juan Carlos Izpisúa Belmonte, Guang‐Hui Liu, Si Wang , et al. · 2025

In vitro models of neuronal aging and gene manipulation in human neurons (hNeurons) are valuable tools for investigating human brain aging and diseases. Here, we present a protocol for applying human embryonic stem cell (hESC)-derived neur…

A biomarker framework for auditory system aging: the Aging Biomarker Consortium consensus statement Open

Xiaolong Fu, Si Wang, Yunhao Wu, Yu Sun, Wenwen Liu , et al. · 2025

Hearing is one of the most vital sensory functions in human beings and a crucial means of perceiving and acquiring information from the natural environment. The advancement of human society is closely linked to the development of language,…

A single-cell transcriptomic atlas of exercise-induced anti–inflammatory and geroprotective effects across the body Open

Shuhui Sun, Shuai Ma, Yusheng Cai, Si Wang, Jie Ren , et al. · 2025

Injectable iodine-containing peptide hydrogel for treatment of MRSA infection Open

Shengdong Zhang, Haiyan Liu, Weiqi Zhang, Yinghao Ding, Zhang Sheng-yi , et al. · 2025

UDA-seq: universal droplet microfluidics-based combinatorial indexing for massive-scale multimodal single-cell sequencing Open

Yun Li, Zheng Huang, Lubin Xu, Yanling Fan, J. L. Ping , et al. · 2025

Impact of Gas Diffusion Layer with a Gradient Pore Size Distribution on Liquid Water Transport in Proton Exchange Membrane Fuel Cell Open

Tianen Wu, Qian Song, Huiyuan Liu, Weiqi Zhang, Qian Xu , et al. · 2025

Bank branch closure and entrepreneurship in China Open

Mengtao Chen, Yongming Sun, Weiqi Zhang · 2025

Loss-of-function mutations of microRNA-142-3p promote <i>ASH1L</i> expression to induce immune evasion and hepatocellular carcinoma progression Open

Xiaotian Yu, Yan Xie, Jian Yu, Kunning Zhang, Zhiwen Guo , et al. · 2024

BACKGROUND Hepatocellular carcinoma (HCC) has been a pervasive malignancy throughout the world with elevated mortality. Efficient therapeutic targets are beneficial to treat and predict the disease. Currently, the exact molecular mechanism…

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