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View article: Corrigendum to “Quality evaluation of clinical practice guidelines for placenta accreta spectrum disorders” [Heliyon Volume 10, Issue 7, April 15 2025, Article e28390]
Corrigendum to “Quality evaluation of clinical practice guidelines for placenta accreta spectrum disorders” [Heliyon Volume 10, Issue 7, April 15 2025, Article e28390] Open
View article: De novo design of a fusion protein tool for GPCR research
De novo design of a fusion protein tool for GPCR research Open
G protein–coupled receptors (GPCRs) play pivotal roles in cellular signaling and represent prominent drug targets. Structural elucidation of GPCRs is crucial for drug discovery efforts. However, structural studies of GPCRs remain challengi…
View article: Antibody tocolysis targeting oxytocin receptor
Antibody tocolysis targeting oxytocin receptor Open
Preterm birth, defined as delivery before 37 weeks of gestation, poses significant risks to maternal and neonatal health. These risks include neonatal respiratory distress syndrome, intraventricular hemorrhage, long-term developmental chal…
View article: Classification of hemostatic methods and their efficacy in placenta increta
Classification of hemostatic methods and their efficacy in placenta increta Open
Vascular hemostasis and combined hemostasis may be better than uterine hemostasis alone for placenta increta without temporary hemostasis. Prospective and large-scale studies are needed to investigate long-term outcomes and confirm the eff…
View article: Trends in research on preterm birth in twin pregnancy based on bibliometrics
Trends in research on preterm birth in twin pregnancy based on bibliometrics Open
Background Twin pregnancies are associated with a higher risk of perinatal mortality compared to singleton pregnancies. This study evaluated the developmental trends and summarized the key features of research on preterm births in twin pre…
View article: Risk Factors and Predictors of Adverse Outcomes in Twin Pregnancies: A Review
Risk Factors and Predictors of Adverse Outcomes in Twin Pregnancies: A Review Open
Objective: Twin pregnancies are associated with a higher risk of adverse pregnancy outcomes than are singleton pregnancies. Although the risk factors and predictors of adverse outcomes in singleton pregnancies have been clearly identified …
View article: Predicting cervical insufficiency in twin pregnancies using ultrasound cervical measurements and elastography
Predicting cervical insufficiency in twin pregnancies using ultrasound cervical measurements and elastography Open
Background: To evaluate the predictive effect of transvaginal ultrasound measurement of cervical length and cervical elasticity examination on cervical insufficiency in twin pregnancies. Methods: Data from twin pregnant women…
View article: Pregnancy outcomes of twin pregnancies with cervical insufficiency undergoing cervical cerclage
Pregnancy outcomes of twin pregnancies with cervical insufficiency undergoing cervical cerclage Open
View article: Early prediction of placenta accreta spectrum by evaluation of risk factors and ultrasound
Early prediction of placenta accreta spectrum by evaluation of risk factors and ultrasound Open
Introduction We explored the predictive utility of clinical risk factors and first-trimester pregnancy ultrasound signs for severe placenta accreta spectrum. Material and methods Patients with placenta accreta spectrum treated in our insti…
View article: Quality evaluation of clinical practice guidelines for placenta accreta spectrum disorders
Quality evaluation of clinical practice guidelines for placenta accreta spectrum disorders Open
The current guidelines for PAS demonstrate commendable methodological and reporting qualities. However, the methodological and reporting quality of PAS CPGs still need to be further improved, particularly in stakeholder involvement, the ri…
View article: Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway
Huc-MSC-derived exosomal miR-144 alleviates inflammation in LPS-induced preeclampsia-like pregnant rats via the FosB/Flt-1 pathway Open
We found that huc-Exos-MSC-derived miR-144 alleviated gestational hypertension and inflammation in PE-like pregnant rats by regulating the FosB/Flt-1 pathway. In addition, huc-Exos-MSC-derived miR-144 could partially reverse the LPS-induce…
View article: Structures of human prostaglandin F2α receptor reveal the mechanism of ligand and G protein selectivity
Structures of human prostaglandin F2α receptor reveal the mechanism of ligand and G protein selectivity Open
Prostaglandins and their receptors regulate various physiological processes. Carboprost, an analog of prostaglandin F 2α and an agonist for the prostaglandin F2-alpha receptor (FP receptor), is clinically used to treat postpartum hemorrhag…
View article: CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation.
CircHIPK3/miR-124 affects angiogenesis in early-onset preeclampsia via CPT1A-mediated fatty acid oxidation. Open
Multiple theories have been proposed to explain the pathogenesis of early-onset preeclampsia (EOPE), and angiogenic dysfunction is an important part of the pathogenesis. Carnitine palmitoyltransferase (CPT1A) is a key rate-limiting enzyme …
View article: Termination of a second-trimester pregnancy with placenta accreta spectrum disorder
Termination of a second-trimester pregnancy with placenta accreta spectrum disorder Open
Background: The termination of pregnancy in patients with placenta accreta spectrum disorder (PASD) during the second trimester remains uncertain. In addition, interventional radiology techniques, such as arterial embolization and b…
View article: Una variedad de factores influyen en los tratamientos de COVID-19
Una variedad de factores influyen en los tratamientos de COVID-19 Open
View article: A variety of factors influence COVID-19 treatments
A variety of factors influence COVID-19 treatments Open
View article: Multiomics‐based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis
Multiomics‐based study of amniotic fluid small extracellular vesicles identified Moesin as a biomarker for antenatal hydronephrosis Open
Dear Editor, Antenatal hydronephrosis (ANH) is the most common congenital anomaly of the urinary tract. Pregnancy outcome and fetal prognosis are closely related to the severity of ANH.1 Approximately 15%−20% of children with ANH result in…
View article: Evaluation of Guidelines and Consensus on Ectopic Pregnancy Based by AGREE II Method
Evaluation of Guidelines and Consensus on Ectopic Pregnancy Based by AGREE II Method Open
The overall quality of the ectopic pregnancy guidelines had room for improvement. It is recommended to supplement and improve the four fields of "independence", "rigor", "participants" and "application", especially the "independence" and "…
View article: Development of the Scientific, Transparent and Applicable Rankings (STAR) tool for clinical practice guidelines
Development of the Scientific, Transparent and Applicable Rankings (STAR) tool for clinical practice guidelines Open
Background: This study aimed to develop a comprehensive instrument for evaluating and ranking clinical practice guidelines, named Scientific, Transparent and Applicable Rankings tool (STAR), and test its reliability, validity, and usabilit…
View article: FP receptor structures reveal the selectivity mechanism of prostaglandin
FP receptor structures reveal the selectivity mechanism of prostaglandin Open
Prostaglandins and their receptors regulate various physiological processes, such as cardiovascular homeostasis, body temperature control and female production. Carboprost, an analog of prostaglandin F2α and an agonist for the prostaglandi…
View article: 3D Printing and Its Current Status of Application in Obstetrics and Gynecological Diseases
3D Printing and Its Current Status of Application in Obstetrics and Gynecological Diseases Open
3D printing technology is a novel method of utilizing computer-generated three-dimensional models for drawing, assembling special bioinks, and manufacturing artificial organs and biomedical products. In recent years, it has evolved into a …
View article: Comparison of risk assessments for venous thromboembolism during the puerperium
Comparison of risk assessments for venous thromboembolism during the puerperium Open
The predictive value of different risk assessment methods for puerperium VTE varies greatly. Considering the sensitivity and specificity, the Swedish method may have better clinical application value among the 11 methods.
View article: Maternal and fetal benefits of fetal reduction in triplet pregnancies
Maternal and fetal benefits of fetal reduction in triplet pregnancies Open
Introduction Triplet pregnancy is a type of high-risk pregnancy that often results in premature delivery. Although fetal reduction is recommended, a number of factors can lead to triplet pregnancies without reduction. As there is no consen…
View article: Multiomics-Based Study of Amniotic Fluid Small Extracellular Vesicles Identified Moesin as a Biomarker for Antenatal Hydronephrosis
Multiomics-Based Study of Amniotic Fluid Small Extracellular Vesicles Identified Moesin as a Biomarker for Antenatal Hydronephrosis Open
View article: A predictive nomogram for a failed trial of labor after cesarean: A retrospective cohort study
A predictive nomogram for a failed trial of labor after cesarean: A retrospective cohort study Open
Aim To validate risk factors and a nomogram prediction model for the failure of a trial of labor after cesarean section (TOLAC) in a Chinese population. Methods We included women who tried TOLAC between January 2017 and May 2019, grouped a…
View article: Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats
Supplementation with dietary omega-3 PUFA mitigates fetal brain inflammation and mitochondrial damage caused by high doses of sodium nitrite in maternal rats Open
Objective Food safety and nutrition during pregnancy are important concerns related to fetal brain development. In the present study, we aimed to explore the effects of omega-3 polyunsaturated fatty acids (PUFA ω-3) on exogenous sodium nit…
View article: Intrauterine infusion of clinically graded human umbilical cord-derived mesenchymal stem cells for the treatment of poor healing after uterine injury: a phase I clinical trial
Intrauterine infusion of clinically graded human umbilical cord-derived mesenchymal stem cells for the treatment of poor healing after uterine injury: a phase I clinical trial Open
View article: A Biomedical Approach for Investigating the Pressure Fluctuation Inside High-Speed Passenger Train
A Biomedical Approach for Investigating the Pressure Fluctuation Inside High-Speed Passenger Train Open
View article: How to think about severe acute respiratory syndrome coronavirus 2 vaccination for pregnant and lactating women in China.
How to think about severe acute respiratory syndrome coronavirus 2 vaccination for pregnant and lactating women in China. Open
The coronavirus disease 2019 (COVID-19) continues to spread around the world, and how to build an immune barrier against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the population is the work we need to do for a lon…
View article: Deciphering the Intercellular Communication Network of Peripartum Decidua that Orchestrates Delivery
Deciphering the Intercellular Communication Network of Peripartum Decidua that Orchestrates Delivery Open
Intercellular communication in the decidua plays important roles in relaying information between the maternal and fetal systems in the maintenance of pregnancy and the transition to labor. To date, several studies have explored cell-cell c…