Weixiang Lu
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View article: Comparison of short-term outcomes between non-intubated and intubated video-assisted thoracoscopic surgery: a propensity score matching analysis
Comparison of short-term outcomes between non-intubated and intubated video-assisted thoracoscopic surgery: a propensity score matching analysis Open
View article: The global, regional, and national burden of Non-Hodgkin lymphoma in 204 countries and territories and 811 subnational locations, 1990–2021: an update from the Global Burden of Disease Study 2021
The global, regional, and national burden of Non-Hodgkin lymphoma in 204 countries and territories and 811 subnational locations, 1990–2021: an update from the Global Burden of Disease Study 2021 Open
Non-Hodgkin lymphoma (NHL) constitutes a significant portion of the global cancer burden and associated mortality. However, a comprehensive understanding of NHL's scale and trends remains limited, underscoring the need for evidence-based e…
View article: Shared genetics of lung cancer and type 2 diabetes: a large-scale genome-wide cross-trait analysis
Shared genetics of lung cancer and type 2 diabetes: a large-scale genome-wide cross-trait analysis Open
This study provides robust evidence of a shared genetic architecture between LCA subtypes and T2D, highlighting potential therapeutic targets. Future research should focus on validating these findings in larger cohorts and exploring the fu…
View article: Epidemiology and survival of patients with primary lymphoma of bone: a large retrospective cohort study
Epidemiology and survival of patients with primary lymphoma of bone: a large retrospective cohort study Open
Primary lymphoma of bone (PLB) is a rare extranodal lymphoma, and its epidemiology and prognosis remain controversial. We conducted a retrospective analysis of 1,222 patients with PLB in the Surveillance, Epidemiology, and End Results (SEE…
View article: Characteristics of second primary malignancies following bispecific antibodies therapy
Characteristics of second primary malignancies following bispecific antibodies therapy Open
Background The risk of secondary primary malignancies (SPMs) associated with bispecific antibody (BsAb)—a promising alternative to chimeric antigen receptor (CAR)-T therapy—remains insufficiently explored. Methods Using large-scale, real-w…
View article: Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy
Refining prognostic assessment of diffuse large B-cell lymphoma: insights from multi-omics and single-cell analysis unveil SRM as a key target for regulating immunotherapy Open
Purposes Previous studies have demonstrated that proliferation, stroma or immunity strongly influence the prognosis and therapeutic resistance of diffuse large B-cell lymphoma (DLBCL). Herein, we aimed to integrate proliferation, stromal, …
View article: Comparison of CAR T-cell and bispecific antibody as third-line or later-line treatments for multiple myeloma: a meta-analysis
Comparison of CAR T-cell and bispecific antibody as third-line or later-line treatments for multiple myeloma: a meta-analysis Open
Background CAR-T-cell therapy and bispecific antibody have revolutionized the treatment landscape for multiple myeloma. However, there is currently a lack of studies comparing the efficacy and safety of these two approaches. This meta-anal…
View article: Latent class analysis‐derived classification improves the cancer‐specific death stratification of lymphomas: <scp>A</scp> large retrospective cohort study
Latent class analysis‐derived classification improves the cancer‐specific death stratification of lymphomas: <span>A</span> large retrospective cohort study Open
Lymphomas have diverse etiologies, treatment approaches, and prognoses. Accurate survival estimation is challenging for lymphoma patients due to their heightened susceptibility to non‐lymphoma‐related mortality. To overcome this challenge,…
View article: LungPath: artificial intelligence-driven histologic pattern recognition for improved diagnosis of early-stage invasive lung adenocarcinoma
LungPath: artificial intelligence-driven histologic pattern recognition for improved diagnosis of early-stage invasive lung adenocarcinoma Open
We have developed a deep learning algorithm, LungPath, for the automated segmentation of pulmonary nodules and prediction of high-risk histological patterns in early-stage lung ADC based on CT scans.
View article: Fine-grained image classification method based on hybrid attention module
Fine-grained image classification method based on hybrid attention module Open
To efficiently capture feature information in tasks of fine-grained image classification, this study introduces a new network model for fine-grained image classification, which utilizes a hybrid attention approach. The model is built upon …
View article: Upfront surgery for stage IIIA/B non-small cell lung cancer: retrospective cohort study
Upfront surgery for stage IIIA/B non-small cell lung cancer: retrospective cohort study Open
Background Stage III non-small cell lung cancer is a heterogeneous disease. Several international guidelines recommend neoadjuvant treatment before surgery; however, upfront surgery is the preferred approach for technically resectable non-…
View article: Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single‐Cell Transcriptomics
Behind the Indolent Facade: Uncovering the Molecular Features and Malignancy Potential in Lung Minimally Invasive Adenocarcinoma by Single‐Cell Transcriptomics Open
The increased use of low‐dose computed tomography screening has led to more frequent detection of early stage lung tumors, including minimally invasive adenocarcinoma (MIA). To unravel the intricacies of tumor cells and the immune microenv…
View article: Target genes of N6-methyladenosine regulatory protein ALKBH5 are associated with prognosis of patients with lung adenocarcinoma
Target genes of N6-methyladenosine regulatory protein ALKBH5 are associated with prognosis of patients with lung adenocarcinoma Open
This study provides potential therapeutic targets for LUAD and a basis for further studies on the mechanism underlying the effects of ALKBH5.
View article: A risk score for predicting postoperative complications in non-intubated thoracic surgery
A risk score for predicting postoperative complications in non-intubated thoracic surgery Open
This simple risk score model based on risk factors of postoperative complications can validly identify the high-risk patients with postoperative complications in the non-intubated VATS, and allow for early interventions.
View article: Early extubation in operating room after single-lung transplantation: a single institutional experience
Early extubation in operating room after single-lung transplantation: a single institutional experience Open
Early endotracheal extubation in operating room was feasible and did not delay postoperative recovery in these 18 lung transplantation recipients.
View article: Risk Factors for the Development of Intraoperative Hypoxia in Patients Undergoing Nonintubated Video-Assisted Thoracic Surgery: A Retrospective Study from a Single Center
Risk Factors for the Development of Intraoperative Hypoxia in Patients Undergoing Nonintubated Video-Assisted Thoracic Surgery: A Retrospective Study from a Single Center Open
BACKGROUND Nonintubated video-assisted thoracic surgery (NIVATS) has been demonstrated to be safe and effective in patients. However, the risk factors for intraoperative hypoxia are unclear. This retrospective study aimed to identify the r…
View article: A risk score for predicting postoperative complications in non-intubated thoracic surgery
A risk score for predicting postoperative complications in non-intubated thoracic surgery Open
Background The risk factors for postoperative complications in non-intubated video-assisted thoracoscopic surgery (VATS) has not been observed before. Here to develop a simple risk score to predict the risk of postoperative complications f…
View article: Non-Intubated Anesthesia Video-Assisted Thoracic Surgery for Subxiphoid Anterior Mediastinal Tumor Resection
Non-Intubated Anesthesia Video-Assisted Thoracic Surgery for Subxiphoid Anterior Mediastinal Tumor Resection Open
Objective Subxiphoid approach for mediastinal tumor resection was reported to provide a better view and less postoperative pain. Non-intubated video-assisted thoracic surgery (NI-VATS) without muscle relaxant would decrease the possibility…
View article: Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China
Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China Open