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Second-Harmonic Generation of the Vortex Beams with Integer and Fractional Topological Charges Open

Shirui Zhang, Weizhou Hou, Xin Tao, Minghao Guo, Yueqing Li , et al. · 2023

The single-pass second-harmonic generation (SHG) of a vortex beam under low fundamental wave depletion is systematically studied. Vortex modes at 1064 nm with integer topological charges from ±1 to ±9 and fractional ones at ±0.75 are gener…

Data from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Multiple studies have associated the transcription factor IRF1 with tumor-suppressive activities. Here, we report an opposite tumor cell–intrinsic function of IRF1 in promoting tumor growth. IRF1-deficient tumor cells showed reduced tumor …

Data from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Multiple studies have associated the transcription factor IRF1 with tumor-suppressive activities. Here, we report an opposite tumor cell–intrinsic function of IRF1 in promoting tumor growth. IRF1-deficient tumor cells showed reduced tumor …

Supplementary Figure legends from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure legends

Figure S4 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S4

Figure S4 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S4

Figure S3 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S3

Figure S2 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S2

Figure S2 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S2

Figure S3 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S3

Supplementary Figure legends from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure legends

Figure S1 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S1

Figure S1 from IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2023

Supplementary Figure S1

Supplemental Figures S1-5 from Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy Open

Juan J. Rojas, Padma Sampath, Weizhou Hou, Steve H. Thorne · 2023

Supplemental Figures S1-5. S1: isotype controls and ctla-4 effects on viral replication; S2: effects of anti-CD25; S3: B18R effects on Treg and NK cells; S4: gating for T-cells and NK cells; S5: effects of IFNg depletion

Data from Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy Open

Juan J. Rojas, Padma Sampath, Weizhou Hou, Steve H. Thorne · 2023

Purpose: Recent data from randomized clinical trials with oncolytic viral therapies and with cancer immunotherapies have finally recapitulated the promise these platforms demonstrated in preclinical models. Perhaps the greatest adva…

Data from Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy Open

Juan J. Rojas, Padma Sampath, Weizhou Hou, Steve H. Thorne · 2023

Purpose: Recent data from randomized clinical trials with oncolytic viral therapies and with cancer immunotherapies have finally recapitulated the promise these platforms demonstrated in preclinical models. Perhaps the greatest adva…

Supplemental Figures S1-5 from Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy Open

Juan J. Rojas, Padma Sampath, Weizhou Hou, Steve H. Thorne · 2023

Supplemental Figures S1-5. S1: isotype controls and ctla-4 effects on viral replication; S2: effects of anti-CD25; S3: B18R effects on Treg and NK cells; S4: gating for T-cells and NK cells; S5: effects of IFNg depletion

IRF1 Inhibits Antitumor Immunity through the Upregulation of PD-L1 in the Tumor Cell Open

Lulu Shao, Weizhou Hou, Nicole E. Scharping, Frank P. Vendetti, Rashmi Srivastava , et al. · 2019

Multiple studies have associated the transcription factor IRF1 with tumor-suppressive activities. Here, we report an opposite tumor cell–intrinsic function of IRF1 in promoting tumor growth. IRF1-deficient tumor cells showed reduced tumor …

Oncolytic Virus-Mediated Targeting of PGE 2 in the Tumor Alters the Immune Status and Sensitizes Established and Resistant Tumors to Immunotherapy Open

Weizhou Hou, Padma Sampath, Juan J. Rojas, Steve H. Thorne · 2016

Manipulating TLR Signaling Increases the Anti-tumor T Cell Response Induced by Viral Cancer Therapies Open

Juan J. Rojas, Padma Sampath, Braulio Bonilla, Alexandra Ashley, Weizhou Hou , et al. · 2016

The immune response plays a key role in enhancing the therapeutic activity of oncolytic virotherapies. However, to date, investigators have relied on inherent interactions between the virus and the immune system, often coupled to the expre…

HIF-1α, ATP5β and CAIX expression have greater heterogeneity in HypoxiSense-positive tumors as compared to HypoxiSense-negative tumors. Open

C. Nakajima Erica, Laymon Charles, Oborski Matthew, Weizhou Hou, Lin Wang , et al. · 2015

Mean, standard deviation (SD), and coefficient of variance (CV) of staining were quantified by measuring positive pixel count in 20 representative regions of each tumor slice using Aperio version 9. Quantification of protein expression in …

Fluoromodule-based reporter/probes designed for in vivo fluorescence imaging Open

Ming Zhang, Subhasish Chakraborty, Padma Sampath, Juan J. Rojas, Weizhou Hou , et al. · 2015

Optical imaging of whole, living animals has proven to be a powerful tool in multiple areas of preclinical research and has allowed noninvasive monitoring of immune responses, tumor and pathogen growth, and treatment responses in longitudi…

Defining Effective Combinations of Immune Checkpoint Blockade and Oncolytic Virotherapy Open

Juan J. Rojas, Padma Sampath, Weizhou Hou, Steve H. Thorne · 2015

Purpose: Recent data from randomized clinical trials with oncolytic viral therapies and with cancer immunotherapies have finally recapitulated the promise these platforms demonstrated in preclinical models. Perhaps the greatest advance wit…

The analysis and research of simulation test in Voltage Controlled Oscillator circuit Open

Weizhou Hou · 2015

The Voltage Controlled Oscillator circuit had been analyzed in virtual test via NI Multisim 10.1 software.By changing the input DC voltage, the changing rule of the output waveform was observed, has read the cycle and calculate the frequen…

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