Xian Wang
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View article: Tongxinluo capsule for acute myocardial infarction: a systematic review and meta-analysis
Tongxinluo capsule for acute myocardial infarction: a systematic review and meta-analysis Open
Objective To evaluate the clinical and preclinical effects of Tongxinluo Capsule (TXL) on acute myocardial infarction (AMI) and to summarize reported mechanisms of action, thereby informing clinical decision-making and future research. Met…
View article: Case Report: Intraosseous schwannoma of the thoracic spine: two case reports and an updated review of the literature
Case Report: Intraosseous schwannoma of the thoracic spine: two case reports and an updated review of the literature Open
Intraosseous schwannomas (IOSs) are benign tumors composed of nerve sheath cells, representing less than 0.2% of primary bone tumors. These tumors most commonly affect the mandible and sacrum, while vertebral involvement remains exceedingl…
View article: Tongxinluo Capsule for Acute Myocardial Infarction: A Systematic Review and Meta-analysis
Tongxinluo Capsule for Acute Myocardial Infarction: A Systematic Review and Meta-analysis Open
View article: Efficacy of manual therapy for cervical vertigo: a randomized controlled trial protocol
Efficacy of manual therapy for cervical vertigo: a randomized controlled trial protocol Open
International Traditional Medicine Clinical Trials, ITMCTR2025000184. Registered on 25 January 2025.
View article: ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery
ED50 and ED95 of hypobaric ropivacaine during unilateral spinal anesthesia in older patients undergoing hip replacement surgery Open
Objective The spinal block was limited to the operative side during unilateral spinal anesthesia, which has less physiological interference and fewer complications for the patient. The optimal dose of ropivacaine for unilateral spinal anes…
View article: Androgens alleviate the depression-like phenotype in female mice by inhibiting AVPR1a in the hippocampal brain region
Androgens alleviate the depression-like phenotype in female mice by inhibiting AVPR1a in the hippocampal brain region Open
View article: A comparative analysis of three graph neural network models for predicting axillary lymph node metastasis in early-stage breast cancer
A comparative analysis of three graph neural network models for predicting axillary lymph node metastasis in early-stage breast cancer Open
View article: Identification of the Valine-Glutamine gene family in Chenopodium quinoa Willd and analysis of its expression pattern and subcellular localization under drought stress
Identification of the Valine-Glutamine gene family in Chenopodium quinoa Willd and analysis of its expression pattern and subcellular localization under drought stress Open
View article: Development and Validation of an Interpretable Prediction Model for Early Screening of Acute Myocardial Infarction in Young and Middle-Aged Patients
Development and Validation of an Interpretable Prediction Model for Early Screening of Acute Myocardial Infarction in Young and Middle-Aged Patients Open
Background: In recent years, the incidence of acute myocardial infarction (AMI) has been rising among young individuals. However, existing research predominantly concentrates on AMI patients who are elderly. This study employs machine lear…
View article: Effect of acupuncture on quality of life in atrial fibrillation: study protocol for a randomised controlled trial
Effect of acupuncture on quality of life in atrial fibrillation: study protocol for a randomised controlled trial Open
Introduction Atrial fibrillation (AF) is the prevalent cardiac arrhythmia and can significantly impair the quality of life (QoL). Although catheter ablation (CA) is an established treatment for AF,post-procedural complications or perceived…
View article: Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor–Positive Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer: Primary Results From TROPION-Breast01
Datopotamab Deruxtecan Versus Chemotherapy in Previously Treated Inoperable/Metastatic Hormone Receptor–Positive Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer: Primary Results From TROPION-Breast01 Open
PURPOSE The global, phase 3, open-label, randomized TROPION-Breast01 study assessed the trophoblast cell surface antigen 2–directed antibody-drug conjugate datopotamab deruxtecan (Dato-DXd) versus investigator's choice of chemotherapy (ICC…
View article: Clinical best practices in interdisciplinary management of human epidermal growth factor receptor 2 antibody‐drug conjugates–induced interstitial lung disease/pneumonitis: An expert consensus in China
Clinical best practices in interdisciplinary management of human epidermal growth factor receptor 2 antibody‐drug conjugates–induced interstitial lung disease/pneumonitis: An expert consensus in China Open
Antibody–drug conjugates (ADCs) have demonstrated effectiveness in treating various cancers, particularly exhibiting specificity in targeting human epidermal growth factor receptor 2 (HER2)‐positive breast cancer. Recent advancements in ph…
View article: Trastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer: long-term survival analysis of the DESTINY-Breast03 trial
Trastuzumab deruxtecan versus trastuzumab emtansine in HER2-positive metastatic breast cancer: long-term survival analysis of the DESTINY-Breast03 trial Open
Trastuzumab deruxtecan (T-DXd) demonstrated significantly improved efficacy over trastuzumab emtansine (T-DM1) in DESTINY-Breast03 (median follow-up, 28 months). We report updated efficacy and safety analyses, including secondary and explo…
View article: Systemic immune inflammation index and system inflammation response index on the third postoperative day predict poor prognosis of aneurysmal subarachnoid hemorrhage patients
Systemic immune inflammation index and system inflammation response index on the third postoperative day predict poor prognosis of aneurysmal subarachnoid hemorrhage patients Open
The inflammatory response is involved in the progression of aneurysmal subarachnoid hemorrhage (aSAH). We sought to investigate the relationships of inflammatory indicators including blood cell counts and the ratios of different blood cell…
View article: Effectiveness and safety of early lens extraction during par plana vitrectomy for proliferative diabetes retinopathy with mild cataract: a randomized clinical trial
Effectiveness and safety of early lens extraction during par plana vitrectomy for proliferative diabetes retinopathy with mild cataract: a randomized clinical trial Open
AIM: To evaluate the effectiveness and safety of early lens extraction during pars plana vitrectomy (PPV) for proliferative diabetic retinopathy (PDR) compared to those of PPV with subsequent cataract surgery. METHODS: This multicenter ran…
View article: Construction of a Nomogram-Based Prediction Model for the Risk of Diabetic Kidney Disease in T2DM
Construction of a Nomogram-Based Prediction Model for the Risk of Diabetic Kidney Disease in T2DM Open
The risk of DKD in T2DM could be predicted accurately by DR, hypertension, history of gout, smoking history, using insulin, elevation of BMI, TG, Cys-C, and reduction of 25 (OH) D.
View article: N-Doped Carbon-Encapsulated Bimetallic Diselenide Nanoparticles@Rgo As High-Rate Dual-Salt Battery Cathode Via Lattice-Confinement Strategy
N-Doped Carbon-Encapsulated Bimetallic Diselenide Nanoparticles@Rgo As High-Rate Dual-Salt Battery Cathode Via Lattice-Confinement Strategy Open
View article: Genetically predicted hypertension, antihypertensive drugs, and risk of erectile dysfunction: a Mendelian randomization study
Genetically predicted hypertension, antihypertensive drugs, and risk of erectile dysfunction: a Mendelian randomization study Open
Background The causal relationship between hypertension, antihypertensive drugs and the risk of erectile dysfunction is still uncertain. We performed a univariable and multivariable Mendelian randomization study to investigate whether they…
View article: Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago
Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago Open
Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, but enable documentation of the history of antibody responses in an individual. The severe acute respiratory syndrome coronavirus 2 (SARS‐Co…
View article: Increase Renal Tubular Pressure to Treat Congestive Renal Failure
Increase Renal Tubular Pressure to Treat Congestive Renal Failure Open
Background: Congestive renal failure commonly result from cardiorenal syndrome related renal venous hypertension(RVH)，which is more linked to the renal venous pressure than mean arterial pressure and systematic vascular resistance. But its…
View article: Clinical Value of Three Combined Ultrasonography Modalities in Predicting the Risk of Metastasis to Axillary Lymph Nodes in Breast Invasive Ductal Carcinoma
Clinical Value of Three Combined Ultrasonography Modalities in Predicting the Risk of Metastasis to Axillary Lymph Nodes in Breast Invasive Ductal Carcinoma Open
Objective The present study aimed to assess the clinical value of conventional ultrasound (C-US), ultrasound elastography (UE), percutaneous contrast-enhanced ultrasound (P-CUES), and the combination of these three ultrasonography modaliti…
View article: Outcome of One-Stage Percutaneous Endoscopic Debridement and Lavage Combined with Percutaneous Pedicle Screw Fixation for Lumbar Pyogenic Spondylodiscitis
Outcome of One-Stage Percutaneous Endoscopic Debridement and Lavage Combined with Percutaneous Pedicle Screw Fixation for Lumbar Pyogenic Spondylodiscitis Open
Background This study assessed the therapeutic effect of one-stage percutaneous endoscopic debridement and lavage (PEDL) combined with percutaneous pedicle screw fixation (PPSF) in the treatment of lumbar pyogenic spondylodiscitis. Methods…
View article: Genome-wide identification, characterization and expression analysis of the LIM transcription factor family in quinoa
Genome-wide identification, characterization and expression analysis of the LIM transcription factor family in quinoa Open
View article: Acupuncture for persistent atrial fibrillation after catheter ablation: study protocol for a pilot randomized controlled trial
Acupuncture for persistent atrial fibrillation after catheter ablation: study protocol for a pilot randomized controlled trial Open
View article: Recent advances of SIRT1 and implications in chemotherapeutics resistance in cancer.
Recent advances of SIRT1 and implications in chemotherapeutics resistance in cancer. Open
Cancer is a big group of diseases and one of the leading causes of mortality worldwide. Despite enormous studies and efforts are being carried out in understanding the cancer and developing drugs against tumorigenesis, drug resistance is t…
View article: Effects of the pestle needle therapy, a type of acupoint stimulation, on post-hemorrhoidectomy pain: A randomized controlled trial
Effects of the pestle needle therapy, a type of acupoint stimulation, on post-hemorrhoidectomy pain: A randomized controlled trial Open
The pestle needle therapy was effective for relieving pain, reducing anxiety and improving bowel function after hemorrhoidectomy, and it is worthy of clinical application.
View article: Acute kidney injury following on-pump or off-pump coronary artery bypass grafting in elderly patients: a retrospective propensity score matching analysis
Acute kidney injury following on-pump or off-pump coronary artery bypass grafting in elderly patients: a retrospective propensity score matching analysis Open
View article: Efficacy and Safety of Recanalization Therapy for Acute Ischemic Stroke With Large Vessel Occlusion
Efficacy and Safety of Recanalization Therapy for Acute Ischemic Stroke With Large Vessel Occlusion Open
Background and Purpose: The optimal recanalization strategy for acute ischemic stroke with large vessel occlusion continues to be an area of active interest. Network meta-analysis can provide insight when direct comparative evidence is lac…
View article: Prospective randomized controlled trial study of Luofengning granule in the treatment of unstable angina
Prospective randomized controlled trial study of Luofengning granule in the treatment of unstable angina Open
Introduction: Although the current western treatment plans for unstable angina (UA) has been optimized in past decades, UA still is a common phenotype of acute coronary syndrome and significantly influence the quality of life and endanger …
View article: <p>Low Incidence of Maternal Near-Miss in Zhejiang, a Developed Chinese Province: A Cross-Sectional Study Using the WHO Approach</p>
Low Incidence of Maternal Near-Miss in Zhejiang, a Developed Chinese Province: A Cross-Sectional Study Using the WHO Approach Open
Overall near-miss indicators suggested a relatively high quality of maternal health care in a developed province of China. The identified risk factors may be helpful in developing targeted interventions for improving maternal safety.