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View article: Single-neuron projectome-guided analysis reveals the neural circuit mechanism underlying endogenous opioid antinociception
Single-neuron projectome-guided analysis reveals the neural circuit mechanism underlying endogenous opioid antinociception Open
Endogenous opioid antinociception is a self-regulatory mechanism that reduces chronic pain, but its underlying circuit mechanism remains largely unknown. Here, we showed that endogenous opioid antinociception required the activation of mu-…
View article: Spatially resolved molecular and cellular atlas of the mouse brain
Spatially resolved molecular and cellular atlas of the mouse brain Open
A comprehensive atlas of genes, cell types, and their spatial distribution across a whole mammalian brain is fundamental for understanding function of the brain. Here, using snRNA-seq and Stereo-seq techniques, we generated a mouse brain a…
View article: An atlas of itch-associated neural dynamics in the mouse brain
An atlas of itch-associated neural dynamics in the mouse brain Open
The itch-scratching cycle is mediated by neural dynamics in the brain. However, our understanding of the neural dynamics during this cycle remains limited. In this study, we examine the neural dynamics of 126 mouse brain areas by measuring…