William Ho
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View article: Hearing Health in Home Healthcare: Leveraging LLMs for Illness Scoring and ALMs for Vocal Biomarker Extraction
Hearing Health in Home Healthcare: Leveraging LLMs for Illness Scoring and ALMs for Vocal Biomarker Extraction Open
The growing demand for home healthcare calls for tools that can support care delivery. In this study, we explore automatic health assessment from voice using real-world home care visit data, leveraging the diverse patient information it co…
View article: Determinants of Adoption and Continuance Intention of Food Delivery Applications in Malaysia
Determinants of Adoption and Continuance Intention of Food Delivery Applications in Malaysia Open
In Malaysia’s competitive food delivery market, understanding factors that drive users’ continued platform use is essential. This study investigates the determinants influencing users’ continuance usage intention toward ShopeeFood in Malay…
View article: Tariff barriers and operational efficiency: the mitigative role of top management team supply chain management experience and potential domestic supply base
Tariff barriers and operational efficiency: the mitigative role of top management team supply chain management experience and potential domestic supply base Open
View article: Interactive Pattern Repetition Game Design Utilizing Real-Time Hardware Pseudo-Random Number Generator
Interactive Pattern Repetition Game Design Utilizing Real-Time Hardware Pseudo-Random Number Generator Open
View article: Investigating disruption propagation and resilience of supply chain networks: interplay of tiers and connections
Investigating disruption propagation and resilience of supply chain networks: interplay of tiers and connections Open
View article: Decoding the Interplay Between Supplier Network Flexibility and Financial Performance within the Buyer Network in Uncertain Business Environments
Decoding the Interplay Between Supplier Network Flexibility and Financial Performance within the Buyer Network in Uncertain Business Environments Open
Multinational corporations increasingly choose flexible suppliers over low-cost options to manage uncertainties effectively. While previous research highlights the importance of buyer network design for supplier flexibility and reconfigura…
View article: Solving the paradox of Lean Management’s low success rate
Solving the paradox of Lean Management’s low success rate Open
This study investigates problems related to the high variance in the success rate of lean implementations, using a unique data set from a specific approach to implementing lean. We develop insights about how to effectively resolve the ‘Lea…
View article: Factors Influencing the Resurgence of Supplier Sustainability Incidents
Factors Influencing the Resurgence of Supplier Sustainability Incidents Open
View article: Supplementary Figure 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Supplementary Figure 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
PDF file - 61K, Supplemental Figure 1. Human, cynomolgus monkey, and rat PBMCs were isolated from whole blood in accordance with BD Vacutainer CPT protocol. Mouse PBMCs were isolated from whole blood by ACK lysis buffer treatment to lyse…
View article: Data from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Data from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
Antibody–drug conjugates (ADC), potent cytotoxic drugs linked to antibodies via chemical linkers, allow specific targeting of drugs to neoplastic cells. We have used this technology to develop the ADC DCDT2980S that targets CD22, an antige…
View article: Data from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Data from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
Antibody–drug conjugates (ADC), potent cytotoxic drugs linked to antibodies via chemical linkers, allow specific targeting of drugs to neoplastic cells. We have used this technology to develop the ADC DCDT2980S that targets CD22, an antige…
View article: Supplementary Figure 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Supplementary Figure 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
PDF file - 61K, Supplemental Figure 1. Human, cynomolgus monkey, and rat PBMCs were isolated from whole blood in accordance with BD Vacutainer CPT protocol. Mouse PBMCs were isolated from whole blood by ACK lysis buffer treatment to lyse…
View article: Supplementary Table 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Supplementary Table 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
XLSX file - 30K, IC50 concentrations and CD22 expression levels for cell lines.
View article: Supplementary Table 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma
Supplementary Table 1 from DCDT2980S, an Anti-CD22-Monomethyl Auristatin E Antibody–Drug Conjugate, Is a Potential Treatment for Non-Hodgkin Lymphoma Open
XLSX file - 30K, IC50 concentrations and CD22 expression levels for cell lines.
View article: TMIC-61. LOSARTAN PREVENTS IMMUNOTHERAPY-ASSOCIATED EDEMA AND ENHANCES SURVIVAL IN GLIOBLASTOMA
TMIC-61. LOSARTAN PREVENTS IMMUNOTHERAPY-ASSOCIATED EDEMA AND ENHANCES SURVIVAL IN GLIOBLASTOMA Open
Immune checkpoint blockers (ICBs) have revolutionized the treatment of some solid cancers but have failed to benefit the majority of glioblastoma (GBM) patients. Two reasons underlying limited ICB benefit are: 1) immune-related adverse eve…
View article: 1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer
1241 IL-1 blockade prevents cardiac toxicity and improves immunotherapy efficacy in mouse models of pancreatic cancer Open
Background Immune checkpoint blockers (ICBs) have revolutionized cancer treatment, but they are often associated with severe immune related adverse events (irAEs). These severe irAEs are more often seen in patients with obesity or concomit…
View article: 658 A phase 2 study to assess the safety, efficacy of FLX475 combined with pembrolizumab in patients with advanced or metastatic gastric cancer
658 A phase 2 study to assess the safety, efficacy of FLX475 combined with pembrolizumab in patients with advanced or metastatic gastric cancer Open
Background Regulatory T-cells (Treg) maintain homeostasis and self-tolerance, but can also suppress anti-tumor immunity in the tumor microenvironment (TME), correlating with poor clinical outcomes. C-C chemokine receptor type 4 …
View article: RETRACTED ARTICLE: Evaluating sustainably resilient supply chains: a stochastic double frontier analytic model considering Netzero
RETRACTED ARTICLE: Evaluating sustainably resilient supply chains: a stochastic double frontier analytic model considering Netzero Open
View article: The impact of chief risk officer appointments on firm risk and operational efficiency
The impact of chief risk officer appointments on firm risk and operational efficiency Open
To exercise risk control at the corporate level, firms often appoint Chief Risk Officers (CROs) to their top management team. By establishing CRO positions, firms can reduce firm risk and potential financial losses caused by operational di…
View article: Impact of Internal Environmental Uncertainty and Knowledge Leveraging on Manufacturing Plant’s Financial Performance
Impact of Internal Environmental Uncertainty and Knowledge Leveraging on Manufacturing Plant’s Financial Performance Open
Businesses are unclear about which levels of knowledge leveraging from suppliers and customers increase the financial performance in internal uncertain business environments. Therefore, this study first aims to explore how the leveraging o…
View article: Impact of Environmental Uncertainty and Contractual Embeddedness on Supplier's Sales Probability
Impact of Environmental Uncertainty and Contractual Embeddedness on Supplier's Sales Probability Open
Existing literature offers limited knowledge about online markets that consist of open contractual and supply networks. Online markets allow consumers to develop their supply chains by choosing suppliers from the open contractual network. …
View article: Supplier’s contractual embeddedness and sales performance in uncertain environments
Supplier’s contractual embeddedness and sales performance in uncertain environments Open
Literature offers limited knowledge on the online markets that consist of both open contractual and supply networks which are subject to environmental uncertainties. This study investigates how the environmental uncertainty dimensions and …
View article: Supplier Embeddedness and Relational Performance in Toyota Buyer Network in Uncertain Business Environments
Supplier Embeddedness and Relational Performance in Toyota Buyer Network in Uncertain Business Environments Open
Existing literature offers limited knowledge about the supplier embeddedness and relational performance in global buyer network under business environmental uncertainties. Therefore, this study first develops the empirical context, a part …
View article: Supplier and customer knowledge leveraging and financial performance nexus: moderating effects of the internal manufacturing environment
Supplier and customer knowledge leveraging and financial performance nexus: moderating effects of the internal manufacturing environment Open
Exponentially growing knowledge and technology create dynamic but different expectations for customer and supplier leveraging practices in both knowledge exploitation and exploration. Although manufacturers equally adopt the imitable knowl…
View article: Coordinated Pricing Analysis with the Carbon Tax Scheme in a Supply Chain*
Coordinated Pricing Analysis with the Carbon Tax Scheme in a Supply Chain* Open
The carbon tax is a cost‐efficient scheme to curb emissions, and it has been implemented in Australia, British Columbia, and other places worldwide. We aim to analyze its effect on dynamic pricing in a supply chain with multiple suppliers …
View article: Models for supplier selection and risk mitigation: a holistic approach
Models for supplier selection and risk mitigation: a holistic approach Open
According to a study conducted by PwC and the Business Continuity Institute in 2013, 75% of companies experience at least one major supply chain disruption a year and majority of the disruptions were caused by supply-related problems. With…
View article: Design and application of Internet of things-based warehouse management system for smart logistics
Design and application of Internet of things-based warehouse management system for smart logistics Open
Warehouse operations need to change due to the increasing complexity and variety of customer orders. The demand for real-time data and contextual information is requried because of the highly customised orders, which tend to be of small ba…
View article: The state-of-the-art integrations and applications of the analytic hierarchy process
The state-of-the-art integrations and applications of the analytic hierarchy process Open
View article: A multiple colonies artificial bee colony algorithm for a capacitated vehicle routing problem and re-routing strategies under time-dependent traffic congestion
A multiple colonies artificial bee colony algorithm for a capacitated vehicle routing problem and re-routing strategies under time-dependent traffic congestion Open
View article: Effect of health information exchange on recognition of medication discrepancies is interrupted when data charges are introduced: results of a cluster-randomized controlled trial
Effect of health information exchange on recognition of medication discrepancies is interrupted when data charges are introduced: results of a cluster-randomized controlled trial Open
Objectives To determine the effect of health information exchange (HIE) on medication prescribing for hospital inpatients in a cluster-randomized controlled trial, and to examine the prescribing effect of availability of information from a…