Wenyuan Ding
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View article: Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells
Heme oxygenase 1‑overexpressing bone marrow mesenchymal stem cell‑derived exosomes suppress interleukin‑1 beta‑induced apoptosis and aging of nucleus pulposus cells Open
Exosomes derived from bone marrow mesenchymal stem cells (BMSCs) and heme oxygenase 1 (HO‑1) attenuate intervertebral disc degeneration (IVDD). However, whether BMSC‑derived exosomes attenuate IVDD by delivering HO‑1 to nucleus pulposus (N…
View article: Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions
Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions Open
Background Chronic low back pain (LBP) is a significant global health concern, often linked to vertebral bone marrow lesions (BML), particularly fatty replacement (FR). This study aims to explore the relationship between the gut microbiome…
View article: Therapeutic Effects of Pcf on Acute Myocardial Infarction with Depression Through Attenuation of S100a9/Nlrp3-Mediated Inflammatory Response and Enhancement of Mitochondrial Energy Metabolism by Integrating Transcriptomics, Animal Experiments and Cellular Experiments
Therapeutic Effects of Pcf on Acute Myocardial Infarction with Depression Through Attenuation of S100a9/Nlrp3-Mediated Inflammatory Response and Enhancement of Mitochondrial Energy Metabolism by Integrating Transcriptomics, Animal Experiments and Cellular Experiments Open
View article: <scp>ERAP1</scp> Gene Variants and Haplotypes Associated With Psoriasis Vulgaris of Han Chinese in Inner Mongolia
<span>ERAP1</span> Gene Variants and Haplotypes Associated With Psoriasis Vulgaris of Han Chinese in Inner Mongolia Open
Background This study aimed to investigate the association between genetic variants of ERAP1 (OMIM: 606832) and psoriasis vulgaris (PsV) susceptibility in Inner Mongolia Han nationality. Methods For primary screening, the subjects included…
View article: Impact of Lumbar Fusion Internal Fixation on Lumbar Disc Herniation in Young Patients: A Retrospective Study
Impact of Lumbar Fusion Internal Fixation on Lumbar Disc Herniation in Young Patients: A Retrospective Study Open
BACKGROUND Lumbar fusion and internal fixation techniques have shown promise in treating lumbar disc herniation (LDH), yet the impact on lumbar function in young patients remains unclear. This study aimed to investigate the impact of lumba…
View article: Inherited genetic predisposition and imaging concordance in degenerative lumbar scoliosis patients and their descendants
Inherited genetic predisposition and imaging concordance in degenerative lumbar scoliosis patients and their descendants Open
Genetic influences are significant in the onset of DLS, with affected families showing similar scoliosis patterns and identical apex vertebrae. Moreover, individuals with genetic mutations tend to have more pronounced vertebral rotation an…
View article: Enlarged posterior column osteotomy plus intervertebral cage strutting for lumbosacral nerve bowstring disease
Enlarged posterior column osteotomy plus intervertebral cage strutting for lumbosacral nerve bowstring disease Open
View article: Characteristic of Paraspinal Muscle Change in Coronal Sub‐type of Degenerative Lumbar Scoliosis and its Potential Clinical Significance
Characteristic of Paraspinal Muscle Change in Coronal Sub‐type of Degenerative Lumbar Scoliosis and its Potential Clinical Significance Open
Objective Clarifying paraspinal muscle (PM) change in degenerative lumbar scoliosis (DLS) is positive to evaluate the progression of scoliosis. This research compares the characteristic of PM change among different coronal sub‐types of DLS…
View article: Early rhythm control in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III
Early rhythm control in patients with recently diagnosed atrial fibrillation: findings from the GLORIA-AF Registry Phase III Open
Background Early rhythm control (ERC) can improve outcomes in select patients with atrial fibrillation (AF) but real-world data are lacking. Purpose To evaluate the effectiveness of ERC in a real-world cohort of AF patients. Methods From t…
View article: Comparison of radiological and clinical outcomes of cervical laminoplasty versus lateral mass screw fixation in patients with ossification of the posterior longitudinal ligament
Comparison of radiological and clinical outcomes of cervical laminoplasty versus lateral mass screw fixation in patients with ossification of the posterior longitudinal ligament Open
Purpose This study aimed to compare cervical sagittal parameters and clinical outcomes between patients undergoing cervical laminoplasty(CL) and those undergoing lateral mass screw fixation(LMS). Methods We retrospectively studied 67 patie…
View article: Sex-based differences in clinical and radiological presentation of patients with degenerative lumbar scoliosis: a cross-sectional study
Sex-based differences in clinical and radiological presentation of patients with degenerative lumbar scoliosis: a cross-sectional study Open
View article: Comparison of Cervical Sagittal Parameters among Patients with Neck Pain and Patients with Cervical Spondylotic Radiculopathy and Cervical Spondylotic Myelopathy
Comparison of Cervical Sagittal Parameters among Patients with Neck Pain and Patients with Cervical Spondylotic Radiculopathy and Cervical Spondylotic Myelopathy Open
Objective Previous studies have shown that cervical sagittal alignment is strongly associated with cervical deformity, myelopathy, and cervical adjacent‐segmental disease, and these cervical sagittal parameters are correlated with health‐r…
View article: Enlarged posterior column osteotomy plus intervertebral cage strutting as a exploratory surgery for lumbosacral Nerve bowstring disease: a retrospective retrospective study
Enlarged posterior column osteotomy plus intervertebral cage strutting as a exploratory surgery for lumbosacral Nerve bowstring disease: a retrospective retrospective study Open
Background : To explore the surgical outcome of enlarged posterior column osteotomy plus intervertebral cage strutting for patients with lumbosacral nerve bowstring disease. Methods :The clinical data of 27 patients with bowstring disease …
View article: Incidence and Predictive Factors of New Onset Postoperative Sacroiliac Joint Pain After Posterior Lumbar Fusion Surgery for Degenerative Lumbar Disease
Incidence and Predictive Factors of New Onset Postoperative Sacroiliac Joint Pain After Posterior Lumbar Fusion Surgery for Degenerative Lumbar Disease Open
PSJP for degenerative lumbar disease was 5.4%, the predictive factors included preoperative severe infiltration of LMM, distal fusion level at sacrum and higher HU value.
View article: Impact of oral anticoagulants in frail atrial fibrillation patients: a report from an observational registry of european patients
Impact of oral anticoagulants in frail atrial fibrillation patients: a report from an observational registry of european patients Open
Background The last years showed a substantial increase of interest about the clinical issue of frailty among patients with cardiovascular diseases. Impact of frailty in atrial fibrillation (AF) has been examined in terms of management, qu…
View article: Prevalence and Risk Factors for Modic Changes in Symptomatic Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Study of 203 Patients
Prevalence and Risk Factors for Modic Changes in Symptomatic Cervical Ossification of the Posterior Longitudinal Ligament: A Retrospective Study of 203 Patients Open
BACKGROUND Modic changes (MC) are abnormal bone signals under the vertebral endplates on magnetic resonance imaging (MRI) of the spine. Three types of MC may be seen on MRI as abnormal bone signals of the vertebral endplate and adjacent bo…
View article: Epidemiological and clinical features, treatment status, and economic burden of traumatic spinal cord injury in China: a hospital-based retrospective study
Epidemiological and clinical features, treatment status, and economic burden of traumatic spinal cord injury in China: a hospital-based retrospective study Open
JOURNAL/nrgr/04.03/01300535-202405000-00044/inline-graphic1/v/2023-09-28T063346Z/r/image-tiff Traumatic spinal cord injury is potentially catastrophic and can lead to permanent disability or even death. China has the largest population of …
View article: Low back pain and osteoarthritis pain: a perspective of estrogen
Low back pain and osteoarthritis pain: a perspective of estrogen Open
Low back pain (LBP) is the world’s leading cause of disability and is increasing in prevalence more rapidly than any other pain condition. Intervertebral disc (IVD) degeneration and facet joint osteoarthritis (FJOA) are two common causes o…
View article: Disease-associated gut microbiome and metabolome changes in chronic low back pain patients with bone marrow lesions
Disease-associated gut microbiome and metabolome changes in chronic low back pain patients with bone marrow lesions Open
Chronic low back pain (LBP) is the leading cause of global disability. Vertebral bone marrow lesions (BMLs), one etiological factor for chronic LBP, are MRI signal changes in the vertebral bone marrow that extend from the disc endplate. Th…
View article: Comparison of radiological and clinical outcomes of cervical laminoplasty versus lateral mass screw fixation in patients with ossification of the posterior longitudinal ligament
Comparison of radiological and clinical outcomes of cervical laminoplasty versus lateral mass screw fixation in patients with ossification of the posterior longitudinal ligament Open
Purpose This study aimed to compare cervical sagittal parameters and clinical outcomes between patients undergoing cervical laminoplasty(CL) and those undergoing lateral mass screw fixation(LMS). Methods We retrospectively studied 67 patie…
View article: Erratum. <i>TRB3</i> Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model. Diabetes 2011;60:2963–2974
Erratum. <i>TRB3</i> Gene Silencing Alleviates Diabetic Cardiomyopathy in a Type 2 Diabetic Rat Model. Diabetes 2011;60:2963–2974 Open
In the article cited above, there was inadvertent echocardiographic image overlap between Fig. 2A and Fig. 6B due to errors during image processing. The correct Fig. 6B is shown below. The authors apologize for the error. The online versio…
View article: Characteristics of the paravertebral muscle in adult degenerative scoliosis with PI-LL match or mismatch and risk factors for PI-LL mismatch
Characteristics of the paravertebral muscle in adult degenerative scoliosis with PI-LL match or mismatch and risk factors for PI-LL mismatch Open
Objective Pelvic incidence (PI) minus the lumbar lordosis (LL) angle (PI-LL) correlates with function and disability. It is associated with paravertebral muscle (PVM) degeneration and is a valuable tool for surgical planning of adult degen…
View article: Comparison of cervical sagittal parameters among patients with neck pain and patients with cervical spondylotic radiculopathy and cervical spondylotic myelopathy
Comparison of cervical sagittal parameters among patients with neck pain and patients with cervical spondylotic radiculopathy and cervical spondylotic myelopathy Open
Purpose: Previous studies have shown that cervical sagittal alignment is strongly associated with cervical deformity, myelopathy,and cervical adjacent-segmental disease, and those cervical sagittal parameters are correlated with health-rel…
View article: Reliability of end, stable, neutral, first coronal reverse vertebrae identification in degenerative lumbar scoliosis: Intra- and interobserver consistency analysis
Reliability of end, stable, neutral, first coronal reverse vertebrae identification in degenerative lumbar scoliosis: Intra- and interobserver consistency analysis Open
Objective To assess the intra- and interobserver reliability by observer training level used for selecting the end vertebra (EV), neutral vertebra (NV), stable vertebra (SV), and first coronal reverse vertebrae (FCRV) in degenerative lumba…
View article: Variation characteristics of cervical sagittal parameters between patients with nonspecific neck pain and patients with radiculotic and cervical spondylotic myelopathy: A cross-sectional study
Variation characteristics of cervical sagittal parameters between patients with nonspecific neck pain and patients with radiculotic and cervical spondylotic myelopathy: A cross-sectional study Open
Purpose: To compare the variation characteristics of cervical sagittal position parameters and the correlation among nonspecific neck pain(NS-NP), cervical spondylotic radiculopathy (CSR), and cervical spondylotic myelopathy (CSM). Methods…
View article: Comparison of C2 dome-like laminectomy with C2 partial laminectomy for upper cervical ossification of the posterior longitudinal ligament
Comparison of C2 dome-like laminectomy with C2 partial laminectomy for upper cervical ossification of the posterior longitudinal ligament Open
Objective To compare surgical outcomes of C2 dome-like laminectomy with C2 partial laminectomy in patients with ossification of the posterior longitudinal ligament (OPLL) up to the C2 level and above. Methods 32 patients underwent surgical…
View article: The treatment effect of posterior lumbar fusion surgery on patients suffering from lumbar disc herniation concurrent with peroneal nerve paralysis
The treatment effect of posterior lumbar fusion surgery on patients suffering from lumbar disc herniation concurrent with peroneal nerve paralysis Open
Purpose The purpose of this study is to investigate the clinical effect of posterior lumbar fusion surgery on patients who suffer from lumbar disc herniation concurrent with peroneal nerve paralysis. Methods The patients suffering from per…
View article: The Diagnostic Value of Blood Next-Generation Sequencing in Early Surgical Site Infection After Spine Surgery
The Diagnostic Value of Blood Next-Generation Sequencing in Early Surgical Site Infection After Spine Surgery Open
This article emphasizes the superiority of blood NGS in infection detection and bacterial determination in patients undergoing spine surgery. Compared with traditional drainage fluid bacterial culture and NGS, blood NGS was more sensitive …
View article: Predictors and tactics for revision surgery in lateral lumbar interbody fusion
Predictors and tactics for revision surgery in lateral lumbar interbody fusion Open
View article: Analysis of the surgical strategy and postoperative clinical effect of thoracic ossification of ligament flavum with dural ossification
Analysis of the surgical strategy and postoperative clinical effect of thoracic ossification of ligament flavum with dural ossification Open
Purpose Our research was designed to analyse the postoperative clinical results of patients suffering from single-segment thoracic ossification of the ligamentum flavum (TOLF) combined with dural ossification (DO) who underwent posterior l…