Yu Ouyang
YOU?
Author Swipe
View article: Cell-Membrane-Anchored Synthetic Dynamic DNA Circuits for Signaling Transient Cell Migration
Cell-Membrane-Anchored Synthetic Dynamic DNA Circuits for Signaling Transient Cell Migration Open
A DNA reaction circuit consisting of components E/Q1, E1/T1, F/Q1, and F1/T1 in which each includes the antimesenchymal epithelial transition (Met) receptor aptamer sequence…
View article: Adenosine-Triggered Dynamic and Transient Aptamer-Based Networks Integrated in Liposome Protocell Assemblies
Adenosine-Triggered Dynamic and Transient Aptamer-Based Networks Integrated in Liposome Protocell Assemblies Open
The development of transient dissipative nucleic-acid-based reaction circuits and constitutional dynamic networks attracts growing interest as a means of emulating native dynamic reaction circuits. Recent efforts applying enzymes, DNAzymes…
View article: A Programmed DNA Dynamic Assembly‐Guided Molecular Amplifier for Authentic Information Decryption
A Programmed DNA Dynamic Assembly‐Guided Molecular Amplifier for Authentic Information Decryption Open
Nucleic acid‐based cryptographic approaches are an innovative emerging field for information process. However, the poor reproducibility and interference from bioenvironment of the existing decryption led to different binary translation acc…
View article: Spatiotemporal dynamic and catalytically mediated reconfiguration of compartmentalized cyanuric acid/polyadenine DNA microdroplet condensates
Spatiotemporal dynamic and catalytically mediated reconfiguration of compartmentalized cyanuric acid/polyadenine DNA microdroplet condensates Open
View article: Photomodulated Transient Catalytic Constitutional Dynamic Networks and Reaction Circuits
Photomodulated Transient Catalytic Constitutional Dynamic Networks and Reaction Circuits Open
A method to photomodulate dynamically transient DNA‐based reaction circuits and networks is introduced. The method relies on the integration of photoresponsive o‐nitrobenzyl‐phosphate ester‐caged DNA hairpin with a “mute” reaction module. …
View article: Photomodulated Transient Catalytic Constitutional Dynamic Networks and Reaction Circuits
Photomodulated Transient Catalytic Constitutional Dynamic Networks and Reaction Circuits Open
A method to photomodulate dynamically transient DNA‐based reaction circuits and networks is introduced. The method relies on the integration of photoresponsive o‐nitrobenzyl‐phosphate ester‐caged DNA hairpin with a “mute” reaction module. …
View article: Prediction of Trihalomethane Occurrence and Cancer Risk Using Interpretable Machine Learning and Virtual Data Augmentation
Prediction of Trihalomethane Occurrence and Cancer Risk Using Interpretable Machine Learning and Virtual Data Augmentation Open
View article: Clusterin-carrying extracellular vesicles derived from human umbilical cord mesenchymal stem cells restore the ovarian function of premature ovarian failure mice through activating the PI3K/AKT pathway
Clusterin-carrying extracellular vesicles derived from human umbilical cord mesenchymal stem cells restore the ovarian function of premature ovarian failure mice through activating the PI3K/AKT pathway Open
Administration of UC-MSCs and UC-MSCs-derived EVs on day 6 of CTX/BUS injection could effectively improve the ovarian function of POF mice. UC-MSCs-derived EVs carrying CLU promoted proliferation and inhibited apoptosis of ovarian granulos…
View article: DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications
DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications Open
Self‐assembled supramolecular DNA tetrahedra composed of programmed sequence‐engineered complementary base‐paired strands represent elusive nanostructures having key contributions to the development and diverse applications of DNA nanotech…
View article: The impact of coaxial gas technology on the morphology of powder by gas atomisation and the additive manufactured mechanical performance
The impact of coaxial gas technology on the morphology of powder by gas atomisation and the additive manufactured mechanical performance Open
Metal powders are essential for additive manufacturing (AM), with their morphology significantly impacting the performance of AM components. Gas atomisation (GA) is a common method for producing metal powders due to its efficiency and cost…
View article: DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications
DNA Tetrahedra as Functional Nanostructures: From Basic Principles to Applications Open
Self‐assembled supramolecular DNA tetrahedra composed of programmed sequence‐engineered complementary base‐paired strands represent elusive nanostructures having key contributions to the development and diverse applications of DNA nanotech…
View article: Spatially Localized Entropy-Driven Evolution of Nucleic Acid-Based Constitutional Dynamic Networks for Intracellular Imaging and Spatiotemporal Programmable Gene Therapy
Spatially Localized Entropy-Driven Evolution of Nucleic Acid-Based Constitutional Dynamic Networks for Intracellular Imaging and Spatiotemporal Programmable Gene Therapy Open
The primer-guided entropy-driven high-throughput evolution of the DNA-based constitutional dynamic network, CDN, is introduced. The entropy gain associated with the process provides a catalytic principle for the amplified emergence of the …
View article: Phototriggered Equilibrated and Transient Orthogonally Operating Constitutional Dynamic Networks Guiding Biocatalytic Cascades
Phototriggered Equilibrated and Transient Orthogonally Operating Constitutional Dynamic Networks Guiding Biocatalytic Cascades Open
The photochemical deprotection of structurally engineered o-nitrobenzylphosphate-caged hairpin nucleic acids is introduced as a versatile method to evolve constitutional dynamic networks, CDNs. The photogenerated CDNs, in the presen…
View article: Stiffness‐Switchable, Biocatalytic pH‐Responsive DNA‐Functionalized Polyacrylamide Cryogels and their Mechanical Applications
Stiffness‐Switchable, Biocatalytic pH‐Responsive DNA‐Functionalized Polyacrylamide Cryogels and their Mechanical Applications Open
The large‐pore interconnected channels in cryogels, allow convectional flow and rapid mass‐transport of solute constituents between the solution and cryogel polymer framework, as compared to slower, diffusionally‐controlled mass‐transport …
View article: Dynamic DNA Networks-Guided Directional and Orthogonal Transient Biocatalytic Cascades
Dynamic DNA Networks-Guided Directional and Orthogonal Transient Biocatalytic Cascades Open
DNA frameworks, consisting of constitutional dynamic networks (CDNs) undergoing fuel-driven reconfiguration, are coupled to a dissipative reaction module that triggers the reconfigured CDNs into a transient intermediate CDNs recovering the…
View article: Stimuli‐Responsive Hydrogel Microcapsules Harnessing the COVID‐19 Immune Response for Cancer Therapeutics
Stimuli‐Responsive Hydrogel Microcapsules Harnessing the COVID‐19 Immune Response for Cancer Therapeutics Open
The combination of gene therapy and immunotherapy concepts, along recent advances in DNA nanotechnology, have the potential to provide important tools for cancer therapies. We present the development of stimuli‐responsive microcapsules, lo…
View article: Stimuli‐Responsive Hydrogel Microcapsules Harnessing the COVID‐19 Immune Response for Cancer Therapeutics
Stimuli‐Responsive Hydrogel Microcapsules Harnessing the COVID‐19 Immune Response for Cancer Therapeutics Open
The combination of gene therapy and immunotherapy concepts, along recent advances in DNA nanotechnology, have the potential to provide important tools for cancer therapies. We present the development of stimuli‐responsive microcapsules, lo…
View article: Transient Dynamic Operation of G-Quadruplex-Gated Glucose Oxidase-Loaded ZIF-90 Metal–Organic Framework Nanoparticle Bioreactors
Transient Dynamic Operation of G-Quadruplex-Gated Glucose Oxidase-Loaded ZIF-90 Metal–Organic Framework Nanoparticle Bioreactors Open
Glucose oxidase-loaded ZIF-90 metal-organic framework nanoparticles conjugated to hemin-G-quadruplexes act as functional bioreactor hybrids operating transient dissipative biocatalytic cascaded transformations consisting of the glucose-dri…
View article: Cascaded, Feedback-Driven, and Spatially Localized Emergence of Constitutional Dynamic Networks Driven by Enzyme-Free Catalytic DNA Circuits
Cascaded, Feedback-Driven, and Spatially Localized Emergence of Constitutional Dynamic Networks Driven by Enzyme-Free Catalytic DNA Circuits Open
The enzyme-free catalytic hairpin assembly (CHA) process is introduced as a functional reaction module for guided, high-throughput, emergence, and evolution of constitutional dynamic networks, CDNs, from a set of nucleic acids. The process…
View article: Three Compartment Liposome Fusion: Functional Protocells for Biocatalytic Cascades and Operation of Dynamic DNA Machineries
Three Compartment Liposome Fusion: Functional Protocells for Biocatalytic Cascades and Operation of Dynamic DNA Machineries Open
Nucleic acid‐functionalized liposomes modified at their boundaries with o‐nitrobenzyl phosphate‐caged hairpin units and pH‐responsive C‐G·C + triplex forming strands are used for the concomitant light and pH‐triggered fusion of three types…
View article: Aptamer‐Modified Homogeneous Catalysts, Heterogenous Nanoparticle Catalysts, and Photocatalysts: Functional “Nucleoapzymes”, “Aptananozymes”, and “Photoaptazymes”
Aptamer‐Modified Homogeneous Catalysts, Heterogenous Nanoparticle Catalysts, and Photocatalysts: Functional “Nucleoapzymes”, “Aptananozymes”, and “Photoaptazymes” Open
Conjugation of aptamers to homogeneous catalysts (“nucleoapzymes”), heterogeneous nanoparticle catalysts (“aptananozymes”), and photocatalysts (“photoaptazymes”) yields superior catalytic/photocatalytic hybrid nanostructures emulating func…
View article: ODDFUZZ: Discovering Java Deserialization Vulnerabilities via Structure-Aware Directed Greybox Fuzzing
ODDFUZZ: Discovering Java Deserialization Vulnerabilities via Structure-Aware Directed Greybox Fuzzing Open
Java deserialization vulnerability is a severe threat in practice. Researchers have proposed static analysis solutions to locate candidate vulnerabilities and fuzzing solutions to generate proof-of-concept (PoC) serialized objects to trigg…
View article: Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy
Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy Open
Diabetic nephropathy (DN) is one of the microvascular complications of diabetes. Recent studies suggest that the pyroptosis of renal tubular epithelial cell plays a critical role in DN. Currently, effective therapeutic strategies to counte…
View article: Improving Java Deserialization Gadget Chain Mining via Overriding-Guided Object Generation
Improving Java Deserialization Gadget Chain Mining via Overriding-Guided Object Generation Open
Java (de)serialization is prone to causing security-critical vulnerabilities that attackers can invoke existing methods (gadgets) on the application's classpath to construct a gadget chain to perform malicious behaviors. Several techniques…
View article: Optical and Electrochemical Probes for Monitoring Cytochrome c in Subcellular Compartments During Apoptosis
Optical and Electrochemical Probes for Monitoring Cytochrome c in Subcellular Compartments During Apoptosis Open
Cytochrome c (Cyt. c ) is a key initiator of the caspases that activate cell apoptosis. The spatiotemporal evaluation of the contents of Cyt. c in cellular compartments and the detection of Cyt. c delivery between cellular compartments upo…
View article: Optical and Electrochemical Probes for Monitoring Cytochrome c in Subcellular Compartments During Apoptosis
Optical and Electrochemical Probes for Monitoring Cytochrome c in Subcellular Compartments During Apoptosis Open
Cytochrome c (Cyt. c ) is a key initiator of the caspases that activate cell apoptosis. The spatiotemporal evaluation of the contents of Cyt. c in cellular compartments and the detection of Cyt. c delivery between cellular compartments upo…
View article: Understanding the breakup behaviors of liquid jet in gas atomization for powder production
Understanding the breakup behaviors of liquid jet in gas atomization for powder production Open
Gas atomization (GA) is the main method to produce metal powders for additive manufacturing (AM) because of its low cost and high efficiency. However, the liquid breakup behaviors in high-speed gas flow during GA remains unclear, especiall…
View article: Efficiency Recycling and Utilization of Phosphate from Wastewater Using LDHs-Modified Biochar
Efficiency Recycling and Utilization of Phosphate from Wastewater Using LDHs-Modified Biochar Open
The excessive application of phosphate fertilizers easily causes water eutrophication. Phosphorus recovery by adsorption is regarded as an effective and simple intervention to control water bodies’ eutrophication. In this work, a series of…
View article: MSFR-GCN: A Multi-Scale Feature Reconstruction Graph Convolutional Network for EEG Emotion and Cognition Recognition
MSFR-GCN: A Multi-Scale Feature Reconstruction Graph Convolutional Network for EEG Emotion and Cognition Recognition Open
Graph Convolutional Network (GCN) excels at EEG recognition by capturing brain connections, but previous studies neglect the important EEG feature itself. In this study, we propose MSFR-GCN, a multi-scale feature reconstruction GCN for rec…
View article: Current Situation, Challenges and Prospects of Geothermal Energy Development in China
Current Situation, Challenges and Prospects of Geothermal Energy Development in China Open
Based on the geothermal resource conditions, the current situation of China's geothermal energy utilization in heating (cooling), power generation, hot spring bathing, high-end seed breeding, and hot dry rock exploration and development ar…